LEADER 02665nam  2200673 a 450 
001 9910812788203321
005 20240516115341.0
010   $a9786613454225
010   $a9783527644780
010   $a3527644784
010   $a9781283454223
010   $a128345422X
010   $a9783527644827
010   $a3527644822
010   $a9783527644797
010   $a3527644792
035   $a(CKB)2550000000084138
035   $a(EBL)851166
035   $a(OCoLC)775871780
035   $a(SSID)ssj0000642007
035   $a(PQKBManifestationID)11458699
035   $a(PQKBTitleCode)TC0000642007
035   $a(PQKBWorkID)10628609
035   $a(PQKB)11613742
035   $a(MiAaPQ)EBC851166
035   $a(Au-PeEL)EBL851166
035   $a(CaPaEBR)ebr10531468
035   $a(CaONFJC)MIL345422
035   $a(Perlego)1011201
035   $a(EXLCZ)992550000000084138
100   $a20120309d2012      uy         0
101 0 $aeng
135   $aur|n|---|||||
181   $ctxt
182   $cc
183   $acr
200 00$aTherapeutic proteins $estrategies to modulate their plasma half-lives /$fedited by Roland Kontermann
205   $a1st ed.
210   $aWeinheim, Germany $cWiley-Blackwell$d2012
215   $a1 online resource (374 p.)
300   $aDescription based upon print version of record.
311 08$a9783527328499 
311 08$a3527328491 
320   $aIncludes bibliographical references and index.
327   $apt. 1. General information -- pt. 2. Half-life extension through chemical and post-translational modifications -- pt. 3. Half-life modulation involving recycling by the neonatal Fc receptor -- pt. 4. Half-life extension with pharmaceutical formulations.
330   $aFor this ready reference, the internationally renowned authority in the field, Roland Kontermann, has assembled a team of outstanding contributors from industry and academia to convey the worldwide knowledge on modifying therapeutic proteins in order to optimize their pharmacological potential. The result is a comprehensive work covering all approaches and aspects of the topic in one handy volume, making this indispensable reading for companies and research institutions working on the development of biopharmaceuticals.
606   $aProtein drugs$xDesign
606   $aProteins$xTherapeutic use
615  0$aProtein drugs$xDesign.
615  0$aProteins$xTherapeutic use.
676   $a615.3
701   $aKontermann$b Roland$01621064
801  0$bMiAaPQ
801  1$bMiAaPQ
801  2$bMiAaPQ
906   $aBOOK
912   $a9910812788203321
996   $aTherapeutic proteins$93954182
997   $aUNINA