LEADER 05321nam 2200613 450 001 9910812710303321 005 20170822104210.0 010 $a0-12-397778-9 035 $a(CKB)3710000000276870 035 $a(EBL)1834153 035 $a(SSID)ssj0001415345 035 $a(PQKBManifestationID)11846208 035 $a(PQKBTitleCode)TC0001415345 035 $a(PQKBWorkID)11342761 035 $a(PQKB)11702384 035 $a(MiAaPQ)EBC1834153 035 $a(PPN)252718623 035 $a(EXLCZ)993710000000276870 100 $a20141212h20152015 uy 0 101 0 $aeng 135 $aur|n|---||||| 181 $ctxt 182 $cc 183 $acr 200 00$aStem cell biology and tissue engineering in dental sciences /$fedited by Ajaykumar Vishwakarma [and three others] ; contributors, Samad Ahadian [and one hundred and ninety-seven others] 210 1$aLondon, [England] :$cAcademic Press,$d2015. 210 4$d©2015 215 $a1 online resource (933 p.) 300 $aDescription based upon print version of record. 311 $a0-12-397157-8 320 $aIncludes bibliographical references at the end of each chapters and index. 327 $aFront Cover; Stem Cell Biology and Tissue Engineering in Dental Sciences; Copyright; Contents; List of Contributors; Foreword; Chapter 1: An Introduction to Stem Cell Biology and Tissue Engineering; 1.1. Introduction; 1.2. The emergence of Tissue Engineering and regenerative medicine; 1.3. Research themes underlying Tissue Engineering technology; 1.3.1. Cells; 1.3.2. Biomaterial Scaffolds; 1.3.3. Tissue-Inducing Factors; 1.3.4. Devices and Systems; 1.4. Stem cell-based therapy; 1.4.1. Pure Stem Cell Therapy; 1.4.2. Scaffold-Based Stem Cell Therapy; 1.5. Translational Tissue Engineering 327 $a1.6. ConclusionReferences; Part I: Developmental Biology: A Blueprint for Tissue Engineering; Chapter 2: Developmentally Inspired Regenerative Organ Engineering: Tooth as a Model ; 2.1. Introduction; 2.2. Understanding generation for regeneration strategies: a tooth model; 2.3. Epithelial-mesenchymal interactions during odontogenesis; 2.4. ECM and mechanical forces as regulators of organogenesis; 2.5. Engineering approaches for tooth organ regeneration; 2.6. Conclusion; References; Chapter 3: Extracellular Matrix Molecules; 3.1. Introduction; 3.1.1. Overview 327 $a3.1.2. Extracellular Matrix Proteins3.1.3. Crosslinking; 3.2. Collagens; 3.2.1. Collagen Biosynthesis and Processing; 3.2.2. Fibril-Forming Collagens; 3.2.2.1. Biomineralization; 3.2.3. Fibril-Associated Collagens (FACITs); 3.2.4. Network-Forming Collagens; 3.2.5. Anchoring Fibrils; 3.2.6. Other Collagens; 3.2.7. Collagenopathies; 3.2.7.1. Osteogenesis Imperfecta (OI); 3.2.7.2. Ehlers-Danlos Syndrome; 3.2.7.3. Skeletal Dysplasias and Chondrodysplasias; 3.2.7.4. Other Collagenopathies; 3.3. Glycoproteins; 3.3.1. Fibronectin; 3.3.2. Fibrillins and Latent TGF-ß-Binding Proteins (LTBPs) 327 $a3.3.2.1. Structural and Functional Properties of Fibrillins and LTBPs3.3.2.2. Fibrillinopathies; 3.3.3. Fibulins; 3.3.4. Other Glycoproteins; 3.3.4.1. Tenascin; 3.3.4.2. The Small Integrin-Binding Ligand N-Linked Glycoproteins (SIBLINGs); 3.3.4.3. Thrombospondins; 3.4. Elastin and Elastic Fibers; 3.4.1. Elastic Fiber Assembly; 3.4.2. Elastin-Associated Pathologies; 3.5. Basement Membranes; 3.5.1. Laminins; 3.5.2. Collagen Type IV; 3.5.3. Basement Membrane Proteoglycans; 3.5.4. Basement Membrane-Associated Pathologies; 3.6. Proteoglycans and Glycosaminoglycans; 3.6.1. Glycosaminoglycans 327 $a3.6.2. Proteoglycans3.6.2.1. Cell Surface Proteoglycans; 3.6.2.2. Modular Proteoglycans; 3.6.2.3. Small Leucine Rich Proteoglycans (SLRPs); 3.7. Concluding Remarks; Acknowledgments; Abbreviations; References; Chapter 4: Cell-Matrix Interactions and Signal Transduction; 4.1. Introduction; 4.1.1. The First Evidence that Matrices Change Cell Behavior; 4.1.2. Integrin and Non-Integrin Receptor Discovery; 4.2. Receptors; 4.2.1. Integrins: Mediators of Cell-Matrix Interactions; 4.2.1.1. Integrin a Subunits; 4.2.1.2. Integrin ß Subunits; 4.2.2. Non-Integrin Receptors for ECM Molecules 327 $a4.2.2.1. Syndecans 330 $aStem Cell Biology and Tissue Engineering in Dental Sciences bridges the gap left by many tissue engineering and stem cell biology titles to highlight the importance of research in this field in the dental sciences. It compiles basic embryology and developmental biology with keen focus on stem cells, basic cell and matrix biology with relevance to tissue regeneration and repair, biomaterials (including nanotechnology) and current applications in various disciplines of dental science. Tissue engineering is an interdisciplinary field of biomedical research-which combines life, engineering, and ma 606 $aTissue engineering 606 $aStem cells 606 $aDentistry 615 0$aTissue engineering. 615 0$aStem cells. 615 0$aDentistry. 676 $a612.028 702 $aVishwakarma$b Ajaykumar 702 $aAhadian$b Samad 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910812710303321 996 $aStem cell biology and tissue engineering in dental sciences$94114150 997 $aUNINA