LEADER 05043nam 2200721 450 001 9910812289903321 005 20200520144314.0 010 $a1-118-65515-X 010 $a1-118-65518-4 010 $a1-118-65519-2 035 $a(CKB)3710000000468825 035 $a(EBL)2197326 035 $a(SSID)ssj0001544272 035 $a(PQKBManifestationID)16136733 035 $a(PQKBTitleCode)TC0001544272 035 $a(PQKBWorkID)14792602 035 $a(PQKB)10513797 035 $a(PQKBManifestationID)16140772 035 $a(PQKB)23303509 035 $a(MiAaPQ)EBC4037303 035 $a(DLC) 2015008593 035 $a(MiAaPQ)EBC2197326 035 $a(Au-PeEL)EBL4037303 035 $a(CaPaEBR)ebr11111633 035 $a(CaONFJC)MIL826461 035 $a(OCoLC)904400113 035 $a(Au-PeEL)EBL2197326 035 $a(PPN)204423449 035 $a(EXLCZ)993710000000468825 100 $a20151111h20152015 uy 0 101 0 $aeng 135 $aur|n|---||||| 181 $ctxt 182 $cc 183 $acr 200 10$aEsophageal cancer and Barrett's esophagus /$fPrateek Sharma, Richard Sampliner, David Ilson 205 $aThird edition. 210 1$aChichester, West Sussex, [England] :$cWiley Blackwell,$d2015. 210 4$dİ2015 215 $a1 online resource (313 p.) 300 $aPreceded by Barrett's esophagus and esophageal adenocarcinoma / edited by Prateek Sharma, Richard Sampliner. 2nd ed. 2006. 311 $a0-632-04509-4 311 $a1-118-65520-6 320 $aIncludes bibliographical references at the end of each chapters and index. 327 $aCover; Title Page; Copyright; Contents; List of contributors; Preface; Chapter 1 Epidemiology of esophageal carcinoma; 1.1 The incidence and mortality related to esophageal cancer; 1.2 Mortality; 1.3 Risk factors for EA; Chapter 2 Barrett's esophagus: definition and diagnosis; 2.1 Introduction; 2.2 Early history of Barrett's esophagus; 2.3 Early reports on the histology of Barrett's esophagus; 2.4 Identification of the gastroesophageal junction; 2.5 Recognition of short segment Barrett's esophagus; 2.6 Intestinal metaplasia and adenocarcinoma of the esophagus 327 $a2.7 The problem of cardiac mucosa2.8 Definition of Barrett's esophagus; 2.9 Diagnostic criteria for Barrett's esophagus; 2.10 Intestinal metaplasia at the GEJ; Chapter 3 Epidemiology and prevalence of Barrett's esophagus; 3.1 Introduction; 3.2 BE prevalence; 3.3 BE incidence; 3.4 Etiology and risk factors for BE; 3.5 Neoplastic progression risk in BE; 3.6 Conclusions; Chapter 4 Esophageal adenocarcinoma: risk factors; 4.1 Introduction; 4.2 Gastroesophageal reflux disease (GERD); 4.3 Barrett's esophagus (BE); 4.4 Obesity; 4.5 Smoking; 4.6 Alcohol; 4.7 Dietary factors; 4.8 Medication use 327 $a4.9 H. pylori4.10 Demographics; 4.11 Summary; Chapter 5 Esophageal motility abnormalities in Barrett's esophagus; 5.1 Introduction; 5.2 Antireflux barrier; 5.3 Lower esophageal sphincter; 5.4 Diaphragmatic sphincter and hiatal hernia; 5.5 Mechanical properties of the relaxed EGJ; 5.6 Esophageal clearance; 5.7 Peristaltic dysfunction; 5.8 Gastric emptying and duodenogastroesophageal reflux; 5.9 Therapy of motor abnormalities in Barrett's esophagus; 5.10 Conclusion; Chapter 6 Molecular biology of Barrett's esophagus and esophageal adenocarcinoma; 6.1 Introduction 327 $a6.2 Genetic and host susceptibility6.3 Environmental factors contributing to the development of BE; 6.4 Genomic instability mutations and copy number changes in candidate genes; 6.5 The advent of next generation sequencing; 6.6 Future directions and conclusions; Chapter 7 Histology of Barrett's esophagus: metaplasia and dysplasia; 7.1 Introduction; 7.2 Normal anatomy and histology; 7.3 Histology of Barrett's esophagus; 7.4 Intestinal metaplasia of the EGJ; 7.5 Barrett's esophagus-related dysplasia; 7.6 Intramucosal adenocarcinoma (IMC); 7.7 Submucosal adenocarcinoma 327 $a7.8 Morphologic types of dysplasia7.9 Sampling error and observer variation in Barrett's esophagus-related dysplasia; 7.10 Surrogate biomarkers for assessing risk of esophageal adenocarcinoma; Chapter 8 Helicobacter pylori and esophageal neoplasia; 8.1 Introduction; 8.2 H. pylori infection - gastritis pattern and gastric physiology with impact on gastroesophageal reflux disease; 8.3 Epidemiological studies - GERD symptoms, erosive esophagitis and H. pylori; 8.4 H. pylori, Barrett's esophagus and esophageal adenocarcinoma; 8.5 H. pylori eradication and GERD 327 $a8.6 H. pylori and esophageal squamous cell carcinoma 606 $aEsophagus$xCancer 615 0$aEsophagus$xCancer. 676 $a616.99/432 700 $aSharma$b Prateek$0849795 702 $aSampliner$b Richard E. 702 $aIlson$b David$g(David H.), 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910812289903321 996 $aEsophageal cancer and Barrett's esophagus$93953817 997 $aUNINA