LEADER 04961nam 22006014a 450 001 9910812215603321 005 20240416234808.0 010 $a1-280-18680-1 010 $a9786610186808 010 $a0-309-56996-6 010 $a0-585-18213-2 035 $a(CKB)110986584752254 035 $a(OCoLC)44964138 035 $a(CaPaEBR)ebrary10056911 035 $a(SSID)ssj0000112177 035 $a(PQKBManifestationID)11138792 035 $a(PQKBTitleCode)TC0000112177 035 $a(PQKBWorkID)10087743 035 $a(PQKB)10161676 035 $a(MiAaPQ)EBC3376635 035 $a(Au-PeEL)EBL3376635 035 $a(CaPaEBR)ebr10056911 035 $a(OCoLC)697473560 035 $a(EXLCZ)99110986584752254 100 $a19971230d1998 uy 0 101 0 $aeng 135 $aurcn||||||||| 181 $ctxt 182 $cc 183 $acr 200 00$aBiomedical models and resources $ecurrent needs and future opportunities /$fCommittee on New and Emerging Models in Biomedical and Behavioral Research, Institute for Laboratory Animal Research, Commission on Life Sciences, National Research Council 205 $a1st ed. 210 $aWashington, D.C. $cNational Academy Press$d1998 215 $a1 online resource (84 p.) 300 $aBibliographic Level Mode of Issuance: Monograph 311 $a0-309-06035-4 320 $aIncludes bibliographical references. 327 $aBiomedical Models and Resources -- Copyright -- Preface -- Contents -- Executive Summary -- 1 Introduction -- THE COMMITTEE'S CHARGE AND APPROACH -- STRUCTURE OF THE REPORT -- 2 Biomedical Model Definition -- 3 Essential and Emerging Research Fields and Technologies -- FUNCTIONAL GENOMICS -- AGING -- BEHAVIOR AND NEUROBIOLOGY -- COMPLEX DISEASE -- MODEL DISCOVERY -- MATHEMATICAL MODELLING, COMPUTATIONAL SIMULATIONS, AND SCIENTIFIC DATABASES -- EMERGING AND RE-EMERGING INFECTIOUS DISEASES -- 4 Overriding Issues -- ISSUES WITHIN THE PURVIEW OF NCRR -- MAINTENANCE AND PRESERVATION -- FACILITY INFRASTRUCTURE -- AVAILABILITY OF EXPERTISE AND TRAINING -- INFECTIOUS DISEASE, ANIMAL HEALTH -- ISSUES BEYOND THE SCOPE OF NCRR -- CIRCULAR A-21 -- INTELLECTUAL PROPERTY RIGHTS -- DATABASES AND CONFIDENTIALITY -- 5 Recommendations -- ENCOURAGE AND SUPPORT RESEARCH DIRECTED AT IMPROVING RESEARCH ANIMALUTILITY, AVAILABILITY, HEALTH, WELFARE, AND MAINTENANCE -- LABORATORY ANIMAL HEALTH AND WELFARE -- Diagnosis and infectious disease -- Behavior -- IMPROVED ANIMAL ACQUISITION, MAINTENANCE, PROPAGATION AND PRESERVATION -- DEVELOPMENT OF GENETIC MAPS FOR ADDITIONAL MODEL SPECIES -- INSTRUMENTATION DEVELOPMENT AND MINIATURIZATION -- CREATE A NATIONAL NETWORK OF COMPARATIVE MEDICAL EXPERTISE -- TO SUPPORT NIH RESEARCH EFFORTS ON ANIMAL MODELS, SUCH AS PHENOTYPICAND GENOTYPIC ASSESSMENT AND DISEASE DIAGNOSTICS -- TO PROMOTE MULTIDISCIPLINARY INTERACTION -- CREATE A NATIONAL NETWORK OF INTEGRATIVE-BIOLOGY EXPERTISE THAT CANSERVE THE ENTIRE BIOMEDICAL RESEARCH COMMUNITY -- ACADEMIC INFRASTRUCTURE FOR INTEGRATIVE BIOLOGY RELATED TO ANIMALS -- MATHEMATICAL MODELLING, COMPUTATIONAL SIMULATIONS, AND SCIENTIFIC DATABASES -- Encouragement and Facilitation of Interdisciplinary Research -- Development and Dissemination of Appropriate Information Technologies. 327 $aDevelopment and Maintenance of Databases, Interdisciplinary Modelling and Informatics Issues. The Si ... -- INCREASE THE COMMITMENT AND RESOURCES FOR CONSTRUCTING AND RENOVATINGANIMAL RESEARCH FACILITIES -- REINVIGORATE AND EXPAND TRAINING OPPORTUNITIES IN INTEGRATIVE BIOLOGY -- OBTAIN PROGRAM GUIDANCE FROM THE SCIENTIFIC COMMUNITY -- USE EXISTING MECHANISMS BETTER -- FUND INDEPENDENT EXTERNAL ADVISORY GROUPS EVERY FOUR YEARS -- 6 Criteria -- References -- APPENDIXES -- APPENDIX A SURVEY INSTRUMENT -- Future Trends in Biomedical Research -- BIOMEDICAL MODELS FOR THE NEXT 5-10 YEARS -- CURRENT MODELS WAITING TO BE DEVELOPED -- IDENTIFYING NEW BIOLOGICAL MODELS -- APPENDIX B BIOGRAPHICAL SKETCHES OF AUTHORING COMMITTEE -- WORKSHOPAGENDA -- AND WORKSHOP PARTICIPANTS -- APPENDIX C Models for Biomedical Research -- What Is a Model? -- REFERENCES -- APPENDIX D COMPARATIVE MEDICAL SCIENTISTS' REPORT -- A. Biotechnology -- B. Specialized Facilities -- C. Diagnostics -- D. Informatics -- E. Training -- F. Administration -- G. Personnel -- H. Facilities. 606 $aAnimal experimentation$zUnited States 606 $aMedicine$xResearch$zUnited States 606 $aAnimal models in research$zUnited States 615 0$aAnimal experimentation 615 0$aMedicine$xResearch 615 0$aAnimal models in research 712 02$aInstitute for Laboratory Animal Research (U.S.).$bCommittee on New and Emerging Models in Biomedical and Behavioral Research. 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910812215603321 996 $aBiomedical models and resources$94042185 997 $aUNINA