LEADER 05100nam 2200553 450 001 9910828520003321 005 20230807213625.0 010 $a1-910190-06-3 035 $a(CKB)3710000000356552 035 $a(EBL)1977392 035 $a(SSID)ssj0001467543 035 $a(PQKBManifestationID)11865280 035 $a(PQKBTitleCode)TC0001467543 035 $a(PQKBWorkID)11517040 035 $a(PQKB)10654529 035 $a(MiAaPQ)EBC1977392 035 $a(MiAaPQ)EBC5897779 035 $a(EXLCZ)993710000000356552 100 $a20191011d2015 uy 0 101 0 $aeng 135 $aur|n|---||||| 181 $ctxt 182 $cc 183 $acr 200 00$aCorynebacterium glutamicum $efrom systems biology to biotechnological applications /$fedited by Andreas Burkovski 210 1$aNorfolk, England :$cCaister Academic Press,$d[2015] 210 4$dİ2015 215 $a1 online resource (210 p.) 300 $aDescription based upon print version of record. 311 $a1-910190-05-5 320 $aIncludes bibliographical references and index. 327 $aContents; Contributors; Current Books of Interest; Preface; 1: Trends in Corynebacterium glutamicum Research and Application; From glutamate producer to a biotechnology workhorse; Systems biology; Corynebacterium glutamicum as a synthetic biology platform; Corynebacterium glutamicum-based green technology; 2: Proteomics of Corynebacterium glutamicum; Introduction; Understanding Corynebacterium glutamicum physiology with proteomics: application examples; Methods of Corynebacterium glutamicum proteomics; Conclusion and outlook 327 $a3: Developing Interpretation of Intracellular Metabolism of Corynebacterium glutamicum by Using Flux Analysis TechnologyIntroduction; Understanding the physiology of Corynebacterium glutamicum lysine production and glutamate production through conventional metabolic flux analysis; Fractional 13C enrichment-based metabolic flux analysis; Improvement in metabolic flux analysis precision; Conclusion; 4: Growth and Production Capabilities of Corynebacterium glutamicum: Interrogating a Genome-scale Metabolic Network Model; Introduction; The metabolic network of Corynebacterium glutamicum 327 $aStoichiometric modelling fundamentalsModel validation; Predicting production capabilities for amino acids; Uncertainties in metabolic network models; Metabolic flux analysis; Conclusions; 5: Metabolic Engineering of Corynebacterium glutamicum for Alternative Carbon Source Utilization; Introduction; Engineering of Corynebacterium glutamicum for alternative carbon sources; Complex carbon sources; Summary and outlook; 6: Manipulation of Nitrogen Metabolism and Alternative Nitrogen Sources for Corynebacterium glutamicum; Ammonium assimilation in Corynebacterium glutamicum 327 $aRegulation of nitrogen metabolismManipulation of nitrogen metabolism for amino acid production; Overexpression, deletion and heterologous expression of glutamate dehydrogenase; Overexpression of glutamine synthetases; Influence of glutamate synthase on L-glutamate biosynthesis; Changing ammonium assimilation and amino acid production by manipulation of ?-ketoglutarate supply; Influence of ammonium and glutamate transport systems on amino acid production; Manipulation of nitrogen regulation: influences on metabolite pools; Assimilation of alternative nitrogen sources; Concluding remarks 327 $a7: Transport, Degradation and Assimilation of Aromatic Compounds and their Regulation in Corynebacterium glutamicum Introduction; What do the Corynebacterium glutamicum genomes predict for degradation and assimilation of aromatic compounds?; Corynebacterium glutamicum grows on various aromatic compounds; Physiological adaptation of Corynebacterium glutamicum growing on aromatic compounds compared with carbohydrates; Uptake and transport of aromatic compounds in Corynebacterium glutamicum; Aromatic compounds degraded via protocatechuate branch of the ?-ketoadipate pathway 327 $aAromatic compounds degraded via the catechol branch of the ?-ketoadipate pathway 330 $aCorynebacterium glutamicum is most widely known for its role in the industrial production of L-glutamate and L-lysine and as a platform organism for the production of a variety of fine chemicals, biofuels and polymers. The organism's accessibility to genetic manipulation has resulted in a wealth of data on its metabolism and regulatory networks; this in turn makes C. glutamicum the model organism of choice in white biotechnology. A key development in recent years has been the engineering of C. glutamicum to utilize a broader spectrum of carbon sources (e.g. glycerol, galactose and pentose suga 606 $aCorynebacterium glutamicum$xMetabolism 615 0$aCorynebacterium glutamicum$xMetabolism. 676 $a579.373 702 $aBurkovski$b Andreas 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910828520003321 996 $aCorynebacterium glutamicum$91944960 997 $aUNINA LEADER 03000nam 2200757 a 450 001 9910811994103321 005 20200520144314.0 010 $a9786611450250 010 $a9781281450258 010 $a1281450251 010 $a9780470385043 010 $a0470385049 010 $a9780470384824 010 $a0470384824 035 $a(CKB)1000000000687200 035 $a(EBL)353504 035 $a(OCoLC)437219631 035 $a(SSID)ssj0000213015 035 $a(PQKBManifestationID)11173627 035 $a(PQKBTitleCode)TC0000213015 035 $a(PQKBWorkID)10140635 035 $a(PQKB)11300812 035 $a(MiAaPQ)EBC353504 035 $a(Au-PeEL)EBL353504 035 $a(CaPaEBR)ebr10296761 035 $a(CaONFJC)MIL145025 035 $a(OCoLC)37590236 035 $a(FINmELB)ELB178509 035 $a(Perlego)2765123 035 $a(EXLCZ)991000000000687200 100 $a19970428d1997 uy 0 101 0 $aeng 135 $aur|n|---||||| 181 $ctxt 182 $cc 183 $acr 200 00$aNutraceuticals $edesigner foods III garlic, soy and licorice /$fedited by Paul A. Lachance 205 $a1st ed. 210 $aTrumbull, Conn. $cFood & Nutrition Press, Inc.$dc1997 215 $a1 online resource (398 p.) 300 $aDescription based upon print version of record. 311 08$a9780917678400 311 08$a0917678400 320 $aIncludes bibliographical references and index. 327 $asection 1. Perspectives -- section 2. The chemical and biological principles of designer foods -- section 3. Phytopharmacology of garlic food forms -- section 4. Phytopharmacology of soy food forms -- section 5. Phytopharmacology of licorice food forms -- section 6. Bridging the gaps in knowledge for designer food applications. 330 $aPhytochemicals are components acting individually, additively or synergistically, usually as a component of whole food, that have the characteristics of providing protective, preventative and possibly curative roles in the pathogenesis of cancer and other chronic disease progressions. Nutraceutical is a term used to describe beneficial phytochemicals. The mechanisms of action of nutraceuticals may be one of several. Free radical scavenger and antioxidant nutraceuticals can nullify damage by any number of biochemical mechanisms, but some also exert benefit by enhancing immune function. A 517 3 $aDesigner foods III garlic, soy, and licorice 606 $aNutrition 606 $aLicorice (Plant) 606 $aSoyfoods 606 $aGarlic 606 $aFunctional foods 615 0$aNutrition. 615 0$aLicorice (Plant) 615 0$aSoyfoods. 615 0$aGarlic. 615 0$aFunctional foods. 676 $a615.8/54 701 $aLachance$b Paul A$0868425 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910811994103321 996 $aNutraceuticals$91938553 997 $aUNINA