LEADER 03014oam 2200409z- 450 001 9910811443003321 005 20210111164358.0 010 $a0-309-45029-2 010 $a0-309-45027-6 035 $a(CKB)3710000001064498 035 $a(MiAaPQ)EBC4806755 035 $a(EXLCZ)993710000001064498 100 $a20170306c2017uuuu -u- - 101 0 $aeng 200 10$aDeveloping multimodal therapies for brain disorders $eproceedings of a workshop /$fLisa Bain, Noam I. Keren, and Clare Stroud, rapporteurs ; Forum on Neuroscience and Nervous System Disorders, Board on Health Sciences Policy, Health and Medicine Division, the National Academies of Sciences, Engineering, Medicine 210 $cNational Academies Press 311 $a0-309-45026-8 327 $aIntroduction -- Multimodal therapy: overview of principles, barriers, and opportunities -- Exploring the state of the science -- Exploring the state of the science -- Regulatory and reimbursement considerations -- Trial designs to establish efficacy and safety in multimodal therapies -- Developing multimodal therapies: practical considerations relating to industry -- Role of research funders in multimodal therapy development -- Appendix A: References -- Appendix B: Workshop agenda -- Appendix C: Registered participants. 330 $a"Multimodal therapy approaches that combine interventions aimed at different aspects of disease are emerging as potential--and perhaps essential--ways to enhance clinical outcomes for patients with psychiatric and neurological disorders. In order to examine the general principles underlying multimodal therapies and to explore challenges, potential barriers, and opportunities for their development, the National Academies of Sciences, Engineering, and Medicine convened a workshop in June 2016. Participants explored scientific, clinical, regulatory, and reimbursement issues related to multimodal approaches and potential opportunities to enhance clinical outcomes for individuals with nervous system disorders. This publication summarizes the presentations and discussions from the workshop"--Publisher's description. 606 $aBrain$xDiseases$xAdjuvant treatment$vCongresses 606 $aCombined modality therapy$vCongresses 606 $aCombined Modality Therapy 606 $aBrain Diseases$xtherapy 615 0$aBrain$xDiseases$xAdjuvant treatment 615 0$aCombined modality therapy 615 12$aCombined Modality Therapy. 615 12$aBrain Diseases$xtherapy. 676 $a616.8/046 700 $aBain$b Lisa J.$01603466 702 $aKeren$b Noam I. 702 $aStroud$b Clare 712 02$aNational Academies of Sciences, Engineering, and Medicine (U.S.).$bForum on Neuroscience and Nervous System Disorders, 712 12$aMultimodal Therapies for Brain Disorders (Workshop)$f(2016 :$eWashington, D.C.),$bauthor. 906 $aBOOK 912 $a9910811443003321 996 $aDeveloping multimodal therapies for brain disorders$93927844 997 $aUNINA