LEADER 05368nam 2200697Ia 450 001 9910811052603321 005 20230130193347.0 010 $a1-78402-376-0 010 $a0-12-385943-3 035 $a(CKB)2670000000237701 035 $a(EBL)1031881 035 $a(OCoLC)818815074 035 $a(SSID)ssj0000767246 035 $a(PQKBManifestationID)12350170 035 $a(PQKBTitleCode)TC0000767246 035 $a(PQKBWorkID)10741336 035 $a(PQKB)10870030 035 $a(Au-PeEL)EBL1031881 035 $a(CaPaEBR)ebr10604671 035 $a(CaONFJC)MIL967277 035 $z(PPN)18256519X 035 $a(PPN)170603911 035 $a(FR-PaCSA)88812219 035 $a(MiAaPQ)EBC1031881 035 $a(EXLCZ)992670000000237701 100 $a20050413d2012 uy 0 101 0 $aeng 135 $aur|n|---||||| 181 $ctxt 182 $cc 183 $acr 200 00$aHandbook of stem cells$hVolume 2$iAdult and fetal stem cells /$feditors, Robert P. Lanza, Anthony Atala 205 $a2nd ed. 210 $aAmsterdam ;$aBoston $cElsevier / AP$d2012 215 $a1 online resource (1076 p.) 300 $aDescription based upon print version of record. 311 $a0-12-385942-5 320 $aIncludes bibliographical references and index. 327 $ae9780123859426v1; Front Cover; Handbook of Stem Cells: Volume 1: Pluripotent Stem Cells; REFERENCES; REFERENCES; REFERENCES; Chapter3 - Pluripotential Stem Cells from Vertebrate Embryos: Present Perspective and Future Challenges; Chapter16 - Primordial Germ Cells in Mouse and Human; Chapter61 - Neural Stem Cells - Therapeutic Applications in Neurodegenerative Diseases; Chapter78 - Histogenesis in Three-Dimensional Scaffolds; Chapter80 - Ethical Considerations; REFERENCES; REFERENCES; REFERENCES; FURTHER READING; Preface 327 $aChapter5 - The Molecular Circuitry Underlying Pluripotency in Embryonic Stem Cells and iPS CellsChapter27 - Homologous Recombination in Human Embryonic Stem Cells; MOLECULES THAT ORGANIZE CELLS; THE EMT TRANSCRIPTIONAL PROGRAM; MOLECULAR CONTROL OF THE EMT; REPAIR OF MYOCARDIAL DAMAGE BY RESIDENT PRIMITIVE CELLS; CONCLUSION; ACKNOWLEDGMENTS; STRUCTURAL COMPONENTS OF THE NICHE; GUIDELINES FROM THE NATIONAL ACADEMIES; MAMMALIAN TESTIS; HEMATOPOIETIC SYSTEM; Chapter9 - Cell Cycle Regulators in Stem Cells; INTRODUCTION; INTRODUCTION; INTRODUCTION; DEFINITIONS; Contributors 327 $aChapter50 - Peripheral Blood Stem CellsINTRODUCTION; Chapter63 - Sensory Epithelium of the Eye and Ear; ROLES OF P27 IN STEM CELL REGULATION; IMPLICATIONS FOR REGENERATIVE MEDICINE; MEDICINAL SIGNALING CELLS; SUMMARY; PANCREATIC ACINAR CELL TRANSDIFFERENTIATION; REFERENCES; REFERENCES; Chapter10 - Cell Fusion and the Differentiated State; Chapter35 - Potential of ES Cell Differentiation Culture for Vascular Biology; Chapter68 - Pancreatic Stem Cells; ACKNOWLEDGMENTS; REFERENCES; CONCLUSION; REFERENCES; DEDIFFERENTIATION AS A PREREQUISITE FOR TRANSDIFFERENTIATION 327 $aGENETIC MODIFICATIONS OF HESC-DERIVED PROGENIESSUMMARY; CHALLENGES; TECHNICAL ASPECTS OF SOMATIC NUCLEAR TRANSFER; POSTNATAL TISSUE-SPECIFIC STEM CELLS - ARE SOME MORE THAN MULTIPOTENT?; TYPES AND SOURCE OF STEM CELLS IN THE PERIPHERAL BLOOD; THE BULGE AS A RESIDENCE OF EPITHELIAL SKIN STEM CELLS; BONE; EPIGENETIC REPROGRAMMING; PROMOTING HEMATOPOIETIC ENGRAFTMENT WITH STAT5 AND HOXB4; GENE THERAPY USING NEURAL STEM CELLS; REFERENCES; REFERENCES; REFERENCES; INTRODUCTION; INTRODUCTION; SYNTHETIC TRANSCRIPTION FACTORS FOR TARGETED GENE REGULATION 327 $aPLURIPOTENT STEM CELLS FOR FUTURE CELL-BASED THERAPIESChapter14 - Differentiation in Early Development; PREIMPLANTATION DEVELOPMENT; Chapter67 - Stem Cells in the Gastrointestinal Tract; REFERENCES; REFERENCES; Chapter15 - Developmental Mechanisms of Regeneration; INTRODUCTION; Chapter22 - Embryonic Stem Cells: Derivation and Properties; Chapter25 - Genetic Approaches in Human Embryonic Stem Cells and their Derivatives: Prospects for Regenerative Medicine; INTRODUCTION; Chapter54 - Stem Cells and Heart Disease; CHOOSING LIFE; INTRODUCTION; INTRODUCTION; EMBRYONIC GERM CELLS; ACKNOWLEDGMENTS 327 $aBASIC FIBROBLAST GROWTH FACTOR (FGF-2) AND KNOCKOUT SERUM REPLACER 330 $aNew discoveries in the field of stem cells increasingly dominate the news and scientific literature revealing an avalanche of new knowledge and research tools that are producing therapies for cancer, heart disease, diabetes, and a wide variety of other diseases that afflict humanity. The Handbook of Stem Cells integrates this exciting area of life science, combining in two volumes the requisites for a general understanding of adult and embryonic stem cells. Organized in two volumes entitled Pluripotent Stem Cells & Cell Biology and Adult & Fetal Stem Cells, this work contains contributions 606 $aStem cells 606 $aTissue engineering 615 0$aStem cells. 615 0$aTissue engineering. 676 $a616.02774 676 $a616/.02774 676 $a616.02774 701 $aLanza$b Robert$f1956-$01242243 701 $aAtala$b Anthony$f1958-$0523426 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910811052603321 996 $aHandbook of stem cells$94087236 997 $aUNINA