LEADER 02684nam 2200625 a 450 001 9910809901503321 005 20240417004053.0 010 $a0-309-17817-7 010 $a1-281-30023-3 010 $a9786611300234 010 $a0-309-11013-0 035 $a(CKB)1000000000714260 035 $a(SSID)ssj0000279034 035 $a(PQKBManifestationID)11210640 035 $a(PQKBTitleCode)TC0000279034 035 $a(PQKBWorkID)10259467 035 $a(PQKB)10930698 035 $a(MiAaPQ)EBC3378332 035 $a(Au-PeEL)EBL3378332 035 $a(CaPaEBR)ebr10225174 035 $a(CaONFJC)MIL130023 035 $a(OCoLC)923278378 035 $a(EXLCZ)991000000000714260 100 $a20080623d2008 uy 0 101 0 $aeng 135 $aurcn||||||||| 181 $ctxt 182 $cc 183 $acr 200 00$aEmerging safety science $eworkshop summary /$fSally Robinson, Robert Pool, and Robert Giffin [rapporteurs] ; Forum on Drug Discovery, Development, and Translation, Board on Health Sciences Policy, Institute of Medicine of the National Academies 205 $a1st ed. 210 $aWashington, D.C. $cNational Academies Press$dc2008 215 $axvi, 134 p. $cill. (some col.) 300 $aWorkshop held April 23-24, 2007 in Silver Spring, MD. 311 $a0-309-11012-2 320 $aIncludes bibliographical references (p. 115-116). 327 $aFront Matter -- Reviewers -- Preface -- Contents -- Tables and Figures -- 1 Introduction -- 2 Investigative Toxicology: The State of the Art -- 3 Screening Technologies I: Human Cell-Based Approaches -- 4 Screening Technologies II: Toxicogenomics -- 5 Screening Technologies III: Metabolomics -- 6 Screening Technologies IV: Pharmacogenetics -- 7 Qualifying Biomarkers -- 8 Pharmacovigilance -- 9 Integration -- 10 The Future of Safety Science -- References -- Appendixes -- Appendix A: Workshop Agenda -- Appendix B: Speaker Biographies. 606 $aDrugs$zUnited States$xSafety measures$vCongresses 606 $aPharmaceutical biotechnology$zUnited States$vCongresses 606 $aDrugs$zUnited States$xDesign$vCongresses 615 0$aDrugs$xSafety measures 615 0$aPharmaceutical biotechnology 615 0$aDrugs$xDesign 676 $a615/.10289 701 $aRobinson$b Sally$0620917 701 $aPool$b Robert$0288454 701 $aGiffin$b Robert B$01653478 712 02$aInstitute of Medicine (U.S.).$bForum on Drug Discovery, Development, and Translation. 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910809901503321 996 $aEmerging safety science$94004809 997 $aUNINA