LEADER 03525nam 2200601 a 450 001 9910809103103321 005 20200520144314.0 010 $a1-280-75153-3 010 $a9786610751532 010 $a0-08-046908-6 035 $a(CKB)1000000000364151 035 $a(EBL)285783 035 $a(OCoLC)476037278 035 $a(SSID)ssj0000206027 035 $a(PQKBManifestationID)11189284 035 $a(PQKBTitleCode)TC0000206027 035 $a(PQKBWorkID)10212795 035 $a(PQKB)11223366 035 $a(MiAaPQ)EBC285783 035 $a(EXLCZ)991000000000364151 100 $a20080905d2007 uy 0 101 0 $aeng 135 $aur|n|---||||| 181 $ctxt 182 $cc 183 $acr 200 00$aImmunology /$fedited by James G. Fox ... [et al.] 205 $a2nd ed. 210 $aAmsterdam $cElsevier$dc2007 215 $a1 online resource (395 p.) 225 1 $aMouse in biomedical research ;$vv. 4 225 1 $aAmerican College of Laboratory Animal Medicine series 300 $aDescription based upon print version of record. 311 $a0-12-369458-2 320 $aIncludes bibliographies and indexes. 327 $aFront Cover; The Mouse in Biomedical Research: Immunology; Copyright Page; Table of Contents; List of Reviewers; List of Contributors; Foreword; Preface; Overview; Chapter 1. The Molecular Basis of Lymphoid Architecture in the Mouse; Chapter 2. The Biology of Toll-Like Receptors in Mice; Chapter 3. Genomic Organization of the Mouse Major Histocompatibility Complex; Chapter 4. Some Biological Features of Dendritic Cells in the Mouse; Chapter 5. Mouse Models Revealed the Mechanisms for Somatic Hypermutation and Class Switch Recombination of Immunoglobulin Genes 327 $aChapter 6. Mouse Natural Killer Cells: Function and ActivationChapter 7. Cytokine-Activated JAK-STAT Signaling in the Mouse Immune System; Chapter 8. Signal Transduction Events Regulating Integrin Function and T Cell Migration in the Mouse; Chapter 9. Mouse Models of Negative Selection; Chapter 10. Peripheral Tolerance of T Cells in the Mouse; Chapter 11. The Genetics of Mouse Models of Systemic Lupus; Chapter 12. Inhibitory Receptors and Autoimmunity in the Mouse; Chapter 13. Mouse Models of Immunodeficiency; Chapter 14. Mouse Models to Study the Pathogenesis of Allergic Asthma 327 $aChapter 15. The Mouse Trap: How Well Do Mice Model Human Immunology?Index; Colour Plates 330 $aImmunology, the third volume in the four volume set, The Mouse in Biomedical Research, is a completely new addition to this series, dedicated to mouse immunology. It is based on the vast body of knowledge which has made the mouse the model of choice when studying immunity in man. Arguably more is known about the immune system in mice than any other species except man. In large part this is due to the power of genetic engineering to delineate molecular mechanisms. In this volume we present an Overview to mouse immunology, including both the innate and adaptive immune systems, foll 410 0$aMouse in biomedical research ;$vv. 4. 410 0$aAmerican College of Laboratory Animal Medicine series. 606 $aMice as laboratory animals 615 0$aMice as laboratory animals. 676 $a616.027333 676 $a616/.027333 701 $aFox$b James G$01612434 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910809103103321 996 $aImmunology$94196963 997 $aUNINA