LEADER 04981nam 2200757 450 001 9910808859703321 005 20230803022425.0 010 $a3-11-028495-2 024 7 $a10.1515/9783110284959 035 $a(CKB)2550000001157362 035 $a(EBL)1121614 035 $a(SSID)ssj0001041414 035 $a(PQKBManifestationID)11572161 035 $a(PQKBTitleCode)TC0001041414 035 $a(PQKBWorkID)11044888 035 $a(PQKB)10903604 035 $a(MiAaPQ)EBC1121614 035 $a(DE-B1597)176266 035 $a(OCoLC)1002232145 035 $a(OCoLC)1004879684 035 $a(OCoLC)1011463544 035 $a(OCoLC)864908895 035 $a(OCoLC)979745435 035 $a(OCoLC)984688422 035 $a(OCoLC)987934867 035 $a(OCoLC)992471976 035 $a(OCoLC)999366701 035 $a(DE-B1597)9783110284959 035 $a(Au-PeEL)EBL1121614 035 $a(CaPaEBR)ebr10811260 035 $a(CaONFJC)MIL540408 035 $a(EXLCZ)992550000001157362 100 $a20130205h20132013 uy 0 101 0 $aeng 135 $aur|n|---||||| 181 $ctxt 182 $cc 183 $acr 200 00$aRNA structure and folding $ebiophysical techniques and prediction methods /$fedited by Dagmar Klostermeier, Christian Hammann 210 1$aBerlin :$cWalter de Gruyter GmbH & Company,$d[2013] 210 4$d©2013 215 $a1 online resource (432 p.) 300 $aIncludes index. 311 $a3-11-028459-6 311 $a1-306-09157-8 327 $t Frontmatter -- $tPreface -- $tList of contributing authors -- $tContents -- $t1. Optical spectroscopy and calorimetry / $rKlostermeier, Dagmar / Hammann, Christian -- $t2. Footprinting methods for mapping RNA-protein and RNA-RNA interactions / $rDuval, Mélodie / Romilly, Cedric / Helfer, Anne-Catherine / Fuchsbauer, Olivier / Romby, Pascale / Marzi, Stefano -- $t3. Chemical approaches to the structural investigation of RNA in solution / $rHelm, Mark -- $t4. Bioorthogonal modifications and cycloaddition reactions for RNA chemical biology / $rHöbartner, Claudia / Büttner, Lea / Javadi-Zarnaghi, Fatemeh -- $t5. Analysis of RNA conformation using comparative gel electrophoresis / $rLilley, David M. J. -- $t6. Virus RNA structure deduced by combining X-ray diffraction and atomic force microscopy / $rMcPherson, Alexander -- $t7. Investigating RNA structure and folding with optical tweezers / $rBercy, Mathilde / Mangeol, Pierre / Bizebard, Thierry / Tanner, N. Kyle / Banroques, Josette / Bockelmann, Ulrich -- $t8. Fluorescence resonance energy transfer as a tool to investigate RNA structure and folding / $rGubaev, Airat / Klostermeier, Dagmar -- $t9. RNA studies by small angle X-ray scattering in solution / $rKikhney, Alexey G. / Doniach, Sebastian / Svergun, Dmitri I. -- $t10 Integrative structure-function analysis of large nucleoprotein complexes / $rMénétret, Jean-François / Khatter, Heena / Simonetti, Angelita / Orlov, Igor / Myasnikov, Alexander G. / Venkatasubramanian, Srividhya Krishnagiri / Manicka, Sankar / Torchy, Morgan / Mohideen, Kareem / Humm, Anne-Sophie / Hazemann, Isabelle / Urzhumtsev, Alexandre / Klaholz, Bruno P. -- $t11 Structure and conformational dynamics of RNA determined by pulsed EPR / $rKrstic, Ivan / Marko, Andriy / Grytz, Claudia M. / Endeward, Burkhard / Prisner, Thomas F. -- $t12. NMR-based characterization of RNA structure and dynamics / $rMozes, Christina R. / Hennig, Mirko -- $t13. Crystallization of RNA for structure determination by X-ray crystallography / $rFerré-D'Amaré, Adrian R. -- $t14. RNA structure prediction / $rSteger, Gerhard / Giegerich, Robert -- $t15. Analyzing, searching, and annotating recurrent RNA three-dimensional motifs / $rPetrov, Anton I. / Sweeney, Blake A. / Leontis, Neocles B. -- $tIndex 330 $aWhile structure-function relationships of proteins have been studied for a long time, structural studies of RNA face additional challenges. Nevertheless, with the continuous discovery of novel RNA molecules with key cellular functions and of novel pathways and interaction networks, the need for structural information of RNA is still increasing. This volume provides an introduction into techniques to assess structure and folding of RNA. Each chapter explains the theoretical background of one technique, and illustrates possibilities and limitations in selected application examples. 606 $aProtein folding 606 $aRNA 610 $aBiophysics. 610 $aExperimental Techniques. 610 $aPrediction Methods. 610 $aRNA. 615 0$aProtein folding. 615 0$aRNA. 676 $a572.8/8 686 $aWD 5355$2rvk 701 $aHammann$b Christian$01697614 701 $aKlostermeier$b Dagmar$01697615 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910808859703321 996 $aRNA structure and folding$94078477 997 $aUNINA