LEADER 03708nam 22006254a 450 001 9910808219803321 005 20200520144314.0 010 $a600-00-0515-6 010 $a9786610505364 010 $a1-280-50536-2 010 $a1-60129-451-4 035 $a(CKB)111087027618448 035 $a(OCoLC)53017729 035 $a(CaPaEBR)ebrary10116449 035 $a(SSID)ssj0000218144 035 $a(PQKBManifestationID)11217602 035 $a(PQKBTitleCode)TC0000218144 035 $a(PQKBWorkID)10214391 035 $a(PQKB)11091629 035 $a(MiAaPQ)EBC267521 035 $a(Au-PeEL)EBL267521 035 $a(CaPaEBR)ebr10116449 035 $a(CaONFJC)MIL50536 035 $a(OCoLC)437171326 035 $a(EXLCZ)99111087027618448 100 $a20011105d2002 uy 0 101 0 $aeng 135 $aurcn||||||||| 181 $ctxt 182 $cc 183 $acr 200 10$aParkinson's disease /$fedited by E. Ronken and G.J.M. van Scharrenburg 205 $a1st ed. 210 $aAmsterdam ;$aWashington, DC $cIOS Press$dc2002 215 $a1 online resource (168 p.) 225 1 $aSolvay Pharmaceuticals Conferences,$x1566-7685 ;$vv. 1 300 $a"The First Solvay Pharmaceuticals Conference on "Parkinson's Disease" was held in Como from October 25 to 27, 2000"--Pref. 311 $a1-58603-207-0 311 $a0-585-45882-0 320 $aIncludes bibliographical references and index. 327 $aCover -- Title page -- Preface -- List of Contributors -- Contents -- Conference Preface -- Key-note lecture - Movement Disorders: An Overview -- Part I: Parkinson's Disease - Symptoms, Models and Treatment -- Neurochemical Changes in Parkinson's Disease -- Psychosis and Depression in Parkinson's Disease -- Experimental Models of Parkinson's Disease -- SLV308: A Novel Antiparkinsonian Agent with Antidepressant and Anxiolytic Properties -- Adenosine A[sub(2A)] Receptor Antagonists and Parkinson's Disease -- Part II: Understanding and Influencing Neuro-Degeneration -- Bioenergetics in Neurodegeneration -- Neuronal Cell Death and Apoptosis in Neurodegenerative Diseases -- Animal Models of Neurodegeneration in Parkinson's Disease -- Parkinsonian Features of the Ataxia-Telangiectasia and of the Atm-Deficient Mouse -- Neuroprotection in Parkinson's Disease through Selective Gene Induction -- Part III: Towards Neuroprotective Efficacy -- The RET-Dependent Neuroprotective Effects of GDNF are Mediated by Activation of Proteinkinase B (PKB)/AKT -- An Immortalized Neuronal Cell Line Derived from the Substantia Nigra of an Adult Rat: Application to Cell Transplant Therapy -- Lentiviral Vector Delivery of GDNF in Primate Models of Parkinson's Disease Prevents Neurodegeneration -- Design of Clinical Studies for Neuroprotective Efficacy -- Regulation of Glial Cell Line-Derived Neurotrophic Factor (GDNF) for Dopamine Conservation in Models for Parkinson's Disease -- Concluding Remarks -- Author Index -- A -- B -- C -- D -- E -- F -- H -- J -- K -- L -- M -- N -- O -- P -- R -- S -- T -- V -- W. 330 $aThis volume contains the proceedings of the first Solvay Pharmaceuticals Research Symposium, and is dedicated to Parkinson's disease. It provides an update of clinical and preclinical research. 410 0$aSolvay Pharmaceuticals Conferences ;$vv. 1. 606 $aParkinson's disease$vCongresses 615 0$aParkinson's disease 676 $a616.8/33 701 $aRonken$b E$01674979 701 $aScharrenburg$b G. J. M. van$01674980 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910808219803321 996 $aParkinson's disease$94040139 997 $aUNINA