LEADER 05576nam 2200685 450 001 9910807752803321 005 20230803220527.0 010 $a1-118-59063-5 010 $a1-118-59060-0 010 $a1-118-59061-9 035 $a(CKB)2550000001166756 035 $a(EBL)1574351 035 $a(SSID)ssj0001098698 035 $a(PQKBManifestationID)12457507 035 $a(PQKBTitleCode)TC0001098698 035 $a(PQKBWorkID)11056332 035 $a(PQKB)11571745 035 $a(MiAaPQ)EBC1574351 035 $a(Au-PeEL)EBL1574351 035 $a(CaPaEBR)ebr10814726 035 $a(CaONFJC)MIL548134 035 $a(OCoLC)864746032 035 $a(EXLCZ)992550000001166756 100 $a20131217d2014 uy 0 101 0 $aeng 135 $aur|n|---||||| 181 $ctxt 182 $cc 183 $acr 200 00$aDermatologic principles and practice in oncology $econditions of the skin, hair, and nails in cancer patients /$fedited by Mario E. Lacouture ; cover design by Matt Kuhns 210 1$aHoboken, New Jersey :$cWiley-Blackwell,$d2014. 210 4$dİ2014 215 $a1 online resource (442 p.) 300 $aDescription based upon print version of record. 311 $a0-470-62188-5 311 $a1-306-16883-X 320 $aIncludes bibliographical references at the end of each chapters and index. 327 $aCover; Title page; Copyright page; Contents; List of Contributors; Preface; 1: Dermatology and Oncology; 1: Epidemiology and Burden of Disease; Introduction; Dermatologic health in cancer patients and survivors; Financial burden; Health-related quality of life; Dosing of chemotherapy; Conclusions; References; Appendix 1.1 Anticancer agents and associated adverse events affecting the skin, mucosa, hair, and nails. Based on data from Litt JZ, 2009 [8].; 2: The History of Supportive Oncodermatology; Evolution of anticancer therapeutics 327 $aSpectrum of dermatologic adverse events stemming from conventional cytotoxic chemotherapy agentsRadiation and surgery-induced mucocutaneous toxicities; Mucocutaneous toxicities induced by novel targeted agents; Emergence of supportive oncodermatology and future directions; References; 3: Structure and Function of the Integumentary System and the Dermatology Lexicon; Introduction; Skin; Epidermis; Dermal-epidermal junction; Dermis; Vasculature; Nerves; Subcutaneous tissue; Appendages; Eccrine sweat glands; Apocrine sweat glands; Sebaceous glands; Hair; Nails; Morphology; Raised lesions; Papule 327 $aPlaqueNodule; Cyst; Wheal; Depressed lesions; Erosion; Ulcer; Atrophy; Poikiloderma; Flat lesions; Macule; Patch; Sclerosis; Erythema; Erythroderma; Fluid-filled lesions; Vesicle and bulla; Pustule; Furuncle; Abscess; Surface changes; Scale; Crust; Eschar; Purpura and vascular lesions; Purpura; Infarct; Shape, configuration, arrangement, and distribution of lesions; Conclusions; 4: Types of Dermatologic Reactions; Exanthematous eruptions; Urticarial eruptions; Lichenoid eruptions; Acneiform eruptions; Pustular eruptions (acute generalized exanthematous pustulosis); Bullous eruptions 327 $aDrug-induced vasculitisErythroderma; Approach to patients with suspected drug eruption; Step 1: Recognizing the morphology; Step 2: Associated symptoms and systemic involvement; Step 3: Histopathologic assessment; Step 4: Determining the offending drug; Conclusions; References; 5: Grading Dermatologic Adverse Events in Clinical Trials Using CTCAE v4.0; Common Terminology Criteria for Adverse Events; CTCAE grade scale; Attribution; Changes in CTCAE V4.0; Refined grading to correlate with clinical management; Alopecia; Rash acneiform; Skin hyperpigmentation; Split of embedded terms 327 $aRash maculopapularErythroderma; Bullous dermatitis; Nail discoloration, nail ridging, and nail loss; New adverse events; Hypertrichosis; Hypohidrosis; Lipohypertrophy; Periorbital edema; Moved to different SOC; Papulopustular rash; Rash pustular; Paronychia; CTCAE vs. MESTT; Conclusions; References; 6: Psychosocial Issues in Oncology: Clinical Management of Psychosocial Distress, Health-Related Quality of Life, and Special Considerations in Dermatologic Oncology; Psychosocial distress; Distress among dermatologic samples; Dermatologic AEs from cancer treatment; Risk factors for distress 327 $aClinical management of distress 330 $aThis is the first book to focus on frequent and frequently disabling side effects involving the skin, hair, and nails in cancer patients. It provides detailed descriptions of mechanism-of-action in all current oncology drugs and the clinical presentation and mechanisms underlying their dermatologic side effects, alongside carefully presented treatment recommendations, allowing physicians to significantly enhance their care of patients with cancer. Whereas existing oncology and dermatology textbooks only briefly deal with this topic, this resource offers dermatologists and other practitioners a 606 $aSkin$xDiseases$xEtiology 606 $aSkin$xDiseases$xPsychology 606 $aTumors$xComplications 615 0$aSkin$xDiseases$xEtiology. 615 0$aSkin$xDiseases$xPsychology. 615 0$aTumors$xComplications. 676 $a616.99/477 701 $aLacouture$b Mario E$0877731 701 $aKuhns$b Matt$01663029 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910807752803321 996 $aDermatologic principles and practice in oncology$94020054 997 $aUNINA