LEADER 05254nam 2200673 450 001 9910807748603321 005 20230803220529.0 010 $a1-118-65624-5 010 $a1-118-65612-1 010 $a1-118-65604-0 035 $a(CKB)2550000001165627 035 $a(EBL)1566395 035 $a(SSID)ssj0001059592 035 $a(PQKBManifestationID)11600369 035 $a(PQKBTitleCode)TC0001059592 035 $a(PQKBWorkID)11086419 035 $a(PQKB)11307830 035 $a(OCoLC)874967980 035 $a(MiAaPQ)EBC1566395 035 $a(DLC) 2013038006 035 $a(Au-PeEL)EBL1566395 035 $a(CaPaEBR)ebr10809693 035 $a(CaONFJC)MIL546895 035 $a(OCoLC)864505488 035 $a(EXLCZ)992550000001165627 100 $a20131209d2014 uy 0 101 0 $aeng 135 $aurcnu|||||||| 181 $ctxt 182 $cc 183 $acr 200 10$aDevelopmental genomics of ascidians /$fNoriyuki Satoh 210 1$aHoboken, New Jersey :$cWiley-Blackwell,$d2014. 210 4$dİ2014 215 $a1 online resource (339 p.) 300 $aDescription based upon print version of record. 311 $a1-118-65618-0 311 $a1-306-15644-0 320 $aIncludes bibliographical references at the end of each chapters and index. 327 $aCover; Title Page; Copyright; Dedication; Preface: Preface; Chapter 1: A Brief Introduction to Ascidians; 1.1 What are Ascidians?; 1.2 A Brief History of Research on Ascidian Embryos; Selected References; Chapter 2: The Development of Tadpole Larvae and Sessile Juveniles; 2.1 Embryogenesis and Tadpole Larvae; 2.2 Metamorphosis and Making a Sessile Juvenile; Selected References; Chapter 3: Genomics, Transcriptomics, and Proteomics; 3.1 The Genome of Ciona intestinalis; 3.2 Transcriptomics; 3.3 Proteomics; Selected References; Chapter 4: Research Tools 327 $a4.1 Experimental Manipulation of Embryonic Cells 4.2 Tracing of Cell Divisions; 4.3 Analyses of Gene Function; 4.4 Analyses of Regulatory Mechanisms of Specific Gene Expression; 4.5 Microarray; 4.6 Genetics, Mutagenesis, and Transgenesis; Selected References; Cold Spring Harbor Laboratory Protocols for Embryogenesis Studies; Chapter 5: The Function and Regulation of Maternal Transcripts; 5.1 Gene Expression Profiles Observed During the Ciona Life Cycle; 5.2 Oocyte Maturation, Fertilization, Ooplasmic Segregation, and Embryonic Axis Formation; 5.3 Contribution of Maternal Information 327 $a5.4 Postplasmic/PEM RNA's Selected References; Chapter 6: Larval Tail Muscle; 6.1 Primary (B-Line) Muscle Cells: Autonomous Specification and Gene Regulatory Networks; 6.2 Secondary (A- and -Line) Muscle Cells: Evolutionary Alteration of Gene Regulatory Networks; Selected References; Chapter 7: Endoderm; 7.1 Lineage; 7.2 Specification Mechanisms; 7.3 Differentiation Mechanisms; Selected References; Chapter 8: Epidermis; 8.1 Lineage and Specification Mechanisms; 8.2 Adhesive Organ; 8.3 Cellulose Biosynthesis; Selected References; Chapter 9: Notochord 327 $a9.1 Notochord Lineage, Cell-Fate Determination, and Morphogenesis 9.2 Specification Mechanisms and the Gene Regulatory Network; 9.3 Genes Involved in Notochord Formation; Selected References; Chapter 10: The Larval and Adult Nervous Systems; 10.1 Larval CNS; 10.2 Sensory Systems in the Larval CNS; 10.3 Peripheral Nervous System; 10.4 Remodeling of the Central Nervous System During Metamorphosis; 10.5 The Adult Nervous System; Selected References; Chapter 11: Mesenchyme; 11.1 Embryonic Lineages and Their Adult Progeny; 11.2 Molecular Cascades Involved in Mesenchymal Specification 327 $aSelected References Chapter 12: Making Blueprint of Chordate Body: Dynamic Activities of Regulatory Genes; 12.1 The Embryonic Axes Formation; 12.2 The Fate Map; 12.3 From Maternal Factors to Zygotic Activities of Regulatory Genes; 12.4 The Antagonistic Actions of FGF and Ephrin Pathways to form Germ Layers; 12.5 The Nodal and Delta 2 Signaling Relay; 12.6 The ANISEED Database as an Interface for Elucidation of Ciona Developmental Program; 12.7 Strategy of Body Plan Formation in Ascidians; 12.8 Gene Regulatory Network in Early Ciona Embryos; 12.9 Chromosomal-Level Regulation of Gene Expression 327 $a12.10 Hox Genes and Retinoic Acid 330 $aThe simplicity and lack of redundancy in their regulatory genes have made ascidians one of the most useful species in studying developmental genomics. In Developmental Genomics of Ascidians, Dr. Noriyuki Satoh explains the developmental genomics of ascidians, stresses the simplicity of Ciona developmental system, and emphasizes single-cell level analyses. This book actively accentuates the advantages of using ascidians as model organisms in an up-and-coming field of developmental genomics. 606 $aSea squirts$xAnatomy 606 $aSea squirts$xDevelopment 615 0$aSea squirts$xAnatomy. 615 0$aSea squirts$xDevelopment. 676 $a596/.2 700 $aSatoh$b Noriyuki$01720963 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910807748603321 996 $aDevelopmental genomics of ascidians$94120070 997 $aUNINA