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100   $a19860313d1996      uy         0
101 0 $aeng
135   $aur|n|---|||||
181   $ctxt
182   $cc
183   $acr
200 00$aToxicity of alternatives to chlorofluorocarbons $eHFC-134a and HCFC-123 /$fSubcommittee to Review Toxicity of Alternatives to Chlorofluorocarbons
205   $a1st ed.
210   $aWashington, D.C. $cNational Academy Press $cAvailable from [the] Committee on Human Rights$d1996
215   $a1 online resource (130 p.)
300   $aDescription based upon print version of record.
311   $a0-309-57201-0 
327   $a""Toxicity of Alternatives to Chlorofluorocarbons: HFC-134a and HCFC-123""; ""Copyright""; ""Preface""; ""Contents""; ""Executive Summary""; ""ASSESSMENT OF MODEL FOR CARDIAC SENSITIZATION""; ""EXPOSURE GUIDANCE LEVELS FOR HFC-134A""; ""EXPOSURE GUIDANCE LEVEL FOR HCFC-123""; ""1 Introduction ""; ""STATEMENT OF TASK""; ""DEFINITIONS""; ""Emergency Exposure Guidance Level""; ""Continuous Exposure Guidance Level""; ""STRUCTURE OF THE REPORT""; ""2 Evaluation of the Dog Cardiac Sensitization Test ""; ""INTRODUCTION""; ""MECHANISM OF ACTION FOR CHEMICALLY INDUCED ARRHYTHMIAS""
327   $a""PROTOCOL FOR A CARDIAC SENSITIZATION SCREENING STUDY""""CARDIAC SENSITIZATION EXPERIMENTS INVOLVING SELECTED HALOCARBONS""; ""CONCLUSION""; ""REFERENCES""; ""3 Exposure Guidance Levels for Hydrofluorocarbon-134a ""; ""INTRODUCTION""; ""BACKGROUND INFORMATION""; ""Physical and Chemical Properties""; ""Occurrence and Use""; ""TOXICOKINETICS""; ""TOXICITY INFORMATION""; ""Acute Toxicity""; ""Cardiac Sensitization""; ""Subacute Toxicity""; ""Subchronic Toxicity""; ""Developmental Toxicity""; ""Reproductive Toxicity""; ""Genotoxicity""; ""Carcinogenicity""; ""SUMMARY""
327   $a""RECOMMENDATIONS FOR EXPOSURE GUIDANCE LEVELS""""REFERENCES""; ""4 Exposure Guidance Levels for Hydrochlorofluorocarbon-123 ""; ""INTRODUCTION""; ""RECOMMENDATIONS FOR EXPOSURE GUIDANCE LEVELS""; ""REFERENCES""; ""Appendix A""; ""SUPPORTING DOCUMENTATION FOR THE EXPOSURE GUIDANCE LEVELS FOR HYDROCHLOROFLUOROCARBON-123""; ""BACKGROUND INFORMATION""; ""Physical and Chemical Properties""; ""Occurrence and Use""; ""TOXICOKINETICS""; ""TOXICITY INFORMATION""; ""Effects in Humans""; ""Effects in Animals""; ""Single-Exposure Studies""; ""Repeat-Exposure Studies""; ""EXPOSURE ASSESSMENT""
327   $a""RECOMMENDATIONS FOR EXPOSURE GUIDANCE LEVEL""""REFERENCES""; ""ATTACHMENT 1 MATERIAL SAFETY DATA SHEET""; ""ATTACHMENT 2 HALOTHANE""; ""BACKGROUND INFORMATION""; ""Physical and Chemical Properties""; ""Occurrence and Use""; ""ACUTE TOXICITY INFORMATION""; ""Acute Toxicity and CNS Depression""; ""Cardiac Sensitization""; ""Effects in Humans""; ""Malignant Hyperthermia""; ""Hepatotoxicity""; ""DISCUSSION""; ""HCFC-123 AND Halothane Comparison""; ""Acute Toxicity and CNS Depression""; ""Cardiac Sensitization""; ""Malignant Hyperthermia""; ""Hepatotoxicity""; ""REFERENCES""
327   $a""ATTACHMENT 3 SUMMARY OF TOXICITY STUDIES OF HCFC-123""""I. ANIMAL STUDIES: SINGLE EXPOSURE""; ""II. ANIMAL STUDIES: REPEAT EXPOSURE""; ""III. REFERENCES""; ""ATTACHMENT 4 SUMMARY OF ACUTE PHARMACOKINETIC STUDY OF HCFC-123 IN DOGS BY INHALATION""; ""OBJECTIVE""; ""MATERIALS AND METHODS""; ""Exposure System""; ""Blood and Tissue Sampling""; ""Analysis of Blood and Tissue Samples""; ""RESULTS""; ""DISCUSSION""
606   $aAir$xPollution
606   $aChlorofluorocarbons$xEnvironmental aspects
615  0$aAir$xPollution.
615  0$aChlorofluorocarbons$xEnvironmental aspects.
676   $a547.01046
712 02$aNational Academy of Sciences (U.S.).$bSubcommittee to Review Toxicity of Alternatives to Chlorofluorocarbons.
801  0$bMiAaPQ
801  1$bMiAaPQ
801  2$bMiAaPQ
906   $aBOOK
912   $a9910806258503321
996   $aToxicity of alternatives to chlorofluorocarbons$94091486
997   $aUNINA