LEADER 02997nam  2200601Ia 450 
001 9910806132303321
005 20230721004930.0
010   $a1-282-68987-8
010   $a9786612689871
010   $a1-4443-0071-7
010   $a1-4443-0072-5
035   $a(CKB)1000000000716009
035   $a(EBL)416502
035   $a(OCoLC)476248528
035   $a(SSID)ssj0000240841
035   $a(PQKBManifestationID)11208772
035   $a(PQKBTitleCode)TC0000240841
035   $a(PQKBWorkID)10267419
035   $a(PQKB)11157936
035   $a(MiAaPQ)EBC416502
035   $a(Au-PeEL)EBL416502
035   $a(CaPaEBR)ebr10301448
035   $a(CaONFJC)MIL268987
035   $a(EXLCZ)991000000000716009
100   $a20080709d2009      uy         0
101 0 $aeng
135   $aurcn|||||||||
181   $ctxt
182   $cc
183   $acr
200 00$aSample size tables for clinical studies /$fDavid Machin ... [et al.]
205   $a3rd ed.
210   $aChichester, UK ;$aHoboken, NJ $cWiley-Blackwell$d2009
215   $a1 online resource (264 p.)
300   $aDescription based upon print version of record.
311   $a1-4051-4650-8 
320   $aIncludes bibliographical references (p. 239-248) and indexes.
327   $aPreface; 1 Basic design considerations; 2 Distributions and confidence intervals; 3 Comparing two independent groups for binary data; 4 Comparing two independent groups for ordered categorical data; 5 Comparing two independent groups for continuous data; 6 Cluster designs, repeated measures data and more than two groups; 7 Comparing paired groups for binary, ordered categorical and continuous outcomes; 8 Comparing survival curves; 9 Equivalence; 10 Confidence intervals; 11 Post-marketing surveillance; 12 The correlation coefficient; 13 Reference intervals and receiver operating curves
327   $a14 Observer agreement studies15 Dose finding studies; 16 Phase II trials; 17 Sample size software S SS; Cumulative references; Author index; Subject index
330   $aThis book provides statisticians and researchers with the statistical tools - equations, formulae and numerical tables - to design and plan clinical studies and carry out accurate, reliable and reproducible analysis of the data so obtained. There is no way around this as incorrect procedure in clinical studies means that the researcher's paper will not be accepted by a peer-reviewed journal. Planning and analyzing clinical studies is a very complicated business and this book provides indispensable factual information.
606   $aClinical trials$xStatistical methods$vTables
606   $aMedicine
615  0$aClinical trials$xStatistical methods
615  0$aMedicine.
676   $a615.5072/4
701   $aMachin$b David$f1939-$0520765
801  0$bMiAaPQ
801  1$bMiAaPQ
801  2$bMiAaPQ
906   $aBOOK
912   $a9910806132303321
996   $aSample size tables for clinical studies$93939756
997   $aUNINA