LEADER 04534nam 22006495 450 001 9910805578603321 005 20240118083322.0 010 $a3-031-41159-5 024 7 $a10.1007/978-3-031-41159-5 035 $a(MiAaPQ)EBC31073905 035 $a(Au-PeEL)EBL31073905 035 $a(DE-He213)978-3-031-41159-5 035 $a(EXLCZ)9929977934600041 100 $a20240118d2023 u| 0 101 0 $aeng 135 $aurcnu|||||||| 181 $ctxt$2rdacontent 182 $cc$2rdamedia 183 $acr$2rdacarrier 200 10$aGenes, Environments and Interactions$b[electronic resource] $eEvolutionary and Quantitative Genetics Brought Up-to-date /$fby José M Álvarez-Castro 205 $a1st ed. 2023. 210 1$aCham :$cSpringer International Publishing :$cImprint: Springer,$d2023. 215 $a1 online resource (236 pages) 311 08$aPrint version: Álvarez-Castro, José M. Genes, Environments and Interactions Cham : Springer International Publishing AG,c2024 9783031411588 327 $aChapter 1: Discovering The Genotype -- Chapter 2: The Primeval Theory Of Ge-Netic Effects -- Chapter 3: Genetic Effects Over One Century -- Chapter 4: Hgenetic Architectures At The Individual Level -- Chapter 5: Genetic Effects In Popula-Tions Under Linkage Equilibrium -- Chapter 6: A General Theory Of Genetic Effects -- Chapter 7: Variance Decomposition, Gene Mapping And Average Excesses?Orthogonality In The Spotlight -- Chapter 8: Applied Cases Of Advanced Genetic Modelling -- Chapter 9: The Comes And Goes Of The Black Box Perspective In Quantitative Genetics -- Chapter 10: Addendum: An Acid Test For Noia. 330 $aGenetic effects are the core concepts from which quantitative genetics and the evolutionary synthesis emerged. The groundbreaking theory of genetic effects was first proposed over a century ago. This book revises that theory, both conceptually and mathematically, and brings it up-to-date. The theory here compiled is supplemented with non-previously-published developments covering the broadest spectrum of simultaneously multiallelic and multilocus architectures with autosomal and sex-linked loci Arbitrary interactions (dominance, gene-gene, gene-environment, gene-sex, and parent-of-origin interactions) are accounted for Both effects of allele substitutions from the reference of individual genotypes and in the context of populations are worked out Populations are considered regardless of any departures from equilibrium frequencies (including both departures from Hardy-Weinberg, departures from linkage equilibrium, and non-random associations between/among genes and environments) All developments are derived under the same mathematical framework, so that transformations of genetic effects between different contexts are easily allowed In brief, this book enables novel applications to current empirical paradigms (like gene-mapping and genomic prediction) while adhering to the classical conceptualization of genetic effects and variance decomposition that let quantitative genetics and the evolutionary synthesis flourish. All relevant concepts are carefully clarified and discussed from a historical perspective. The theoretical developments presented in the book are illustrated by built-in cases and applications with real data. Reassuringly, the adequacy of the theory here presented is corroborated based on the fundamentals of model development. 606 $aEvolutionary genetics 606 $aBiomathematics 606 $aEvolution (Biology) 606 $aEcological genetics 606 $aPopulation genetics 606 $aEvolutionary Genetics 606 $aMathematical and Computational Biology 606 $aEvolutionary Biology 606 $aEcological Genetics 606 $aPopulation Genetics 606 $aEvolutionary Theory 615 0$aEvolutionary genetics. 615 0$aBiomathematics. 615 0$aEvolution (Biology). 615 0$aEcological genetics. 615 0$aPopulation genetics. 615 14$aEvolutionary Genetics. 615 24$aMathematical and Computational Biology. 615 24$aEvolutionary Biology. 615 24$aEcological Genetics. 615 24$aPopulation Genetics. 615 24$aEvolutionary Theory. 676 $a572.838 700 $aÁlvarez-Castro$b José M$01589050 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910805578603321 996 $aGenes, Environments and Interactions$93883279 997 $aUNINA