LEADER 04153nam  22008055  450 
001 9910805576803321
005 20251008143605.0
010   $a9783031475672
010   $a3031475674
024 7 $a10.1007/978-3-031-47567-2
035   $a(PPN)275431304
035   $a(MiAaPQ)EBC31074350
035   $a(Au-PeEL)EBL31074350
035   $a(DE-He213)978-3-031-47567-2
035   $a(CKB)30020049300041
035   $a(OCoLC)1419062346
035   $a(EXLCZ)9930020049300041
100   $a20240119d2023      u|         0
101 0 $aeng
135   $aurcnu||||||||
181   $ctxt$2rdacontent
182   $cc$2rdamedia
183   $acr$2rdacarrier
200 10$aRespiratory Delivery of Biologics, Nucleic Acids, and Vaccines /$fedited by Jenny Lam, Philip Chi Lip Kwok
205   $a1st ed. 2023.
210  1$aCham :$cSpringer International Publishing :$cImprint: Springer,$d2023.
215   $a1 online resource (224 pages)
225 1 $aAAPS Introductions in the Pharmaceutical Sciences,$x2522-8358 ;$v8
311 08$aPrint version: Lam, Jenny Respiratory Delivery of Biologics, Nucleic Acids, and Vaccines Cham : Springer International Publishing AG,c2024 9783031475665 
327   $aChapter 1: Design strategies of dry powders for pulmonary delivery of pharmaceutical peptides -- Chapter 2. Pulmonary delivery of antibody for the treatment of respiratory diseases -- Chapter 3: Dry powder formulation of monoclonal antibodies for pulmonary delivery -- Chapter 4: Antimicrobial peptides and proteins for inhalation -- Chapter 5: Pulmonary delivery of nucleic acids -- Chapter 6: Intranasal and inhaled vaccines -- Chapter 7: Respiratory delivery of probiotics to improve lung health -- Chapter 8: Respiratory delivery of bacteriophages for the treatment of lung infections -- Chapter 9: Pharmacokinetics of inhaled medications ? what do we know about biological macromolecules?.
330   $aTherapeutic macromolecules and biologics have gained increasing importance in the last decade. Pulmonary and intranasal delivery of these therapeutic modalities, which have poor oral bioavailability, could constitute an attractive, non-invasive alternative to parenteral delivery. They can be considered for either topical use for treating diseases affecting the airways or for systemic use for treating a variety of other diseases. Therefore, this book is a readable, thoughtful, and useful guide on the latest research developments and the best options that people involved with pulmonary and intranasal route of administration and biologically active agents can bring to their practices. Furthermore, it explores the underlying scientific rationale for the strategies applied to overcome drug delivery challenges and provides insights to inspire further research in this growing area.
410  0$aAAPS Introductions in the Pharmaceutical Sciences,$x2522-8358 ;$v8
606   $aPharmaceutical chemistry
606   $aDrug delivery systems
606   $aBiologicals
606   $aBiopharmaceutics
606   $aVaccines$xBiotechnology
606   $aBiomaterials
606   $aDrugs$xDesign
606   $aPharmacology
606   $aPharmaceutics
606   $aDrug Delivery
606   $aBiologics
606   $aBiomaterials-Vaccines
606   $aStructure-Based Drug Design
606   $aPharmacology
615  0$aPharmaceutical chemistry.
615  0$aDrug delivery systems.
615  0$aBiologicals.
615  0$aBiopharmaceutics.
615  0$aVaccines$xBiotechnology.
615  0$aBiomaterials.
615  0$aDrugs$xDesign.
615  0$aPharmacology.
615 14$aPharmaceutics.
615 24$aDrug Delivery.
615 24$aBiologics.
615 24$aBiomaterials-Vaccines.
615 24$aStructure-Based Drug Design.
615 24$aPharmacology.
676   $a615.19
700   $aLam$b Jenny$01589026
701   $aKwok$b Philip Chi Lip$01589027
801  0$bMiAaPQ
801  1$bMiAaPQ
801  2$bMiAaPQ
906   $aBOOK
912   $a9910805576803321
996   $aRespiratory Delivery of Biologics, Nucleic Acids, and Vaccines$93883262
997   $aUNINA