LEADER 04266oam 2200733I 450 001 9910800073503321 005 20230721025036.0 010 $a0-429-14709-0 010 $a1-282-49554-2 010 $a9786612495540 010 $a1-4200-9455-6 024 7 $a10.1201/9781420094558 035 $a(CKB)2520000000008669 035 $a(EBL)565844 035 $a(OCoLC)664233708 035 $a(SSID)ssj0000413701 035 $a(PQKBManifestationID)11293382 035 $a(PQKBTitleCode)TC0000413701 035 $a(PQKBWorkID)10381264 035 $a(PQKB)10654732 035 $a(MiAaPQ)EBC565844 035 $a(Au-PeEL)EBL565844 035 $a(CaPaEBR)ebr10367150 035 $a(CaONFJC)MIL249554 035 $a(OCoLC)607552467 035 $a(EXLCZ)992520000000008669 100 $a20180331d2009 uy 0 101 0 $aeng 135 $aur|n|---||||| 181 $ctxt 182 $cc 183 $acr 200 10$aCell mechanics $efrom single scale-based models to multiscale modeling /$fArnaud Chauviere, Luigi Preziosi, Verdier Claude 210 1$aBoca Raton :$cChapman & Hall/CRC,$d2009. 215 $a1 online resource (484 p.) 225 1 $aChapman & Hall/CRC mathematical and computational biology series 300 $aDescription based upon print version of record. 311 $a1-4200-9454-8 311 0 $a9780367390617 320 $aIncludes bibliographical references and index. 327 $aFront cover; Part I: From Subcellular to Cellular Properties; Chapter 1. Microhenology of Living Cells at Different Time and Length Scales; Chapter 2. Actin-Based Propulsion: Intriguing Interplay between Material Properties and Growth Processes; Chapter 3. Cancer: Cell Motility and Tumor Suppessor Genes; Part II: Single Cell Migration Modeling; Chapter 4. Coupling of Cytoplasm and Adhesion Dynamics Determines Cell Polarization and Locomotion; Chapter 5. How Do Cells Move? Mathematical Modeling of Cytoskeleton Dynamic and Cell Migration 327 $aChapter 6. Computational Framework Integrating Cytoskeletal and Adhesion Dynamics for Modeling Cell MotilityPart III: Mechanical Effects of Environment on Cell Behavior; Chapter 7. History Dependence of Mocrobead Adhesion under Varying Shear Rate; Chapter 8. Understanding Adhesion Sites as Mechanosensitive Cellular Elements; Chapter 9. Cancer Cell Migration on 2-D Deformable Substrates; Chapter 10. Single-Cell Imaging of Calcium in Response to Mechanical Stimulation; Part IV: From Cellular to Multicellular Models 327 $aChapter 11. Mathematical Framework to Model Migration of Cell Population in Extracellular MatrixChapter 12. Mathematical Modeling of Cell Adhesion and Its Applications to Developmental Biology and Cancer Invasion; Chapter 13. Bridging Cell and Tissue Behavior in Embryo Development; Chapter 14. Modeling Steps from Benign Tumor to Invasion Cancer: Examples of Intrinsically Multiscale Problems; Chapter 15. Delaunay Object Dynamics for Tissues Involving Highly Motile Cells; Index; Back cover 330 $aUbiquitous and fundamental in cell mechanics, multiscale problems can arise in the growth of tumors, embryogenesis, tissue engineering, and more. This book discusses the tool of microrheology for investigating cell mechanical properties, and multiphysics and multiscale approaches for studying intracellular mechanisms in cell motility. 410 0$aChapman and Hall/CRC mathematical & computational biology series. 606 $aCells$xMechanical properties$xMathematical models 606 $aCells$xMechanical properties$xComputer simulation 606 $aTumors$xGrowth$xMathematical models 606 $aTumors$xGrowth$xComputer simulation 615 0$aCells$xMechanical properties$xMathematical models. 615 0$aCells$xMechanical properties$xComputer simulation. 615 0$aTumors$xGrowth$xMathematical models. 615 0$aTumors$xGrowth$xComputer simulation. 676 $a571.6 700 $aChauviere$b Arnaud.$01586847 701 $aPreziosi$b Luigi$032041 701 $aVerdier$b Claude$01586848 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910800073503321 996 $aCell mechanics$93873953 997 $aUNINA