LEADER 04508nam 22007695 450 001 9910799226603321 005 20240304211915.0 010 $a3-031-45903-2 024 7 $a10.1007/978-3-031-45903-0 035 $a(MiAaPQ)EBC31054872 035 $a(Au-PeEL)EBL31054872 035 $a(DE-He213)978-3-031-45903-0 035 $a(EXLCZ)9929516173300041 100 $a20240104d2023 u| 0 101 0 $aeng 135 $aurcnu|||||||| 181 $ctxt$2rdacontent 182 $cc$2rdamedia 183 $acr$2rdacarrier 200 10$aPharmacogenomics in Clinical Practice$b[electronic resource] /$fedited by Dragan Primorac, Wolfgang Höppner, Lidija Bach-Rojecky 205 $a1st ed. 2023. 210 1$aCham :$cSpringer International Publishing :$cImprint: Springer,$d2023. 215 $a1 online resource (484 pages) 311 08$aPrint version: Primorac, Dragan Pharmacogenomics in Clinical Practice Cham : Springer International Publishing AG,c2024 9783031459023 327 $aContents -- Contributors -- Introduction -- Principles of Pharmacogenomics -- Principles of xenobiotic metabolism (Biotransformation) -- Pharmacogenomics of drug-metabolizing enzymes -- Role of membrane transporters in pharmacogenomics -- Role of drug receptors in pharmacogenomics -- Role of drug targets and other proteins important in pharmacogenomics -- Pharmacogenomics algorithms in clinical practice -- Pharmacogenomics in pain treatment -- Pharmacogenomics in psychiatric diseases -- Pharmacogenomics in anesthesia -- Pharmacogenomics in cardiovascular diseases -- Pharmacogenomics in gastroenterology -- Pharmacogenomics in cancer therapeutics -- Pharmacogenomics on immunosuppressive drugs in solid organ transplantation -- Pharmacogenomics and big data -- Public health issues in Pharmacogenomics -- Ethical Issues in Pharmacogenomics -- Economic evaluation of Pharmacogenomic Testing -- Role of public data bases for pharmacogenomics -- Pharmacogenomics education at University -- Pharmacogenomics in drug research development -- Future perspectives -- Index. 330 $aThis book provides a practically applicable guide to the applications of pharmogenomics across medicine. Background information is provided on the mechanisms associated with membrane transporters, drug-metabolizing enzymes and their importance in pharmagenomics. Detailed guidance is subsequently presented on how to apply these techniques in disciplines including cardiology, gastroenterology, oncology, transplantation surgery, infectious diseases, anesthesia and analgesia, neurology, psychiatry, primary care, and public health. Clear easy-to-follow instructions are given on how to use big data technologies and public health databases in day-to-day clinical practice. Pharmacogenomics in Clinical Practice concisely covers how pharmacogenomic technologies and techniques can be applied in daily medical practice. It is therefore an ideal up-to-date resource for any medical practitioner, trainee or researcher across all medical disciplines who want to better understand how to use these techniques. 606 $aMedicine 606 $aPharmacology 606 $aMedical genetics 606 $aPractice of medicine 606 $aHospitals$xAdministration 606 $aPharmacovigilance 606 $aPharmacogenetics 606 $aGenetics, Medical 606 $aClinical Medicine 606 $aPharmacovigilance 606 $aClinical Medicine 606 $aPharmacology 606 $aMedical Genetics 606 $aPractice and Hospital Management 606 $aDrug Safety and Pharmacovigilance 615 0$aMedicine. 615 0$aPharmacology. 615 0$aMedical genetics. 615 0$aPractice of medicine. 615 0$aHospitals$xAdministration. 615 0$aPharmacovigilance. 615 2$aPharmacogenetics. 615 2$aGenetics, Medical 615 2$aClinical Medicine 615 2$aPharmacovigilance. 615 14$aClinical Medicine. 615 24$aPharmacology. 615 24$aMedical Genetics. 615 24$aPractice and Hospital Management. 615 24$aDrug Safety and Pharmacovigilance. 676 $a610 700 $aPrimorac$b Dragan$01586109 701 $aHöppner$b Wolfgang$01586110 701 $aBach-Rojecky$b Lidija$01586111 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910799226603321 996 $aPharmacogenomics in Clinical Practice$93872381 997 $aUNINA