LEADER 05432nam 2200649 450 001 9910798073203321 005 20200520144314.0 010 $a0-12-801600-0 035 $a(CKB)3710000000459595 035 $a(EBL)2131145 035 $a(SSID)ssj0001625594 035 $a(PQKBManifestationID)16362468 035 $a(PQKBTitleCode)TC0001625594 035 $a(PQKBWorkID)14930939 035 $a(PQKB)11132060 035 $a(MiAaPQ)EBC2131145 035 $a(Au-PeEL)EBL2131145 035 $a(CaPaEBR)ebr11086768 035 $a(CaONFJC)MIL822629 035 $a(OCoLC)918624022 035 $a(PPN)193663767 035 $a(EXLCZ)993710000000459595 100 $a20150820h20152015 uy 0 101 0 $aeng 135 $aur|n|---||||| 181 $ctxt 182 $cc 183 $acr 200 00$aTendon regeneration $eunderstanding tissue physiology and development to engineer functional substitutes /$fedited by Manuela E. Gomes, Rui L. Reis, Marcia T. Rodrigues 210 1$aAmsterdam, [Netherlands] :$cAcademic Press,$d2015. 210 4$dİ2015 215 $a1 online resource (471 p.) 300 $aDescription based upon print version of record. 311 $a0-12-801590-X 320 $aIncludes bibliographical references at the end of each chapters and index. 327 $aFront Cover; TENDON REGENERATION; Copyright; CONTENTS; CONTRIBUTORS; PREFACE; SECTION 1 - Biology and Physiologyof Tendons; Chapter 1 - Tendon Physiology and Mechanical Behavior: Structure-Function Relationships; 1. TENDON STRUCTURE AND COMPOSITION; 2. TENDON MECHANICS; 3. MULTISCALE MECHANICS AND STRUCTURE-FUNCTION CHARACTERIZATION; 4. MECHANICAL AND COMPOSITIONAL VARIATIONS IN TENDONS WITH DIFFERENT FUNCTIONS; LIST OF ABBREVIATIONS; GLOSSARY; REFERENCES; Chapter 2 - Tendon Resident Cells-Functions and Features in Section I-Developmental Biology and Physiology of Tendons; 1. INTRODUCTION 327 $a2. TENDON CELLS-ORIGIN AND SPECIFICATION3. TENDON CELLS-ECM SYNTHESIS, ASSEMBLY, AND TISSUE MATURATION; 4. CELL-ECM INTERACTIONS; 5. MECHANOREGULATION OF TENDON CELLS; 6. CONCLUSION; LIST OF ABBREVIATIONS; GLOSSARY; REFERENCES; Chapter 3 - Mechanobiology of Embryonic and Adult Tendons; 1. INTRODUCTION; 2. EMBRYONIC TENDON; 3. POSTNATAL TENDON; 4. MECHANICAL CUES EXPERIENCED BY EMBRYONIC, POSTNATAL, AND ADULT TENDONS; 5. STUDIES IN THE EMBRYO SUGGEST MECHANICAL FACTORS INFLUENCE EMBRYONIC TENDON DEVELOPMENT; 6. IN VITRO STUDIES SUGGEST MECHANICAL FACTORS INFLUENCE EMBRYONIC TENDON DEVELOPMENT 327 $a7. EXERCISE STUDIES EXAMINE THE INFLUENCE OF MECHANICS IN ADULT TENDON8. IN VITRO STUDIES SUGGEST MECHANICAL FACTORS INFLUENCE ADULT TENDON HOMEOSTASIS; 9. POTENTIAL MECHANISMS OF TENDON CELL MECHANOTRANSDUCTION; 10. CONCLUSIONS; LIST OF ABBREVIATIONS; REFERENCES; SECTION 2 - Pathologies and Repairof Tendons; Chapter 4 - Tendinopathy I: Understanding Epidemiology, Pathology, Healing, and Treatment; 1. INTRODUCTION; 2. ANATOMICAL DIAGNOSIS; 3. PATHOLOGY; 4. EPIDEMIOLOGY; 5. PATHOPHYSIOLOGY; 6. HEALING AND REPAIR; 7. NONSURGICAL TREATMENT; 8. SURGICAL TREATMENT; 9. CONCLUSION 327 $aLIST OF ABBREVIATIONSGLOSSARY; REFERENCES; Chapter 5 - Tendinopathy II: Etiology, Pathology, and Healing of Tendon Injury and Disease; 1. EPIDEMIOLOGY; 2. DEFINITIONS; 3. TENDINOPATHY ETIOLOGY; 4. PATHOLOGY; 5. SUMMARY AND CONCLUSIONS; LIST OF ABBREVIATIONS; GLOSSARY; REFERENCES; SECTION 3 - Tendon Regenerative Medicine Approaches; Chapter 6 - Cell-Based Approaches for Tendon Regeneration; 1. INTRODUCTION; 2. TENDON ENDOGENOUS REGENERATION; 3. ISOLATION PROCEDURES OF TENDON RESIDENT CELLS; 4. ALTERNATIVE STEM CELLS SOURCES FOR CELL-BASED TENDON TISSUE ENGINEERING 327 $a5. MOVING CELL THERAPIES INTO THE CLINICS6. CONCLUSION; LIST OF ABBREVIATIONS; GLOSSARY; REFERENCES; Chapter 7 - The Role of Growth Factors in Tendon Stimulation; 1. INTRODUCTION; 2. GROWTH FACTORS; 3. PLATELET-RICH PLASMA; 4. CONCLUSIONS; LIST OF ABBREVIATIONS; REFERENCES; SECTION 4 - Scaffolds-Based Approaches; Chapter 8 - Engineering Anisotropic 2D and 3D Structures for Tendon Repair and Regeneration; 1. INTRODUCTION; 2. ANISOTROPIC SPONGES; 3. ANISOTROPIC SELF-ASSEMBLED FIBERS; 4. ANISOTROPIC ELECTROSPUN FIBERS; 5. ANISOTROPIC IMPRINTED SUBSTRATES; 6. CONCLUSIVE REMARKS 327 $aLIST OF ABBREVIATIONS 330 $a Tendon Regeneration: Understanding Tissue Physiology and Development to Engineer Functional Substitutes is the first book to highlight the multi-disciplinary nature of this specialized field and the importance of collaboration between medical and engineering laboratories in the development of tissue-oriented products for tissue engineering and regenerative medicine (TERM) strategies. Beginning with a foundation in developmental biology, the book explores physiology, pathology, and surgical reconstruction, providing guidance on biological approaches that enhances tendon regeneration practi 606 $aTendons 606 $aTendons$xWounds and injuries$xHealing 615 0$aTendons. 615 0$aTendons$xWounds and injuries$xHealing. 676 $a636.10897474044 702 $aGomes$b Manuela E. 702 $aReis$b Rui L. 702 $aRodrigues$b Marcia T. 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910798073203321 996 $aTendon regeneration$93781431 997 $aUNINA