LEADER 02198nam 2200565 450 001 9910797619103321 005 20200520144314.0 010 $a0-7391-9423-2 035 $a(CKB)3710000000491355 035 $a(EBL)4085768 035 $a(SSID)ssj0001562972 035 $a(PQKBManifestationID)16213148 035 $a(PQKBTitleCode)TC0001562972 035 $a(PQKBWorkID)14016419 035 $a(PQKB)11763822 035 $a(MiAaPQ)EBC4085768 035 $a(Au-PeEL)EBL4085768 035 $a(CaPaEBR)ebr11120803 035 $a(CaONFJC)MIL841000 035 $a(OCoLC)934998378 035 $a(EXLCZ)993710000000491355 100 $a20151208h20162016 uy 0 101 0 $aeng 135 $aur|n|---||||| 181 $ctxt 182 $cc 183 $acr 200 10$aIshimure Michiko's writing in ecocritical perspective $ebetween sea and sky /$fBruce Allen and Yuki Masami ; contributors, Ikezawa Natsuki [and seven others] 210 1$aLanham, Maryland :$cLexington Books,$d2016. 210 4$dİ2016 215 $a1 online resource (215 p.) 225 1 $aEcocritical Theory and Practice 300 $aDescription based upon print version of record. 311 $a0-7391-9422-4 320 $aIncludes bibliographical references at the end of each chapters and index. 330 $aThis collection of ecocritical essays focuses on the work of Ishimure Michiko, Japan's foremost writer on the environment and culture. It discusses Ishimure's writing in the context of the latest issues in ecocritical theory, with particular reference to environmental problems in Minamata and Fukushima, and argues for an expanded, more-than-Western understanding of literature, theory, and environmental responsibility. 410 0$aEcocritical theory and practice. 606 $aEcocriticism 615 0$aEcocriticism. 676 $a895.63/5 700 $aAllen$b Bruce$f1949-$01499736 702 $aMasami$b Yuki$f1969- 702 $aNatsuki$b Ikezawa 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910797619103321 996 $aIshimure Michiko's writing in ecocritical perspective$93726051 997 $aUNINA LEADER 03828nam 2200625Ia 450 001 9910830423703321 005 20170815111618.0 010 $a1-280-72115-4 010 $a9786610721153 010 $a0-470-02933-1 010 $a0-470-02932-3 035 $a(CKB)1000000000357355 035 $a(EBL)281583 035 $a(SSID)ssj0000169749 035 $a(PQKBManifestationID)11161703 035 $a(PQKBTitleCode)TC0000169749 035 $a(PQKBWorkID)10223443 035 $a(PQKB)10226153 035 $a(MiAaPQ)EBC281583 035 $a(OCoLC)85821076 035 $a(EXLCZ)991000000000357355 100 $a20050211d2006 uy 1 101 0 $aeng 135 $aur|n|---||||| 181 $ctxt 182 $cc 183 $acr 200 00$aHeart failure$b[electronic resource] $emolecules, mechanisms and therapeutic targets 210 $aChichester $cJohn Wiley$d2006 215 $a1 online resource (303 p.) 225 1 $aNovartis Foundation symposium ;$v274 300 $aDescription based upon print version of record. 311 $a0-470-01597-7 320 $aIncludes bibliographical references and indexes. 327 $aCover; Contents; Introduction; Control of cardiac hypertrophy and heart failure by histone acetylation/deacetylation; DISCUSSION; A novel mechanism of mechanical stress-induced hypertrophy; DISCUSSION; Controlling cardiomyocyte survival; DISCUSSION; Mechanisms of angiotensin II-dependent progression to heart failure; DISCUSSION; Alterations in myocardial gene expression as a basis for cardiomyopathies and heart failure; DISCUSSION; Role of the insulin-like growth factor 1 (IGF1)/phosphoinositide-3-kinase (PI3K) pathway mediating physiological cardiac hypertrophy; DISCUSSION 327 $aRole of Akt in cardiac growth and metabolismDISCUSSION; Novel therapy for heart failure and exercise-induced ventricular tachycardia based on 'fixing' the leak in ryanodine receptors; DISCUSSION; GENERAL DISCUSSION I; Phospholamban as a therapeutic modality in heart failure; DISCUSSION; Sarcomere protein gene mutations and inherited heart disease: a b cardiac myosin heavy chain mutation causing endocardial fibroelastosis and heart failure; DISCUSSION; The cardiomyocyte cell cycle; DISCUSSION; Restoration of cardiac function with progenitor cells; DISCUSSION 327 $aSignalling pathways in cardiac regenerationDISCUSSION; Beyond small molecule drugs for heart failure: prospects for gene therapy; DISCUSSION; Dual roles of telomerase in cardiac protection and repair; DISCUSSION; Final general discussion; Closing remarks: historical perspective; Contributor index; Subject index 330 $aHeart failure is the main cause of death and disability in the industrialized world. There is a major need for novel therapeutics for prevention and reversal of cardiac pathology associated with heart failure and cardiac enlargement. Over recent years, dramatic progress has been made in unravelling the cellular circuitry involved in cardiac failure, as well as in normal cardiac growth, development and apoptosis. This work has revealed new and unexpected therapeutic targets in the heart. In addition, advances in understanding the role of stem cells in cardiac physiology have suggested strategie 410 0$aNovartis Foundation symposium ;$v274. 606 $aHeart failure 606 $aHeart failure$xTreatment$xPathophysiology 606 $aHeart$xAdaptation 615 0$aHeart failure. 615 0$aHeart failure$xTreatment$xPathophysiology. 615 0$aHeart$xAdaptation. 676 $a616.129 676 $a616.12906 712 02$aNovartis Foundation. 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910830423703321 996 $aHeart failure$9774825 997 $aUNINA