LEADER 05654nam 2200697 450 001 9910797258803321 005 20200520144314.0 010 $a0-12-801317-6 035 $a(CKB)3710000000416572 035 $a(EBL)2056909 035 $a(OCoLC)910447567 035 $a(SSID)ssj0001568587 035 $a(PQKBManifestationID)16218617 035 $a(PQKBTitleCode)TC0001568587 035 $a(PQKBWorkID)14836193 035 $a(PQKB)10211352 035 $a(MiAaPQ)EBC2056909 035 $a(Au-PeEL)EBL2056909 035 $a(CaPaEBR)ebr11058681 035 $a(CaONFJC)MIL788492 035 $a(OCoLC)910159094 035 $a(PPN)19678588X 035 $a(EXLCZ)993710000000416572 100 $a20150721h20152015 uy| 0 101 0 $aeng 135 $aur|n|---||||| 181 $ctxt 182 $cc 183 $acr 200 00$aNanotechnology in diagnosis, treatment and prophylaxis of infectious diseases /$fedited by Mahendra Rai, Biotechnology Department, SGB Amravati University, Amravati, Maharashtra, India, Kateryna Kon, Department of Microbiology, Virology and Immunology, Kharkiv National Medical University, Kharkiv, Ukraine 210 1$aAmsterdam :$cElsevier,$d[2015] 210 4$dİ2015 215 $a1 online resource (361 p.) 300 $aDescription based upon print version of record. 311 $a0-12-801471-7 320 $aIncludes bibliographical references and index. 327 $a""Front Cover""; ""Nanotechnology in Diagnosis, Treatment and Prophylaxis of Infectious Diseases""; ""Copyright Page""; ""Contents""; ""List of Contributors""; ""Preface""; ""1 Gold and Silver Nanoparticles for Diagnostics of Infection""; ""1.1 Nanotechnology and Infection""; ""1.2 Gold and Silver NPs for Molecular Diagnostics""; ""1.2.1 Biomarkers""; ""1.3 Nanodiagnostics for Nucleic Acids""; ""1.3.1 Homogeneous Colorimetric Assays""; ""1.3.1.1 Unmodified NPs""; ""1.3.1.2 Cross-Linking""; ""1.3.1.3 Noncross-Linking""; ""1.3.2 Heterogeneous Detection""; ""1.3.2.1 Microarrays"" 327 $a""1.3.2.2 Lateral Flow Assays""""1.3.3 Electrochemical Assays""; ""1.3.4 Fluorescence Assays""; ""1.3.5 Raman and SERS""; ""1.3.6 Other""; ""1.4 Aptamers and Antibodies""; ""1.4.1 Colorimetric""; ""1.4.2 Electrochemical""; ""1.4.3 Lateral Flow Assays""; ""1.5 iPCR and Other Methods""; ""1.6 Conclusion""; ""References""; ""2 Antimicrobial Models in Nanotechnology: From the Selection to Application in the Control and Treatment of Infectious Diseases""; ""2.1 Introduction""; ""2.2 Antimicrobial Susceptibility Testing Methods of NMs""; ""2.2.1 Broth Dilution Test"" 327 $a""2.2.2 Spectrophotometric Measurement""""2.2.3 Cell Counting""; ""2.2.4 Colorimetric and Fluorescent Assays""; ""2.2.5 In Vitro Infection Animal Model""; ""2.2.6 Biocidal Testing""; ""2.2.7 Antibiofilm Activity""; ""2.2.8 Quorum-Sensing Inhibitors""; ""2.2.9 Microbial Membrane Lysis""; ""2.2.10 Microbial Oxidative Stress""; ""2.2.11 Antipersister and Antidormancy Bacterial Cells""; ""2.2.12 Microbial Fitness""; ""2.3 Nanotoxicology""; ""2.3.1 Nano-Genotoxicology""; ""2.3.2 Cytotoxicity""; ""2.3.3 Immunotoxicity""; ""2.3.4 In Vitro Skin Irritation"" 327 $a""2.3.5 Caenorhabditis elegans Toxicity Model""""2.3.6 Nanotoxicity in Embryonic and Adult Zebrafish""; ""2.3.7 Bioluminescence-Based Nanotoxicity Test""; ""2.4 In Vitro Pharmacokinetics/Pharmacodynamic Models""; ""2.4.1 Particokinetics""; ""2.4.2 Caco-2 Permeability""; ""2.4.3 Hollow Fiber System""; ""2.5 Conclusions""; ""References""; ""3 Silver Nanoparticles for the Control of Vector-Borne Infections""; ""3.1 Introduction""; ""3.2 Louse-Borne Infections and Activity of AgNPs Against Lice""; ""3.3 Mosquito-Borne Infections and Activity of AgNPs Against Mosquitoes"" 327 $a""3.4 Tick-Borne Infections and Activity of AgNPs Against Ticks""""3.5 Flies, Their Role in Transmission and Spread of Infections, and Activity of AgNPs Against Flies""; ""3.6 Conclusions and Future Prospects""; ""References""; ""4 Magnetite Nanostructures: Trends in Anti-Infectious Therapy""; ""4.1 Introduction""; ""4.2 Nanoparticles with Biomedical Applications""; ""4.2.1 Design of Tailored Magnetic Nanoparticles with Applications in Microbiology""; ""4.2.2 Magnetite Nanoparticles Used to Control Microorganisms Attachment and Biofilm Formation"" 327 $a""4.2.3 The Biocompatibility of Magnetite Nanoparticles"" 330 $a Nanotechnology in Diagnosis, Treatment and Prophylaxis of Infectious Diseases delivers comprehensive coverage of the application of nanotechnology to pressing problems in infectious disease. This text equips readers with cutting-edge knowledge of promising developments and future prospects in nanotechnology, paying special attention to microbes that are now resistant to conventional antibiotics, a concerning problem in modern medicine. Readers will find a thorough discussion of this new approach to infectious disease treatment, including the reasons nanotechnology presents a promising 606 $aNanotechnology$xHealth aspects 606 $aMedical technology 606 $aNanomedicine 606 $aCommunicable diseases 615 0$aNanotechnology$xHealth aspects. 615 0$aMedical technology. 615 0$aNanomedicine. 615 0$aCommunicable diseases. 676 $a612.8252 702 $aRai$b Mahendra 702 $aKon$b Kateryna 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910797258803321 996 $aNanotechnology in diagnosis, treatment and prophylaxis of infectious diseases$93783494 997 $aUNINA