LEADER 04099oam 2200745I 450 001 9910796929503321 005 20190503073424.0 010 $a0-262-32720-1 010 $a0-262-53378-2 010 $a0-262-32719-8 035 $a(CKB)3710000000370530 035 $a(SSID)ssj0001440278 035 $a(PQKBManifestationID)11823490 035 $a(PQKBTitleCode)TC0001440278 035 $a(PQKBWorkID)11384796 035 $a(PQKB)10695834 035 $a(StDuBDS)EDZ0001195976 035 $a(MiAaPQ)EBC3339945 035 $a(OCoLC)904398377 035 $a(MdBmJHUP)muse45848 035 $a(OCoLC)904398377$z(OCoLC)905918557$z(OCoLC)964595708$z(OCoLC)1055335538$z(OCoLC)1066690011$z(OCoLC)1081283454 035 $a(OCoLC-P)904398377 035 $a(MaCbMITP)10265 035 $a(Au-PeEL)EBL3339945 035 $a(CaPaEBR)ebr11028415 035 $a(CaONFJC)MIL749615 035 $a(EXLCZ)993710000000370530 100 $a20150305d2015 uy 0 101 0 $aeng 135 $aur||||||||||| 181 $ctxt 182 $cc 183 $acr 200 14$aThe genealogy of a gene $epatents, HIV/AIDS, and race /$fMyles W. Jackson 210 1$aCambridge, Massachusetts :$cThe MIT Press,$d[2015] 215 $a1 online resource (xii, 336 pages) $cillustrations (black and white) 225 1 $aTransformations: studies in the history of science and technology 300 $aBibliographic Level Mode of Issuance: Monograph 311 $a1-336-18329-2 311 $a0-262-02866-2 320 $aIncludes bibliographical references and index. 327 $aThe CCR5 story -- The CCR5 patent(s) -- Gene patenting and the product-of-nature doctrine -- CCR5 and intellectual property law -- The European response to the CCR5 patent -- CCR5 and HIV/AIDS diagnostics and therapeutics -- Race, place, and pathogens -- Race, difference, and genes -- Epilogue: the end of an error? 330 $aIn The Genealogy of a Gene, Myles Jackson uses the story of the CCR5 gene to investigate the interrelationships among science, technology, and society. Mapping the varied "genealogy" of CCR5 -- intellectual property, natural selection, Big and Small Pharma, human diversity studies, personalized medicine, ancestry studies, and race and genomics -- Jackson links a myriad of diverse topics. The history of CCR5 from the 1990s to the present offers a vivid illustration of how intellectual property law has changed the conduct and content of scientific knowledge, and the social, political, and ethical implications of such a transformation. The CCR5 gene began as a small sequence of DNA, became a patented product of a corporation, and then, when it was found to be an AIDS virus co-receptor with a key role in the immune system, it became part of the biomedical research world -- and a potential moneymaker for the pharmaceutical industry. When it was further discovered that a mutation of the gene found in certain populations conferred near-immunity to the AIDS virus, questions about race and genetics arose. Jackson describes these developments in the context of larger issues, including the rise of "biocapitalism," the patentability of products of nature, the difference between U.S. and European patenting approaches, and the relevance of race and ethnicity to medical research. 410 0$aTransformations (M.I.T. Press). 606 $aGenes 606 $aGenes$xPatents 606 $aGenetic genealogy 606 $aHIV (Viruses) 606 $aHuman population genetics 610 $aSCIENCE, TECHNOLOGY & SOCIETY/History of Science 610 $aBIOMEDICAL SCIENCES/General 610 $aSOCIAL SCIENCES/Political Science/Public Policy & Law 615 0$aGenes. 615 0$aGenes$xPatents. 615 0$aGenetic genealogy. 615 0$aHIV (Viruses) 615 0$aHuman population genetics. 676 $a362.19697/920072 700 $aJackson$b Myles W.$0991898 801 0$bOCoLC-P 801 1$bOCoLC-P 906 $aBOOK 912 $a9910796929503321 996 $aThe genealogy of a gene$93777365 997 $aUNINA