LEADER 04014nam 2200709 450 001 9910794024803321 005 20211105163726.0 010 $a1-5261-4510-3 010 $a1-5261-5555-9 010 $a1-5261-4509-X 024 7 $a10.7765/9781526145093 035 $a(CKB)4100000011243117 035 $a(OCoLC)1155603086 035 $a(MdBmJHUP)muse82631 035 $a(MiAaPQ)EBC6198946 035 $a(StDuBDS)EDZ0002390410 035 $a(DE-B1597)660013 035 $a(DE-B1597)9781526145093 035 $a(EXLCZ)994100000011243117 100 $a20200320e20212020 fy| 0 101 0 $aeng 135 $aur|||||||nn|n 181 $ctxt$2rdacontent 182 $cc$2rdamedia 183 $acr$2rdacarrier 200 04$aThe road to Brexit $ea cultural perspective on British attitudes to Europe /$fIna Habermann 210 1$aManchester :$cManchester University Press,$d2021. 215 $a1 online resource (xv, 256 pages) $cillustrations 225 1 $aManchester scholarship online 300 $aPreviously issued in print: 2020. 311 $a1-5261-4508-1 320 $aIncludes bibliographical references and index. 327 $aIntroduction : understanding the past, facing the future / Ina Habermann -- Not with a bang but a whimper : Brexit in historical perspective / Robert Holland -- 'This is something which we know, in our bones, we cannot do' : hopes and fears for a united Europe in Britain after the Second World War / Lara Feigel and Alisa Miller -- EU enlargement and the freedom of movement : imagined communities in the Conservative Party's discourse on Europe (1997-2016) / Marlene Herrschaft- Iden -- The discursive role of Europe in a disunited kingdom / Klaus Stolz -- 'Extr'ord'nary people, the Germans' : Germans as aliens in post-war British popular culture / Judith Vonberg -- 'I don't want to be a European' : the European other in British cultural discourse / Menno Spiering -- The dystopian nightmare of a European superstate : British fiction and the EU / Lisa Bischoff -- A case for a green Brexit? Paul Kingsnorth, John Berger and the pros and cons of a sense of place / Christian Schmitt- Kilb -- Brexit and the Tudor turn : Philippa Gregory's narratives of national grievance / Siobhan O'Connor -- Guards of Brexit? Revisiting the cultural significance of the white cliffs of Dover / Melanie Ku?ng -- From Iron Curtains to Iron Cliffs : British travel writing between East and West / Blanka Blagojevic -- Fifty years of unbelonging : a Gibraltarian writer's personal testimonial on the road to Brexit / M.G. Sanchez. 330 8 $aThis collection of essays explores British attitudes to Continental Europe that explain the Brexit decision. Addressing British-European entanglements and the impact of British Euroscepticism, the book argues that Britain is in denial about the strength of its ties to Europe, and that it needs to face Europe if it is to face the future. 410 0$aManchester scholarship online. 606 $aBritish$xAttitudes 606 $aPublic opinion$zGreat Britain 606 $aLITERARY CRITICISM / European / English, Irish, Scottish, Welsh$2bisacsh 607 $aGreat Britain$xForeign relations$zEuropean Union countries 607 $aEuropean Union countries$xForeign relations$zGreat Britain 610 $aBrexLit. 610 $aBrexit. 610 $aBritish exceptionalism. 610 $aBritishness. 610 $aCultural identity. 610 $aCultural memory. 610 $aEnglish literature. 610 $aEnglishness. 610 $aEuropean Union. 610 $aEuroscepticism. 610 $aIsland myth. 615 0$aBritish$xAttitudes. 615 0$aPublic opinion 615 7$aLITERARY CRITICISM / European / English, Irish, Scottish, Welsh. 676 $a327.4104 702 $aHabermann$b Ina$f1965- 801 0$bStDuBDS 801 1$bStDuBDS 906 $aBOOK 912 $a9910794024803321 996 $aThe road to Brexit$93769437 997 $aUNINA LEADER 03938nam 22009613a 450 001 9910673903503321 005 20250203235434.0 010 $a9783039212460 010 $a303921246X 024 8 $a10.3390/books978-3-03921-246-0 035 $a(CKB)4920000000094866 035 $a(oapen)https://directory.doabooks.org/handle/20.500.12854/52942 035 $a(ScCtBLL)44eb40f0-a57c-4bb7-9e90-967a9910c1af 035 $a(OCoLC)1126097025 035 $a(oapen)doab52942 035 $a(EXLCZ)994920000000094866 100 $a20250203i20192019 uu 101 0 $aeng 135 $aurmn|---annan 181 $ctxt$2rdacontent 182 $cc$2rdamedia 183 $acr$2rdacarrier 200 00$aMechanisms of Adiponectin Action$fTania Fiaschi 210 $cMDPI - Multidisciplinary Digital Publishing Institute$d2019 210 1$aBasel, Switzerland :$cMDPI,$d2019. 215 $a1 electronic resource (222 p.) 311 08$a9783039212453 311 08$a3039212451 330 $aThe adipokine adiponectin is very concentrated in plasma, and decreased levels of adiponectin are associated with pathological conditions such as obesity, diabetes, cardiovascular diseases, and metabolic syndrome. When produced in its full-length form, adiponectin self-associates to generate multimeric complexes. The full-length form of adiponectin can be cleaved by the globular form of elastase that is produced locally, and the resulting biological effects are exerted in a paracrine or autocrine manner. The different forms of adiponectin bind to specific receptors consisting of two G-protein-independent, seven-transmembrane-spanning receptors, called AdipoR1 and AdipoR2, while T-cadherin has been identified as a potential receptor for high molecular weight complexes of adiponectin. Adiponectin exerts a key role in cellular metabolism, regulating glucose levels as well as fatty acid breakdown. However, its biological effects are heterogeneous, involving multiple target tissues. The Special Issue "Mechanisms of Adiponectin Action" highlights the pleiotropic role of this hormone through 3 research articles and 7 reviews. 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