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101 0 $aeng
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200 00$aTextbook of clinical trials in oncology $ea statistical perspective /$fedited by Susan Halabi, Stefan Michiels
210  1$aBoca Raton, Florida :$cCRC Press,$d[2019]
215   $a1 online resource (645 pages)
300   $a"A Chapman & Hall Book"--Title page.
311   $a1-138-08377-1 
320   $aIncludes bibliographical references and index.
330   $aThere is an increasing need for educational resources for statisticians and investigators. Reflecting this, the goal of this book is to provide readers with a sound foundation in the statistical design, conduct, and analysis of clinical trials. Furthermore, it is intended as a guide for statisticians and investigators with minimal clinical trial experience who are interested in pursuing a career in this area. The advancement in genetic and molecular technologies have revolutionized drug development. In recent years, clinical trials have become increasingly sophisticated as they incorporate genomic studies, and efficient designs (such as basket and umbrella trials) have permeated the field. This book offers the requisite background and expert guidance for the innovative statistical design and analysis of clinical trials in oncology. Key Features: Cutting-edge topics with appropriate technical background Built around case studies which give the work a "hands-on" approach Real examples of flaws in previously reported clinical trials and how to avoid them Access to statistical code on the book's website Chapters written by internationally recognized statisticians from academia and pharmaceutical companies Carefully edited to ensure consistency in style, level, and approach Topics covered include innovating phase I and II designs, trials in immune-oncology and rare diseases, among many others
606   $aCancer$xResearch$xStatistical methods
606   $aClinical trials$xStatistical methods
615  0$aCancer$xResearch$xStatistical methods.
615  0$aClinical trials$xStatistical methods.
676   $a616.99400727
702   $aHalabi$b Susan
702   $aMichiels$b Stefan
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801  1$bOCoLC-P
906   $aBOOK
912   $a9910793554503321
996   $aTextbook of clinical trials in oncology$93834417
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