LEADER 03431nam 2200505 450 001 9910792730803321 005 20230809223346.0 010 $a3-11-049355-1 024 7 $a10.1515/9783110493764 035 $a(CKB)3710000001123496 035 $a(MiAaPQ)EBC4830573 035 $a(DE-B1597)469989 035 $a(OCoLC)984688420 035 $a(DE-B1597)9783110493764 035 $a(Au-PeEL)EBL4830573 035 $a(CaPaEBR)ebr11369158 035 $a(CaONFJC)MIL1003100 035 $a(OCoLC)982010838 035 $a(EXLCZ)993710000001123496 100 $a20170419h20172017 uy 0 101 0 $aeng 135 $aurcnu|||||||| 181 $2rdacontent 182 $2rdamedia 183 $2rdacarrier 200 00$aStem cells $efrom drug to drug discovery /$fKhawaja Husnain Haider (editor) 210 1$aBerlin, [Germany] ;$aBoston, [Massachusetts] :$cDe Gruyter,$d2017. 210 4$d?2017 215 $a1 online resource (232 pages) $cillustrations 311 $a3-11-049628-3 311 $a3-11-049376-4 320 $aIncludes bibliographical references at the end of each chapters and index. 327 $tFrontmatter -- $tPreface -- $tContents -- $tContributing authors -- $tList of abbreviations -- $t1. Human pluripotent stem-cell-derived vascular cells: in vitro model for angiogenesis and drug discovery / $rGopu, Sriram / Tong, Cao -- $t2. Role of small molecules in the cardiac differentiation of mesenchymal stem cells / $rKhan, Irfan / Naeem, Nadia / Ali, Anwar / Salim, Asmat -- $t3. MicroRNAs as modulators of endothelial differentiation of stem cells: role in vascular regenerative medicine / $rGündüz, Dursun / Aslam, Muhammad -- $t4. Cells for the repair of damaged skin and cartilage / $rRiazuddin, Sheikh / Mehmood, Azra / Latief, Noreen / Tarar, Moazzam Nazeer -- $t5. The skeletal muscle stem cells: biology and use in regenerative medicine / $rAlsharidah, Mansour Saleh / Haider, Khawaja Husnain / Abdalla, Elmuataz Elmansi / Mohammed, Salman Afroze Azmi -- $t6. Nanoparticle-based genetic engineering of mesenchymal stem cells / $rGuo, Changfa / Zhu, Kai / Haider, Khawaja Husnain -- $t7. Neural stem cells in regenerative medicine / $rHosseini, Seyed Mojtaba / Ziaee, Seyyed Mohyeddin / Tabeshmehr, Parisa -- $t8. "Paracrining" the heart with stem cells / $rLei, Ye / Haider, Khawaja Husnain -- $tIndex 330 $aStem cell based therapy is a 21st century approach of therapeutic intervention which epitomizes a shift from conventional symptomatic treatment strategy to addressing the root cause of the disease process. This is especially a hope for the patients suffering from diseases such as Alzheimer, diabetes, myocardial infarction and other diseases which have always been considered as incurable. Moreover, stem cells provide excellent in vitro disease models for drug development. This book is a compilation of the bench experience of experts from various research labs involved in the cutting edge area of research, describing the use of stem cells both as part of the combinatorial therapeutic intervention approach and as tools (disease model) during drug development. 606 $aStem cells 615 0$aStem cells. 676 $a616.02774 702 $aHaider$b Khawaja Husnain 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910792730803321 996 $aStem cells$9786361 997 $aUNINA