LEADER 03230nam 2200397 450 001 9910633979303321 005 20230323195100.0 010 $a1-80355-055-4 035 $a(CKB)5700000000338567 035 $a(NjHacI)995700000000338567 035 $a(EXLCZ)995700000000338567 100 $a20230323d2022 uy 0 101 0 $aeng 135 $aur||||||||||| 181 $ctxt$2rdacontent 182 $cc$2rdamedia 183 $acr$2rdacarrier 200 00$aExtracellular Vesicles $eRole in Diseases, Pathogenesis and Therapy /$fedited by Manash K. Paul 210 1$aLondon :$cIntechOpen,$d2022. 215 $a1 online resource (338 pages) 225 1 $aPhysiology 311 $a1-80355-054-6 327 $a1. Introductory Chapter: Role of Extracellular Vesicles in Human Diseases and Therapy -- 2. Mechanisms of Extracellular Vesicle Biogenesis, Cargo Loading, and Release -- 3. Extracellular Vesicles and Their Interplay with Biological Membranes -- 4. Morphology and Formation Mechanisms of Cellular Vesicles Harvested from Blood -- 5. High-Throughput Single Extracellular Vesicle Profiling -- 6. Extracellular Vesicles as Intercellular Communication Vehicles in Regenerative Medicine -- 7. Roles of Extracellular Vesicles in Human Reproduction -- 8. Exosomes and HIV-1 Association in AIDS-Defining Patients -- 9. The Role of Extracellular Vesicles in Immunomodulation and Pathogenesis of Leishmania and Other Protozoan Infections -- 10. Retracted: The Role of Extracellular Vesicles in the Progression of Tumors towards Metastasis -- 11. Exosomes in Cancer Diagnosis and Radiation Therapy -- 12. Diversity of Extracellular Vesicles (EV) in Plasma of Cancer Patients -- 13. Extracellular Vesicles as Biomarkers and Therapeutic Targets in Cancers -- 14. Extracellular Vesicles and Ovarian Cancer -- 15. Engineering of Extracellular Vesicles as Nano Therapy for Breast Cancer -- 16. Roles of Extracellular Vesicles in Cancer Metastasis -- 17. Tumor-Derived Exosome and Immune Modulation -- 18. Extracellular Vesicles for Cancer Immunotherapy: Biomarkers and Beyond. 330 $aExtracellular vesicles (EVs) are nanoscale vesicles secreted by cells that mediate horizontal cargo transport from donor to recipient cell, thereby establishing cell-cell communication and signaling. This book provides critical information on the fundamentals of EVs, their roles in diseases like cancer, and their use in disease management. The chapters emphasize the emerging data confirming the role of EVs in the pathogenesis of diseases and discuss the scientific advances that have made it feasible to characterize and engineer EVs, leading to their use as tools in biomarker discovery and disease diagnosis, prognosis, therapeutic application, and theranostics. This volume is a valuable resource for basic biologists, translational scientists, and clinicians. 410 0$aEBE biology program.$nUnit 4,$pPhysiology. 517 $aExtracellular Vesicles 606 $aLiposomes 615 0$aLiposomes. 676 $a571.655 702 $aPaul$b Manash K. 801 0$bNjHacI 801 1$bNjHacl 906 $aBOOK 912 $a9910633979303321 996 $aExtracellular vesicles$91765275 997 $aUNINA LEADER 03667nam 2200553 450 001 9910792582703321 005 20230126214827.0 010 $a0-8229-8154-8 035 $a(CKB)3710000000963783 035 $a(MiAaPQ)EBC4768831 035 $a(OCoLC)965157699 035 $a(MdBmJHUP)muse54075 035 $a(Au-PeEL)EBL4768831 035 $a(CaPaEBR)ebr11316638 035 $a(CaONFJC)MIL978582 035 $a(EXLCZ)993710000000963783 100 $a20161222h20162016 uy 0 101 0 $aeng 135 $aurcnu|||||||| 181 $2rdacontent 182 $2rdamedia 183 $2rdacarrier 200 14$aThe force of custom $elaw and the ordering of everyday life in Kyrgyzstan /$fJudith Beyer 210 1$aPittsburgh, Pennsylvania :$cUniversity of Pittsburgh Press,$d2016. 210 4$dİ2016 215 $a1 online resource (273 pages) $cillustrations, maps 225 1 $aCentral Eurasia in Context 311 $a0-8229-6420-1 320 $aIncludes bibliographical references and index. 330 $a"Judith Beyer presents a finely textured ethnographic study that sheds new light on the legal and moral ordering of everyday life in northwestern Kyrgyzstan. Beyer shows how local Kyrgyz negotiate proper behavior and regulate disputes by invoking custom, known to the locals as salt. While salt is presented as age-old tradition, its invocation needs to be understood as a highly developed and flexible rhetorical strategy that people adapt to suit political, legal, economic, and religious environments"--$cProvided by publisher. 330 $a"The Force of Custom presents a finely textured ethnographic study that sheds new light on the legal and moral ordering of everyday life in northwestern Kyrgyzstan. Through her extensive fieldwork and firsthand experience, Judith Beyer reveals how Kyrgyz in Talas province negotiate proper behavior and regulate disputes by invoking custom, known to the locals as salt. While salt is presented as age-old tradition, its invocation is shown to be a highly developed and flexible rhetorical strategy that people adapt in order to meet the challenges of contemporary political, legal, economic, and religious environments. Officially, codified state law should take precedence when it comes to dispute resolution, yet the unwritten laws of salt and the increasing importance of Islamic law provide the standards for ordering everyday life. As Beyer further demonstrates, interpretations of both Islamic and state law are also intrinsically linked to salt. By interweaving case studies on kinship, legal negotiations, festive events, mourning rituals, and political and business dealings, Beyer shows how salt is the binding element in rural Kyrgyz social life and how it is used to explain and negotiate moral behavior and to postulate communal identity. In this way, salt provides a time-tested, sustainable source of authentication that defies changes in government and the shifting tides of religious movements"--$cProvided by publisher. 410 0$aCentral Eurasia in context. 606 $aKyrgyz$xEthnic identity$xHistory 606 $aEthnology$zKyrgyzstan 606 $aNational characteristics, Kyrgyz 607 $aKyrgyzstan$xSocial life and customs 615 0$aKyrgyz$xEthnic identity$xHistory. 615 0$aEthnology 615 0$aNational characteristics, Kyrgyz. 676 $a390.095843 686 $aSOC002010$aHIS050000$2bisacsh 700 $aBeyer$b Judith$01480607 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910792582703321 996 $aThe force of custom$93697307 997 $aUNINA