LEADER 04305nam 2200625 a 450 001 9910792343303321 005 20230721015813.0 010 $a0-309-17731-6 010 $a0-309-13122-7 035 $a(CKB)2670000000015723 035 $a(OCoLC)568026960 035 $a(CaPaEBR)ebrary10290047 035 $a(SSID)ssj0000340375 035 $a(PQKBManifestationID)11256725 035 $a(PQKBTitleCode)TC0000340375 035 $a(PQKBWorkID)10387464 035 $a(PQKB)10262855 035 $a(MiAaPQ)EBC3378479 035 $a(Au-PeEL)EBL3378479 035 $a(CaPaEBR)ebr10290047 035 $a(OCoLC)923280208 035 $a(EXLCZ)992670000000015723 100 $a20090928d2009 uy 0 101 0 $aeng 135 $aurcn||||||||| 181 $ctxt 182 $cc 183 $acr 200 00$aMicrobial evolution and co-adaptation$b[electronic resource] $ea tribute to the life and scientific legacies of Joshua Lederberg : workshop summary /$frapporteurs, David A. Relman ... [et al.] 210 $aWashington, D.C. $cNational Academies Press$d2009 215 $a1 online resource (329 p.) 300 $aBibliographic Level Mode of Issuance: Monograph 311 $a0-309-13121-9 320 $aIncludes bibliographical references. 327 $aWorkshop overview -- Appendix: WO-1. Infectious history / Joshua Lederberg -- The life and legacies of Joshua Lederberg -- Reflections on the career of Joshua Lederberg / David A. Hamburg -- Joshua Lederberg remembered / Stephen S. Morse -- The life and impact of a legend-Joshua Lederberg / Adel Mahmoud -- Microbial ecology and ecosystems -- War and peace: humans and their microbiome / David A. Relman -- Deciphering the complex molecular dialogue of symbiosis: Esperanto or polyglot? / Margret McFall-Ngai -- Pathogen evolution -- Bacterial pathogenicity: an historical and experimental perspective / Stanley Falkow -- Evolution of bacterial-host interactions: virulence and the immune overresponse / Elisa Margolis and Bruce R. Levin -- Antibiotic resistance: origins and countermeasures -- Antibiotic resistance and the future of antibiotics / Julian Davies -- Microbial drug resistance: an old problem in need of new solutions / Stanley N. Cohen -- Expanding the microbial universe: metagenomics and microbial community dynamics / Jo Handelsman -- Infectious disease emergence: past, present, and future -- Emerging infections: condemned to repeat? / Stephen S. Morse -- Ecological origins of novel human pathogens / Mark Woolhouse and Eleanor Gaunt -- Genomic evolvability and the origin of novelty: studying the past, interpreting the present, and predicating the future / Jonathan A. Eisen -- Can we predict future trends in disease emergence? / Peter Daszak -- Appendices: A. Agenda -- B. Acronyms -- C. Glossary -- D. Forum member biographies. 330 $a"Dr. Joshua Lederberg - scientist, Nobel laureate, visionary thinker, and friend of the Forum on Microbial Threats - died on February 2, 2008. It was in his honor that the Institute of Medicine's Forum on Microbial Threats convened a public workshop on May 20-21, 2008, to examine Dr. Lederberg's scientific and policy contributions to the marketplace of ideas in the life sciences, medicine, and public policy. The resulting workshop summary, Microbial Evolution and Co-Adaptation, demonstrates the extent to which conceptual and technological developments have, within a few short years, advanced our collective understanding of the microbiome, microbial genetics, microbial communities, and microbe-host-environment interactions." 606 $aMicroorganisms$xEvolution$vCongresses 606 $aCommunicable diseases$vCongresses 606 $aEvolution$vCongresses 606 $aAdaptation (Biology)$vCongresses 615 0$aMicroorganisms$xEvolution 615 0$aCommunicable diseases 615 0$aEvolution 615 0$aAdaptation (Biology) 676 $a579/.135 701 $aLederberg$b Joshua$095738 701 $aRelman$b David A$01478506 712 02$aInstitute of Medicine (U.S.).$bForum on Microbial Threats. 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910792343303321 996 $aMicrobial evolution and co-adaptation$93810056 997 $aUNINA