LEADER 05634nam 2200661 450 001 9910792224303321 005 20200520144314.0 010 $a0-12-397769-X 010 $a0-12-397175-6 035 $a(CKB)2560000000301458 035 $a(EBL)1879380 035 $a(SSID)ssj0001538613 035 $a(PQKBManifestationID)11835930 035 $a(PQKBTitleCode)TC0001538613 035 $a(PQKBWorkID)11536590 035 $a(PQKB)10562552 035 $a(MiAaPQ)EBC1879380 035 $a(Au-PeEL)EBL1879380 035 $a(CaPaEBR)ebr11058656 035 $a(CaONFJC)MIL111930 035 $a(OCoLC)898101400 035 $a(PPN)198602553 035 $a(EXLCZ)992560000000301458 100 $a20150605h20152015 uy| 0 101 0 $aeng 135 $aur|n|---||||| 181 $ctxt 182 $cc 183 $acr 200 00$aKnobil and Neill's physiology of reproduction /$feditors-in-chief, Tony M. Plant and Anthony J. Zeleznik, University of Pittsburgh, Pittsburgh, PA, USA ; associate editors, David F. Albertini, Kansas University Medical Center, Kansas City, KS, USA [and five others] 205 $aFourth edition. 210 1$aAmsterdam :$cElsevier,$d[2015] 210 4$dİ2015 215 $a1 online resource (10218 p.) 300 $aDescription based upon print version of record. 320 $aIncludes bibliographical references and index. 327 $aCover image; Title page; Table of Contents; Copyright; Illustration Credits; Contributors; Introduction; Preface; Foreword by Roy O. Greep; Foreword by M. Susan Smith; Volume 1; Section I. Gametes, Fertilization and Embryogenesis; Chapter 1. Mammalian Meiosis; Introduction; Effects of Gonadal Hormones: Cellular and Molecular Mechanisms; Other Central Transmitters in the Metabolic Control of Reproduction; Conclusion; Conclusion; Conclusion; Chapter 2. The Mammalian Oocyte; Introduction; Components of Parental Care; Measures of Penile Function; Anatomy and Physiology of Sexual Sensory Systems 327 $aSteroid Hormones of the PlacentaChapter 3. The Spermatozoon; Introduction; Evolutionary Significance of Mate Choice; Food Intake and Metabolism in Pregnancy; Fetal Programming and the Onset of Puberty; Milk Ejection; Chapter 4. Fertilization in Mammals; Introduction; Delayed Implantation (Mammalian Diapause); Imprinting Disorders; Sexual Differentiation in Different Contexts; Hypotheses Linking Hypothalamic T3 Content to Hypothalamic Neural Changes Driving Seasonal Breeding: A Pivotal Role for Tanycytes?; Milk Composition and its Regulation; Addendum; Chapter 5. Gamete and Zygote Transport 327 $aIntroductionConsiderations for Understanding the Hormonal Regulation of Maternal Care; Immunological Origins of Pregnancy Disorders; Brain Areas Implicated in Control of Male Sexual Behavior; Chapter 6. Preimplantation Embryo Development and Primordial Germ Cell Lineage Specification; Introduction; Sensory Control of Maternal Care; Other Epigenetic Mechanisms; Brain Control of Maternal Behaviors; Regenerative Potential of Spermatogonial Stem Cells and Translation to the Clinic; Chapter 7. Sex Determination and Differentiation; Introduction; Hormones Most Significant for Paternal Behaviors 327 $aEffects of Systemically or Intracerebroventricularly Administered DrugsSection II. Gonadal Steroids, Pituitary and Hypothalamus; Chapter 8. Human Steroid Biosynthesis; Introduction; General Concepts; The Conversion of Cholesterol to Pregnenolone and Mitochondrial Steroid Metabolism; Steroid Hydroxylation and the Microsomal P450 Enzymes; HSDs, the Terminal Steps, and Peripheral Metabolism; Steroid Sulfonation; Steroid Degradation and Excretion; Pathways; Comparison with Other Species; Conclusion; Chapter 9. Gonadal Steroid Action; Introduction; Transcriptional Actions of Gonadal Steroids 327 $aNontranscriptional Effectors of Gonadal SteroidsSteroid Signaling via Membrane Receptors; Coregulators and Gonadal Steroid Physiology; Informatic Approaches and Transcriptional Regulation by Gonadal Steroids; Conclusion; Chapter 10. Gonadotropes and Gonadotropin-Releasing Hormone Signaling; Introduction; Areas of Emerging Interest; Chapter 11. Physiology of the Adult Gonadotropin-Releasing Hormone Neuronal Network; Introduction; Activation of Male Sexual Behavior by Gonadal Hormones; Male Reproductive Aging; Regulation of the Adult Prostate; Conclusion; Conclusion 327 $aChapter 12. Hypothalamic Control of Prolactin Secretion, and the Multiple Reproductive Functions of Prolactin 330 $aThe Fourth Edition of Knobil & Neill continues to serve as a reference aid for research, to provide the historical context to current research, and most importantly as an aid for graduate teaching on a broad range of topics in human and comparative reproduction. In the decade since the publication of the last edition, the study of reproductive physiology has undergone monumental changes. Chief among these advances are in the areas of stem cell development, signaling pathways, the role of inflammation in the regulatory processes in the various tissues, and the integration of new animal models 606 $aReproduction 606 $aMammals$xPhysiology 615 0$aReproduction. 615 0$aMammals$xPhysiology. 676 $a573.619 702 $aPlant$b T. M$g(Tony M.), 702 $aZeleznik$b Anthony J. 702 $aAlbertini$b David F. 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910792224303321 996 $aKnobil and Neill's physiology of reproduction$93868958 997 $aUNINA