LEADER 04188nam 2200577 450 001 9910495234303321 005 20230425143348.0 010 $a3-319-89497-8 024 7 $a10.1007/978-3-319-89497-3 035 $a(CKB)4100000011996290 035 $a(DE-He213)978-3-319-89497-3 035 $a(MiAaPQ)EBC6696320 035 $a(Au-PeEL)EBL6696320 035 $a(OCoLC)1263872356 035 $a(PPN)257353607 035 $a(EXLCZ)994100000011996290 100 $a20220425d2021 uy 0 101 0 $aeng 135 $aurnn#008mamaa 181 $ctxt$2rdacontent 182 $cc$2rdamedia 183 $acr$2rdacarrier 200 00$aPolyendocrine disorders and endocrine neoplastic syndromes /$fAnnamaria Colao, Marie-Lise Jaffrain-Rea, Albert Beckers, editors 205 $a1st ed. 2021. 210 1$aCham, Switzerland :$cSpringer,$d[2021] 210 4$d©2021 215 $a1 online resource (44 illus., 28 illus. in color. eReference.) 225 1 $aEndocrinology (Series : 2018- ) 311 $a3-319-89496-X 320 $aIncludes bibliographical references and index. 327 $aIntroduction.-Auto-immune polyglandular syndromes (APS): an overview -- The natural history of APS1: pathogenesis and long term follow-up -- The genetics of AIRE: an update -- Auto-antibodies in polyendocrine auto-immune disorders: an update -- Rare forms of endocrine and systemic auto-immune disorders: IPEX and ?other POEMS? -- Auto-immune endocrine diseases and cancer immunotherapy -- Part 2: MEN1: an update on molecular diagnosis and clinical implications -- MEN2: an update on molecular diagnosis and clinical implications -- MEN4 and other MEN1-like syndrome -- Genetic alterations in the cAMP pathway: MAS, Carney complex (and AIP?) -- Endocrine tumours associated with SDHx mutations: pheochromocytomas, paragangliomas and pituitary adenomas -- Endocrine tumours in complex genetic disorders: lessons from pheochromocytomas and hyperparathyroidism. 330 $aThis comprehensive reference book is meant to support clinicians in the diagnosis and treatment of polyendocrine diseases and endocrine neoplastic syndromes. Although a large majority of endocrine diseases present as sporadic cases, an increasing proportion can be identified as part of a polyendocrine or systemic syndrome. These include autoimmune endocrine diseases, which may be part of autoimmune polyendocrine disorders (APS) or rare complex disorders such as POEMS (polyneuropathy, organomegaly, endocrinopathy, M-protein and skin changes) or IPEX (immune dysregulation, polyendocrinopathy, enteropathy, X-linked) syndromes. On the other hand, endocrine tumors may develop in a variety of clinical conditions, including multiple endocrine neoplasia (MEN) syndromes, syndromic diseases such as McCune Albright or Carney?s complex, or peculiar familial associations such as pheochromocytoma/paraganglioma syndromes. The book discusses the significant advances that have been made in the clinical and genetic characterization of such entities, with major implications in terms of diagnosis and clinical management - with special attention to emerging syndromes, familial screening , multidisciplinarity and multimodal treatment. This volume is intended for clinicians, residents, specialists and physicians involved in the diagnosis and treatment of affected patients, including specialists in endocrinology, internal medicine, oncology , genetics and imaging. . 410 0$aEndocrinology (Series : 2018- ) 606 $aEndocrine glands$xDiseases$xDiagnosis 606 $aMalalties de les glàndules endocrines$2thub 606 $aDiagnòstic$2thub 608 $aLlibres electrònics$2thub 615 0$aEndocrine glands$xDiseases$xDiagnosis. 615 7$aMalalties de les glàndules endocrines 615 7$aDiagnòstic 676 $a616.4075 702 $aColao$b Annamaria 702 $aJaffrain-Rea$b Marie-Lise 702 $aBeckers$b Albert 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910495234303321 996 $aPolyendocrine Disorders and Endocrine Neoplastic Syndromes$91742350 997 $aUNINA LEADER 01374nam 2200457 450 001 9910792138203321 005 20230807203857.0 010 $a1-4698-8952-8 035 $a(CKB)2560000000261875 035 $a(SSID)ssj0001380193 035 $a(PQKBManifestationID)12537778 035 $a(PQKBTitleCode)TC0001380193 035 $a(PQKBWorkID)11367294 035 $a(PQKB)11360297 035 $a(MiAaPQ)EBC6897912 035 $a(Au-PeEL)EBL6897912 035 $a(EXLCZ)992560000000261875 100 $a20220706d2015 uy 0 101 0 $aeng 135 $aurcnu|||||||| 181 $ctxt 182 $cc 183 $acr 200 10$aBreast imaging and pathologic correlations $ea pattern-based approach /$fDianne Georgian-Smith, Thomas Lawton 210 1$aPhiladelphia, Pennsylvania :$cWolters Kluwer,$d[2015] 210 4$d©2015 215 $a1 online resource (581 pages) 300 $aIncludes index. 311 $a1-4511-9269-X 606 $aBreast$xMagnetic resonance imaging 615 0$aBreast$xMagnetic resonance imaging. 676 $a618.1907548 700 $aGeorgian-Smith$b Dianne$01579886 702 $aLawton$b Thomas J. 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910792138203321 996 $aBreast imaging and pathologic correlations$93860276 997 $aUNINA