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100   $a20100811d2011      uy             0
101 0 $aeng
135   $aur|n|---|||||
181   $ctxt
182   $cc
183   $acr
200 00$aEpigenetics$b[electronic resource] $elinking genotype and phenotype in development and evolution /$fedited by Benedikt Hallgri?msson and Brian K. Hall
205   $a1st ed.
210   $aBerkeley $cUniversity of California Press$dc2011
215   $a1 online resource (469 p.)
300   $aDescription based upon print version of record.
311   $a0-520-26709-5 
320   $aIncludes bibliographical references and index.
327   $tFrontmatter --$tContents --$tContributors --$t1. Introduction --$t2. A Brief History of the Term and Concept Epigenetics --$t3. Heuristic Reductionism and the Relative significance of Epigenetic Inheritance in evolution --$t4. The Epigenetics of Genomic Imprinting: Core Epigenetic Processes are conserved in Mammals, Insects, and Plants --$t5. Methylation Mapping in Humans --$t6. Asexuality and Epigenetic Variation --$t7. Epigenesis, Preformation, and the Humpty Dumpty Problem --$t8. A Principle of Developmental Inertia --$t9. The Role of Epigenetics in Nervous System Development --$t10. Morphogenesis of Pigment Patterns: Experimental and Modeling Approaches --$t11. Epigenetic Interactions of the Cardiac Neural Crest --$t12. Epigenetics in Bone and cartilage Development --$t13. Muscle-Bone Interactions and the Development of skeletal Phenotype: Jaw muscles and the skull --$t14. Evolution of the Apical Ectoderm in the Developing Vertebrate Limb --$t15. Role of Skeletal Muscle in the Epigenetic Shaping of Organs, Tissues, and Cell Fate Choices --$t16. Epigenetic Integration, Complexity, and Evolvability of the Head: Rethinking the Functional Matrix Hypothesis --$t17. Epigenetic Interactions: The Developmental Route to Functional Integration --$t18. Epigenetic Contributions to Adaptive Radiation: Insights from Threespine Stickleback --$t19. Learning, Developmental Plasticity, and the Rate of Morphological Evolution --$t20. Epigenetics: Adaptation or Contingency? --$t21. The Epigenetics of Dysmorphology. Craniosynostosis as an Example --$t22. Epigenetics of Human Disease --$t23. Epigenetics: The Context of Development --$tIndex
330   $aIlluminating the processes and patterns that link genotype to phenotype, epigenetics seeks to explain features, characters, and developmental mechanisms that can only be understood in terms of interactions that arise above the level of the gene. With chapters written by leading authorities, this volume offers a broad integrative survey of epigenetics. Approaching this complex subject from a variety of perspectives, it presents a broad, historically grounded view that demonstrates the utility of this approach for understanding complex biological systems in development, disease, and evolution. Chapters cover such topics as morphogenesis and organ formation, conceptual foundations, and cell differentiation, and together demonstrate that the integration of epigenetics into mainstream developmental biology is essential for answering fundamental questions about how phenotypic traits are produced.
606   $aPhenotype
606   $aEpigenesis
606   $aGenotype-environment interaction
606   $aGenetic regulation
606   $aDevelopmental genetics
606   $aEvolutionary genetics
610   $aadaptation.
610   $aallele.
610   $aasymmetry.
610   $abiological systems.
610   $abiology.
610   $abone morphology.
610   $abrain.
610   $acardiac neural crest.
610   $acell differentiation.
610   $achromatin.
610   $adevelopmental biology.
610   $adisease.
610   $adysmorphology.
610   $aepigenetics.
610   $aevolution.
610   $aevolutionary biology.
610   $agenetic assimilation.
610   $agenetic traits.
610   $agenetics.
610   $agenotype.
610   $ahealthcare.
610   $alife sciences.
610   $amandible.
610   $amedicine.
610   $amorphogenesis.
610   $anonfiction.
610   $aorgan formation.
610   $aphenotype.
610   $ascience.
610   $atechnology.
610   $atooth development.
610   $awaddington.
615  0$aPhenotype.
615  0$aEpigenesis.
615  0$aGenotype-environment interaction.
615  0$aGenetic regulation.
615  0$aDevelopmental genetics.
615  0$aEvolutionary genetics.
676   $a576.5/3
686   $aWG 1940$2rvk
700   $aHallgri?msson$b Benedikt$0446539
701   $aHallgri?msson$b Benedikt$0446539
701   $aHall$b Brian Keith$f1941-$0446538
801  0$bMiAaPQ
801  1$bMiAaPQ
801  2$bMiAaPQ
906   $aBOOK
912   $a9910791806903321
996   $aEpigenetics$93699286
997   $aUNINA