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100   $a20140414h20142014  uy             0
101 0 $aeng
135   $aur|n|---|||||
181   $ctxt
182   $cc
183   $acr
200 10$aMolecular and cellular toxicology $ean introduction /$fDr. Lesley A. Stanley
210  1$aChichester, England :$cWiley Blackwell,$d2014.
210  4$d2014
215   $a1 online resource (435 p.)
225 1 $aNew York Academy of Sciences 
300   $aIncludes bibliographical references and index
311   $a1-119-95206-9 
311   $a1-306-57172-3 
320   $aIncludes bibliographical references at the end of each chapters and index.
327   $aBackground to molecular and cellular toxicology -- Individual susceptibility to toxic chemicals -- Omics techniques -- In vitro methods for predicting in vivo toxicity -- In vitro methods for absorption, distribution, metabolism and excretion -- In silico methods and structure-activity relationships -- Transgenic animal models for ADME and systemic toxicity -- Genotoxicity and its measurement -- Oncogenes and the identification of human carcinogens -- Emerging techniques.
330   $aToxicology is the study of the adverse effects of chemical, physical, or biological agents on people, animals, and the environment. Toxicologists are trained to investigate, interpret, and communicate the nature of those effects.   Over the last ten years the subject of toxicology has changed dramatically, moving from a discipline which was once firmly wedded to traditional methods to one which is keen to embrace the innovative techniques emerging from the developing fields of cell culture and molecular biology. There is an acute need for this to be reflected in a paradigm shift which
410  0$aNew York Academy of Sciences 
606   $aToxicity testing$vMethods
606   $aMolecular biology
606   $aXenobiotics$xtoxicity
615  0$aToxicity testing
615  0$aMolecular biology.
615  0$aXenobiotics$xtoxicity.
676   $a615.9/07
686   $a491.59$2njb/09
686   $aQV 602$2njb/09
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700   $aStanley$b Lesley$01525396
801  0$bMiAaPQ
801  1$bMiAaPQ
801  2$bMiAaPQ
906   $aBOOK
912   $a9910790941303321
996   $aMolecular and cellular toxicology$93766761
997   $aUNINA