LEADER 03071nam 22006971 450 001 9910790819103321 005 20230213212806.0 010 $a3-11-175202-X 010 $a3-11-080416-6 024 7 $a10.1515/9783110804164 035 $a(CKB)2550000001178359 035 $a(OCoLC)868974018 035 $a(CaPaEBR)ebrary10789588 035 $a(SSID)ssj0001054522 035 $a(PQKBManifestationID)11613291 035 $a(PQKBTitleCode)TC0001054522 035 $a(PQKBWorkID)11133792 035 $a(PQKB)10459988 035 $a(MiAaPQ)EBC3044556 035 $a(DE-B1597)43117 035 $a(OCoLC)979969844 035 $a(DE-B1597)9783110804164 035 $a(Au-PeEL)EBL3044556 035 $a(CaPaEBR)ebr10789588 035 $a(CaONFJC)MIL558547 035 $a(OCoLC)922947755 035 $a(EXLCZ)992550000001178359 100 $a19830126h19801980 uy 0 101 0 $aeng 135 $aurcnu|||||||| 181 $ctxt 182 $cc 183 $acr 200 10$aSelf and non-self in early Buddhism /$fJoaqui?n Pe?rez Remo?n 205 $aReprint 2012 210 1$aThe Hague ;$aNew York :$cMouton,$d[1980] 210 4$dİ1980 215 $a1 online resource (424 p.) 225 0 $aReligion and Reason ;$v22 225 0$aReligion and reason ;$v22 300 $aOriginally presented as the author's thesis (doctoral--University of Bombay) under the title: The Anattava?da in the Suttapit?aka. 311 $a90-279-7987-1 311 $a1-306-27296-3 320 $aIncludes bibliographical references (pages 384-387) and index. 327 $tFrontmatter -- $tPreface -- $tContents -- $tList of Sources and Abbreviations -- $tIntroduction -- $tPART ONE: The Existential Self -- $t1. Preliminary Remarks -- $t2. Atta as Man's Highest Value -- $t3. The Self as the Moral Agent -- $t4. The Self and Moral Evil -- $t5. Towards Perfection -- $t6. The Self and Perfection -- $t7. The Self as Related to Kamma and Rebirth -- $t8. A Brief General Assessment of the First Part -- $tPART TWO: The Metaphysical Self -- $t9. The Doctrine of Anatt? Can Coexist With the Reality of Att? -- $t10. The Doctrine of Anatt? Taught Through the Denial of Positive Terms -- $t11. The Doctrine of Non-Self Taught Through the Predication of the Negative Term Anatt? -- $t12. Asmim?na, Sakk?yadi??hi, Sassatav?da and Ucchedav?da -- $t13. Self and Non-self After Liberation -- $t14. Recapitulation -- $tNotes -- $tSelected Bibliography -- $tGlossary of terms -- $tTable of Scriptural Passages Commented or Quoted -- $tIndex of Names and Subjects 606 $aA?tman 606 $aAna?tman 606 $aBuddhism$xDoctrines 615 0$aA?tman. 615 0$aAna?tman. 615 0$aBuddhism$xDoctrines. 676 $a294.3/422 686 $aBE 8520$2rvk 700 $aPe?rez Remo?n$b Joaqui?n$01480928 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910790819103321 996 $aSelf and non-self in early Buddhism$93697747 997 $aUNINA LEADER 05553nam 2200493 450 001 9910830599403321 005 20230809224943.0 010 $a1-119-38440-0 010 $a1-119-38442-7 010 $a1-119-38443-5 035 $a(CKB)3710000001633585 035 $a(DLC) 2017022128 035 $a(MiAaPQ)EBC4914178 035 $a(EXLCZ)993710000001633585 100 $a20170811h20172017 uy 0 101 0 $aeng 135 $aur||||||||||| 181 $ctxt$2rdacontent 182 $cn$2rdamedia 183 $anc$2rdacarrier 200 00$aAnalytical characterization of biotherapeutics /$fedited by Jennie R. Lill, Wendy N. Sandoval 210 1$aHoboken, New Jersey :$cWiley,$d2017. 210 4$dİ2017 215 $a1 online resource 311 $a1-119-05310-2 320 $aIncludes bibliographical references at the end of each chapters and index. 327 $aMachine generated contents note: Dedication Chapter 1: Introduction to Biotherapeutics Jennie R. Lill Chapter 2: Mass Spectrometric Characterization of Recombinant Proteins Corey E Bakalarski, Wendy N Sandoval & Jennie R Lill Chapter 3: Characterizing the Termini of Recombinant Proteins Nestor Solis, Christopher M. Overall Chapter 4: Assessing activity & conformation of recombinant proteins Diego Ellerman, Till Maurer, Justin M. Scheer Chapter 5: Structural Characterization of Recombinant Proteins & Antibodies Paola Di Lello and Patrick Lupardus Chapter 6: Antibody de novo sequencing Natalie Castellana, Adrian Guthals Chapter 7: Characterization of Antibody Drug Conjugates Yichin Liu Chapter 8: Characterization of Bi-Specific or other Hybrid molecules T. Noelle Lombana and Christoph Spiess Chapter 9: Bio-Repository Anne Baldwin, Kurt Schroeder, Lovejit Singh, Karen Billeci Chapter 10: Characterization of Manufacturing Host-Cell Contaminant Proteins Denise Krawitz, Jason Rouse, Justin Sperry, Wendy Sandoval, Martin Vanderlaan Chapter 11: Analytical Tools for Biologics Molecular Assessment Wilson Phung , Wendy Sandoval, Robert F Kelley & Jennie R Lill Chapter 12: Glycan Characterization: Determining the Structure, Distribution, and Localization of Glycoprotein Glycans John Briggs INDEX. 330 $a"The definitive guide to the myriad analytical techniques available to scientists involved in biotherapeutics research Analytical Characterization of Biotherapeutics covers all current and emerging analytical tools and techniques used for the characterization of therapeutic proteins and antigen reagents. From basic recombinant antigen and antibody characterization, to complex analyses for increasingly complex molecular designs, the book explores the history of the analysis techniques and offers valuable insights into the most important emerging analytical solutions. In addition, it frames critical questions warranting attention in the design and delivery of a therapeutic protein, exposes analytical challenges that may occur when characterizing these molecules, and presents a number of tested solutions. The first single-volume guide of its kind, Analytical Characterization of Biotherapeutics brings together contributions from scientists at the leading edge of biotherapeutics research and manufacturing. Key topics covered in-depth include the structural characterization of recombinant proteins and antibodies, antibody de novo sequencing, characterization of antibody drug conjugates, characterization of bi-specific or other hybrid molecules, characterization of manufacturing host-cell contaminant proteins, analytical tools for biologics molecular assessment, and more. Each chapter is written by a recognized expert or experts in their field who discuss current and cutting edge approaches to fully characterizing biotherapeutic proteins and antigen reagents Covers the full range of characterization strategies for large molecule based therapeutics Provides an up-to-date account of the latest approaches used for large molecule characterization Chapters cover the background needed to understand the challenges at hand, solutions to characterize these large molecules, and a summary of emerging options for analytical characterization, Analytical Characterization of Biotherapeutics is an up-to-date resource for analytical scientists, biologists, and mass spectrometrists involved in the analysis of biomolecules, as well as scientists employed in the pharmaceuticals and biotechnology industries. Graduate students in biology and analytical science, and their instructors will find it to be fascinating and instructive supplementary reading.--$cProvided by publisher. 330 $a"This book covers all current and emerging analytical tools and techniques used for the characterization of therapeutic proteins and antigen reagents. From basic recombinant antigen and antibody characterization, to complex analyses for increasingly complex molecular designs, the book explores the history of the analysis techniques and offers valuable insights into the most important emerging analytical solutions"--$cProvided by publisher. 606 $aProteins$xTherapeutic use 606 $aProteins$xAnalysis 615 0$aProteins$xTherapeutic use. 615 0$aProteins$xAnalysis. 676 $a615.7 686 $aSCI013010$2bisacsh 702 $aLill$b Jennie R. 702 $aSandoval$b Wendy N. 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910830599403321 996 $aAnalytical characterization of biotherapeutics$94067193 997 $aUNINA