LEADER 05341nam 2200685Ia 450 001 9910789972003321 005 20230721014549.0 010 $a1-383-03492-3 010 $a1-283-58120-5 010 $a9786613893659 010 $a0-19-156708-6 010 $a0-19-160732-0 035 $a(CKB)2670000000154647 035 $a(EBL)845990 035 $a(OCoLC)778339706 035 $a(SSID)ssj0000614256 035 $a(PQKBManifestationID)12256818 035 $a(PQKBTitleCode)TC0000614256 035 $a(PQKBWorkID)10587784 035 $a(PQKB)11205731 035 $a(Au-PeEL)EBL845990 035 $a(CaPaEBR)ebr10581416 035 $a(CaONFJC)MIL389365 035 $a(MiAaPQ)EBC845990 035 $a(EXLCZ)992670000000154647 100 $a20061116d2007 uy 0 101 0 $aeng 135 $aur|n|---||||| 181 $ctxt 182 $cc 183 $acr 200 10$aEssential tremor$b[electronic resource] $ethe facts /$fMark Plumb, Peter Bain 210 $aOxford ;$aNew York $cOxford University Press$d2007 215 $a1 online resource (166 p.) 225 1 $aFacts 300 $aDescription based upon print version of record. 311 $a0-19-921127-2 320 $aIncludes bibliographical references (p. 135-144) and index. 327 $aContents; Preface; Foreword; Foreword; Acknowledgements; 1 What is essential tremor?; The history of essential tremor; The clinical definition of 'classical essential tremor'; Essential tremor and emotional stress; Essential tremor and physiological stress; Ageing-essential tremor as a progressive disease, but is it a neurodegenerative disorder?; Other symptoms in essential tremor; Cognitive ability; Walking; Eyesight and eye movement; Sense of smell; Hearing; Weight loss; Conclusion; 2 Living and coping with essential tremor; Severity; Response to medication; Diet-coffee and alcohol; Anxiety 327 $aCounsellingMy hands don't shake-a personal view by Mark Plumb; Get to know the facts about essential tremor; Early age of onset; Raising awareness in society; Repetitive training of the voluntary muscles; 3 The diagnosis of essential tremor; Diagnosis as a process of elimination; Essential tremor versus Parkinson's disease-a differential diagnosis; Hypokinetic versus hyperkinetic movement disorders; The dopamine active transport scan; Is essential tremor a family of related movement disorders?; Assessing tremor severity in essential tremor; Clinical rating scales 327 $a4 The treatment of essential tremorNerve cells-what are they?; The medications used to treat essential tremor; Beta-blockers; Primidone; Benzodiazepines; Gabapentin; Topiramate; Botulinum toxin; Naturally occurring chemicals; Alcohol (ethanol); Caffeine; Cannabis; Stereotactic brain surgery-thalamotomy and deep brain stimulation; Stereotactic surgical procedures; Surgical complications; Side effects; How does DBS work?; 5 Who gets essential tremor?; The prevalence of essential tremor in the general population; Essential tremor in families; Essential tremor as a dominant genetic trait 327 $aTwins in essential tremor-essential tremor is highly heritableIdentifying the essential tremor genes; Essential tremor is a complex inherited disorder; Genetic testing in essential tremor; 6 Possible causes of essential tremor; Essential tremor as a neurological disorder of the central nervous system; Tremor-related nerve cell activity; Imaging studies of the brain in essential tremor; Muscle contraction; The principles of voluntary movement; The thalamus and the control of voluntary movement; Linking tremor and anxiety in essential tremor 327 $aThe neural network and the control of voluntary movementEssential tremor may be a deficit of inhibitory (GABA) neurotransmitter; The GABA receptor; The GABA[sub(A)] ?1 receptor subunit knock-out essential tremor mouse; Implications for the dominant mode of inheritance of essential tremor in humans; Conclusions; 7 The future: what are the prospects of a cure for essential tremor?; Gene therapy; Stem cells; The stem cell controversy; Stem cell therapy in neurodegenerative disorders; Neural stem cells and Parkinson's disease; Animal models in stem cell therapy 327 $aGene and stem cell therapy in essential tremor 330 $aEssential Tremor is the most common movement disorder in the world, and affects between 4 and 40 people per 1000 of the population amongst all ethnic groups. Characterised by shaking hands, this disorder can affect the head, voice and legs, and is often made worse by physical and emotional stress.Essential Tremor: The Facts provides a comprehensive guide to understanding this disorder and minimising its impact upon the lives of sufferers, their friends and families.It begins with a close look at what essential tremor is and how it should be diagnosed, as well as details on who gets the disorde 410 0$aFacts (Oxford, England) 606 $aTremor 606 $aMovement disorders 615 0$aTremor. 615 0$aMovement disorders. 676 $a616.7 700 $aPlumb$b Mark$01566210 701 $aBain$b Peter$01566211 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910789972003321 996 $aEssential tremor$93836583 997 $aUNINA