LEADER 04904nam 2200625 a 450 001 9910789916903321 005 20230801222455.0 010 $a1-280-12320-6 010 $a9786613527066 010 $a0-309-21809-8 035 $a(CKB)2670000000176334 035 $a(EBL)3378955 035 $a(SSID)ssj0000647248 035 $a(PQKBManifestationID)11434964 035 $a(PQKBTitleCode)TC0000647248 035 $a(PQKBWorkID)10594030 035 $a(PQKB)10657801 035 $a(MiAaPQ)EBC3378955 035 $a(Au-PeEL)EBL3378955 035 $a(CaPaEBR)ebr10554801 035 $a(CaONFJC)MIL352706 035 $a(OCoLC)775688619 035 $a(EXLCZ)992670000000176334 100 $a20120509d2012 uy 0 101 0 $aeng 135 $aurcn||||||||| 181 $ctxt 182 $cc 183 $acr 200 10$aPrepositioning antibiotics for anthrax$b[electronic resource] /$fInstitute of Medicine of the National Academies ; Clare Stroud ... [et al.], editors 210 $aWashington, D.C. $cNational Academies Press$d2012 215 $a1 online resource (79 p.) 300 $a"Committee on Prepositioned Medical Countermeasures for the Public ; Board on Health Sciences Policy." 311 $a0-309-21808-X 320 $aIncludes bibliographical references and index. 327 $a""Front Matter""; ""Reviewers""; ""Preface""; ""Acknowledgments""; ""Contents""; ""Summary""; ""1 Introduction""; ""2 Antibiotics for Anthrax Postexposure Prophylaxis""; ""3 Current Dispensing Strategies for Medical Countermeasures for Anthrax""; ""4 Prepositioning Strategies""; ""5 A Decision-Aiding Framework""; ""6 Recommended Actions for Moving Forward""; ""Appendix A: Acronyms""; ""Appendix B: Public Meeting Agendas""; ""Appendix C: First-Order Model""; ""Appendix D: Commissioned Paper: A Cost and Speed Analysis of Strategies for Prepositioning Antibiotics for Anthrax"" 327 $a""Appendix E: Committee Biosketches""""Index"" 330 $a"If terrorists released Bacillus anthracis over a large city, hundreds of thousands of people could be at risk of the deadly disease anthrax-caused by the B. anthracis spores-unless they had rapid access to antibiotic medical countermeasures (MCM). Although plans for rapidly delivering MCM to a large number of people following an anthrax attack have been greatly enhanced during the last decade, many public health authorities and policy experts fear that the nation's current systems and plans are insufficient to respond to the most challenging scenarios, such as a very large-scale anthrax attack. The U.S. Department of Health and Human Services' Office of the Assistant Secretary for Preparedness and Response commissioned the Institute of Medicine to examine the potential uses, benefits, and disadvantages of strategies for repositioning antibiotics. This involves storing antibiotics close to or in the possession of the people who would need rapid access to them should an attack occur. Prepositioning antibiotics for anthrax reviews the scientific evidence on the time window in which antibiotics successfully prevent anthrax and the implications for decision making about prepositioning, describes potential prepositioning strategies, and develops a framework to assist state, local, and tribal public health authorities in determining whether prepositioning strategies would be beneficial for their communities. However, based on an analysis of the likely health benefits, health risks, and relative costs of the different prepositioning strategies, the book also develops findings and recommendations to provide jurisdictions with some practical insights as to the circumstances in which different prepositioning strategies may be beneficial. Finally, the book identifies federal- and national-level actions that would facilitate the evaluation and development of prepositioning strategies. Recognizing that communities across the nation have differing needs and capabilities, the findings presented in this report are intended to assist public health officials in considering the benefits, costs, and trade-offs involved in developing alternative prepositioning strategies appropriate to their particular communities."--Publisher's description. 606 $aAnthrax$xVaccination 606 $aPublic health 606 $aBiosecurity 615 0$aAnthrax$xVaccination. 615 0$aPublic health. 615 0$aBiosecurity. 676 $a616.956 701 $aStroud$b Clare$01478508 712 02$aNational Research Council (U.S.).$bCommittee on Prepositioned Medical Countermeasures for the Public. 712 02$aNational Research Council (U.S.).$bBoard on Health Sciences Policy. 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910789916903321 996 $aPrepositioning antibiotics for anthrax$93797478 997 $aUNINA