LEADER 01066nam--2200373---450- 001 990003136510203316 005 20080806115243.0 010 $a978-88-6036-256-8 035 $a000313651 035 $aUSA01000313651 035 $a(ALEPH)000313651USA01 035 $a000313651 100 $a20080806d2008----km-y0itay50------ba 101 $aita 102 $aIT 105 $a||||||||001yy 200 1 $aStoria del fuoco$edalla preistoria ai giorni nostri$fJohan Goudsblom 210 $aRoma$cDonzelli$d2008 215 $aXVII, 237 p.$d23 cm 225 2 $aVirgola$v46 410 0$12001$aVirgola 454 0$12001$aFire and civilization$925437 606 0 $aFuoco$xUtilizzazione$xStoria$2BNCF 676 $a398.364 700 1$aGOUDSBLOM,$bJohan$0118153 702 1$aMERLINO,$bAnnalisa 801 0$aIT$bsalbc$gISBD 912 $a990003136510203316 951 $aII.5. 6152$b209718 L.M.$cII.5.$d00166696 959 $aBK 969 $aUMA 979 $aALESSANDRA$b90$c20080806$lUSA01$h1152 996 $aFire and civilization$925437 997 $aUNISA LEADER 02685nam 2200529 a 450 001 9910789690703321 005 20230725031535.0 010 $a1-60805-142-0 035 $a(CKB)2670000000099380 035 $a(EBL)864309 035 $a(OCoLC)779141452 035 $a(SSID)ssj0000672883 035 $a(PQKBManifestationID)11417123 035 $a(PQKBTitleCode)TC0000672883 035 $a(PQKBWorkID)10636419 035 $a(PQKB)11579601 035 $a(MiAaPQ)EBC864309 035 $a(Au-PeEL)EBL864309 035 $a(CaPaEBR)ebr10492620 035 $a(EXLCZ)992670000000099380 100 $a20110922d2011 uy 0 101 0 $aeng 135 $aurcn||||||||| 181 $ctxt 182 $cc 183 $acr 200 10$aIn silico lead discovery$b[electronic resource] /$fby Maria A. Miteva 210 $a[Saif Zone, Sharjah, United Arab Emirates] $cBentham Science Publishers Ltd.$d[2011] 215 $a1 online resource (201 p.) 300 $aDescription based upon print version of record. 311 $a1-60805-313-X 320 $aIncludes bibliographical references and index. 327 $a01 Title.pdf; 02 Cover Page; 03 eBooks End User License Agreement-Website; 04 Content; 05 Foreword_Grigirov; 06 Preface_Miteva; 07 Contributors_Proposal_forEbook-MariaMiteva; 08 Chapter 1 Lagorce_et al_revised 2; 09 Chapter 2 Sperandio_et al_revised 2; 10 Chapter 3 Guyon_Tuffery_corrected 2; 11 Chapter 4 Todorov_corrected 2; 12 Chapter 5 Alexov_revised 2; 13 Chapter 6 Miteva_revised 2; 14 Chapter 7 Roche-revised 2; 15 Chapter 8 Pajeva_Wiese_revised 2; 16 Chapter 9 Moro_revised 2; 17 Chapter 10 Lee; 18 Index 330 $aComputer-aided drug design and in silico screening have contributed to the discovery of several compounds that have either reached the market or entered clinical trials. In silico Lead Discovery is a compilation of the efforts of several experts on bioinformatics and drug design in developing the latest advances of in silico approaches for lead discovery. It contains an overview of structure-based, ligand-based methods and current fragment-based methods as well as examples for successful applications of such methods in discovering new hit/lead molecules for important therapeutic targets. Treat 606 $aDrug development 606 $aDrug development$xComputer simulation 615 0$aDrug development. 615 0$aDrug development$xComputer simulation. 676 $a615/.19 700 $aMiteva$b Maria A$01539651 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910789690703321 996 $aIn silico lead discovery$93790652 997 $aUNINA