LEADER 03363nam 2200493 450 001 9910583085103321 005 20210916153753.0 010 $a9780128144237 010 $a0128144238 010 $a9780128144244 (electronic bk.) 010 $a0128144246$b(electronic bk.) 035 $a(CKB)4100000005463973 035 $a(MiAaPQ)EBC5479170 035 $a(OCoLC)on1046633728 035 $a(PPN)243288042 035 $a(EXLCZ)994100000005463973 100 $a20180908d2018 uy 0 101 0 $aeng 135 $aurcnu|||||||| 181 $ctxt$2rdacontent 182 $cc$2rdamedia 183 $acr$2rdacarrier 200 00$aDosage form design considerations$hVolume I /$fedited by Rakesh K. Tekade 210 1$aLondon, United Kingdom :$cAcademic Press, an imprint of Elsevier,$d[2018] 210 4$dİ2018 215 $a1 online resource (881 pages) $cillustrations 225 1 $aAdvances in pharmaceutical product development and research series 327 $a1. Preformulation in Drug Research and Pharmaceutical product development 2. Physicochemical aspects to be considered in pharmaceutical product development 3. Role of physicochemical parameters on drug absorption and their implication in pharmaceutical product development 4. Physiologic factors related to drug absorption 5. Physicochemical, pharmaceutical, and biological considerations in GIT absorption of drugs 6. Influence of drug properties and routes of drug administration on the design of controlled release system 7. Stability and degradation studies for drug and drug product 8. First-pass metabolism considerations in pharmaceutical product development 9. Dissolution profile consideration in pharmaceutical product development 10. Drug disposition considerations in pharmaceutical product 11. Protein and tissue binging: implication on pharmacokinetic parameters 12. Preformulation studies of drug substances, protein, and Peptides: Role in drug discovery and pharmaceutical product development 13. Role of salt selection in drug discovery and development 14. Drug complexation: implications in drug solubilization and oral bioavailability enhancement 15. Solubility and solubilization approaches in pharmaceutical product development 16. Rheology and its implications on performance of liquid dosage forms 17. Micromeritics in pharmaceutical product development 18. Four stages of pharmaceutical product development: preformulation, prototype development and scale-up, biological aspects, and commercialization 19. Scale-up studies in pharmaceutical products development 20. Manipulation of physiological processes for pharmaceutical product development 21. Impact of pharmaceutical product quality on clinical efficacy 22. Formulation additives used in pharmaceutical products: emphasis on regulatory perspectives and GRAS 410 0$aAdvances in pharmaceutical product development and research series. 606 $aDrugs$xDesign 606 $aDrugs$xDosage forms 606 $aDrug development 615 0$aDrugs$xDesign. 615 0$aDrugs$xDosage forms. 615 0$aDrug development. 676 $a615.1900285 702 $aTekade$b Rakesh K. 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910583085103321 996 $aDosage form design considerations$92024621 997 $aUNINA LEADER 04309nam 2200793 450 001 9910788821303321 005 20210422210928.0 010 $a1-5015-0078-3 010 $a1-61451-123-3 024 7 $a10.1515/9781614511236 035 $a(CKB)3360000000514931 035 $a(EBL)1377146 035 $a(SSID)ssj0001420885 035 $a(PQKBManifestationID)11852552 035 $a(PQKBTitleCode)TC0001420885 035 $a(PQKBWorkID)11408191 035 $a(PQKB)11093133 035 $a(DE-B1597)175865 035 $a(OCoLC)951149681 035 $a(OCoLC)973399877 035 $a(DE-B1597)9781614511236 035 $a(Au-PeEL)EBL1377146 035 $a(CaPaEBR)ebr11006254 035 $a(CaONFJC)MIL805822 035 $a(OCoLC)904079357 035 $a(CaSebORM)9781501500787 035 $a(MiAaPQ)EBC1377146 035 $a(EXLCZ)993360000000514931 100 $a20150127h20142014 uy| 0 101 0 $aeng 135 $aur|nu---|u||u 181 $ctxt 182 $cc 183 $acr 200 10$aBlending spaces $emediating and assessing intercultural competence in the L2 classroom /$fArnd Witte 210 1$aBoston :$cDe Gruyter Mouton,$d[2014] 210 4$dİ2014 215 $a1 online resource (456 p.) 225 1 $aTrends in applied linguistics,$x1868-6362 ;$vvolume 8 300 $aDescription based upon print version of record. 311 0 $a1-61451-153-5 320 $aIncludes bibliographical references and index. 327 $tFront matter --$tContents --$t1 Introduction: The interplay of languages, cultures, and minds --$t2 First language acquisition and early cognitive development --$t3 Formation of concepts and plausibility structures --$t4 Language and the intersubjective construction of meaning --$t5 Imposing structure on language-in-use: From language philosophy to discourse analysis --$t6 The dynamics of identity --$t7 The complexities of culture --$t8 The interplay of cultures: Constructs of interculture --$t9 Fostering intercultural competence in the second language classroom --$t10 Mediating and assessing intercultural competence in the L2 classroom --$t11 Conclusion --$tReferences --$tName index --$tSubject index 330 $aThis book comprehensively analyzes the development of interculturally blended third spaces by the second language learner, beginning with the linguistic and sociocultural imprints of the first language and culture on the mind and culminating in the proposal of a phase-model of the development of intercultural competence. The foundational analysis of L1-mediated constructs is followed by an analysis of forms interaction, concepts of identity and constructs of culture/interculture, thus shifting the object of analysis from the subjective to the intersubjective levels of construction and interaction. The focus of the book is on the gradual development of interculturally blended third spaces in the mind of the learner as genuinely new bases for construction. This book takes an interdisciplinary approach, drawing on research in cultural psychology, linguistic anthropology, critical theory, language acquisition and second language learning and shows how culture and interculture need to be emphasized as an integral part of second language learning. 410 0$aTrends in applied linguistics ;$v8. 606 $aSecond language acquisition 606 $aIntercultural communication$xStudy and teaching 606 $aMulticultural education$xStudy and teaching 606 $aCommunicative competence$xTesting 606 $aLanguage and culture$xStudy and teaching 610 $aApplied Linguistics. 610 $aIntercultural Competence. 610 $aLanguage and Culture. 610 $aSecond Language Learning. 610 $aThird Space. 615 0$aSecond language acquisition. 615 0$aIntercultural communication$xStudy and teaching. 615 0$aMulticultural education$xStudy and teaching. 615 0$aCommunicative competence$xTesting. 615 0$aLanguage and culture$xStudy and teaching. 676 $a418.0071 700 $aWitte$b Arnd$01524226 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910788821303321 996 $aBlending spaces$93764875 997 $aUNINA