LEADER 02385nam 2200577 450 001 9910788108603321 005 20200520144314.0 035 $a(CKB)2670000000613376 035 $a(EBL)2037820 035 $a(SSID)ssj0001539558 035 $a(PQKBManifestationID)11936600 035 $a(PQKBTitleCode)TC0001539558 035 $a(PQKBWorkID)11533172 035 $a(PQKB)10116226 035 $a(Au-PeEL)EBL2037820 035 $a(CaPaEBR)ebr11051878 035 $a(CaONFJC)MIL778444 035 $a(OCoLC)908192105 035 $a(MiAaPQ)EBC2037820 035 $a(PPN)193663414 035 $a(EXLCZ)992670000000613376 100 $a20150516h20152015 uy 0 101 0 $aeng 135 $aur|n|---||||| 181 $ctxt 182 $cc 183 $acr 200 10$aPersonalized epigenetics /$fTrygve O. Tollefsbol ; designer, Mark Rogers ; contributors, Vanessa Aguiar-Pulido [and forty five others] 210 1$aAmsterdam, Netherlands :$cAcademic Press,$d2015. 210 4$dİ2015 215 $a1 online resource (611 p.) 225 0 $aTranslational Epigenetics Series 300 $aDescription based upon print version of record. 311 $a0-12-800436-3 311 $a0-12-420135-0 320 $aIncludes bibliographical references at the end of each chapters and index. 327 $a6. BRAIN CELLULAR HETEROGENEITY AND METHYLATION VARIATION 330 $a Personalized Epigenetics discusses the core translatability of epigenetics to health management of individuals who have unique variations in their epigenetic signatures that can guide both disorder and disease prevention and therapy. The book details inter-individual variability in the major epigenetic process in humans consisting of DNA methylation, histone modifications, and noncoding RNA, and the diagnostic, prognostic, and therapeutic potential of the field, it also reviews the impact of the environment on epigenetic variations among individuals and the role of pharmacology and drug de 606 $aEpigenetics 615 0$aEpigenetics. 676 $a572.865 700 $aTollefsbol$b Trygve O.$0603166 702 $aRogers$b Mark 702 $aAguiar-Pulido$b Vanessa 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910788108603321 996 $aPersonalized epigenetics$93777265 997 $aUNINA