LEADER 02889oam 2200649I 450 001 9910788023303321 005 20150413011045.0 010 $a0-429-16951-5 024 7 $a10.1201/b18274 035 $a(CKB)2670000000607466 035 $a(EBL)1591661 035 $a(SSID)ssj0001459039 035 $a(PQKBManifestationID)11822949 035 $a(PQKBTitleCode)TC0001459039 035 $a(PQKBWorkID)11456558 035 $a(PQKB)10596136 035 $a(MiAaPQ)EBC1591661 035 $a(OCoLC)906025864 035 $a(OCoLC-P)906025864 035 $a(CaSebORM)9781466597488 035 $a(EXLCZ)992670000000607466 100 $a20180331h20152015 uy 0 101 0 $aeng 135 $aur|n|---||||| 181 $ctxt 182 $cc 183 $acr 200 10$aImmune system modelling and simulation /$fFilippo Castiglione, Institute for Applied Mathematics, National Research Council of Italy, Rome, Italy and Franco Celada, Department of Medicine, Division of Rheumatology, New York University School of 210 1$aBoca Raton :$cCRC Press,$d[2015] 210 4$dİ2015 215 $a1 online resource (284 p.) 300 $a"A Science Publishers Book." 311 $a1-4665-9748-8 311 $a1-4665-9749-6 320 $aIncludes bibliographical references and index. 327 $aCover; Preface; Acknowledgments; Contents; 1: Immunology for Aliens; 2: Aliens for Immunology; 3: C-ImmSim Unveiled; 4: Benchmarks, aka Qualitative Model Validation; 5: Specific Applications; 6: One Last Word; 7: Bibliography; Colour Plate Section 330 $aImmunology for aliensLeo Szilard paradox: Grand Central TerminalNon-specific defenseLevels of evolution How is a trait selected if it was not needed?Luck or foresight?Blood brothers The members of the winning team are rewarded Somatic recombination produces diversity among equals The workshop of the adaptive response Repertoires A battalion of one Self-inflicted damage threatens survival Don't think, but reason and understandFull cover comes at a cost A bet, not a fantasy, about earliest happeningsThe cooperation of very different cells multiplies jobs that can be done Thymus deeds Hypothesis 606 $aImmunoinformatics 606 $aImmunology$xComputer simulation 606 $aResearch 606 $aComputer simulation 606 $aDigital computer simulation 615 0$aImmunoinformatics. 615 0$aImmunology$xComputer simulation. 615 0$aResearch. 615 0$aComputer simulation. 615 0$aDigital computer simulation. 676 $a616.07/90285 676 $a616.0790285 700 $aCastiglione$b Filippo$f1969,$01558821 702 $aCelada$b Franco 801 0$bFlBoTFG 801 1$bFlBoTFG 906 $aBOOK 912 $a9910788023303321 996 $aImmune system modelling and simulation$93823537 997 $aUNINA