LEADER 04008nam 2200553 450 001 9910787657903321 005 20230803031515.0 010 $a1-912530-36-8 010 $a1-908230-84-3 035 $a(CKB)2670000000427611 035 $a(EBL)1938094 035 $a(SSID)ssj0001127787 035 $a(PQKBManifestationID)11634361 035 $a(PQKBTitleCode)TC0001127787 035 $a(PQKBWorkID)11152557 035 $a(PQKB)11269059 035 $a(MiAaPQ)EBC1938094 035 $a(MiAaPQ)EBC6031537 035 $a(EXLCZ)992670000000427611 100 $a20200311d2013 uy 0 101 0 $aeng 135 $aur|n|---||||| 181 $ctxt 182 $cc 183 $acr 200 00$aCytomegaloviruses$hVolume I $efrom molecular pathogenesis to intervention /$fedited by Matthias J. Reddehase ; with the assistance of Niels A.W. Lemmermann 210 1$aNorfolk, England :$cCaister Academic Press,$d[2013] 210 4$dİ2013 215 $a1 online resource (489 p.) 300 $aDescription based upon print version of record. 311 $a1-908230-19-3 320 $aIncludes bibliographical references and indexes. 327 $aContents Volume I; Preface to the First Edition (2006); Preface; Abbreviations used in Vol I; Ch I.1: Comparative Genomics of Primate Cytomegaloviruses; Ch I.2: Molecular Evolution of Murine Cytomegalovirus Genomes; Ch I.3: Manipulating CMV Genomes by BAC Mutagenesis: Strategies and Applications; Ch I.4: Human Cytomegalovirus Metabolomics; Ch I.5: Cytomegalovirus-encoded miRNAs; Ch I.6: Cytomegalovirus Proteomics; Ch I.7: A Systems Pathway View of Cytomegalovirus Infection; Ch I.8: Virus Entry and Activation of Innate Defence; Ch I.9: Pre-Immediate Early Tegument Protein Functions 327 $aCh I.10: Major Immediate-Early Enhancer and Its Gene ProductsCh I.11: Multifaceted Regulation of Human Cytomegalovirus Gene Expression; Ch I.12: Intracellular Sorting and Trafficking of Cytomegalovirus Proteins during Permissive Infection; Ch I.13: Morphogenesis of the Cytomegalovirus Virion and Subviral Particles; Ch I.14: Exploitation of Host Cell Cycle Regulatory Pathways by HCMV; Ch I.15: Cell Death Pathways Controlled by Cytomegaloviruses; Ch I.16: Cytomegaloviruses and Interferons; Ch I.17: Cytomegalovirus Interstrain Variance in Cell Type Tropism 327 $aCh I.18: Molecular Basis of Cytomegalovirus Host Species SpecificityCh I.19: Epigenetic Regulation of Human Cytomegalovirus Gene Expression: Impact on Latency and Reactivation; Ch I.20: Transcription Associated with Human Cytomegalovirus Latency; Ch I.21: Myeloid Cell Recruitment and Function in Cytomegalovirus Dissemination and Immunity; Ch I.22: Immune Surveillance of Cytomegalovirus Latency and Reactivation in Murine Models: Link to 'Memory Inflation'; Ch I.23: Humanized Mouse Models of Cytomegalovirus Pathogenesis and Latency; Subject index; Open reading frame index 327 $aCluster of differentiation indexCMV strains index; Antiviral drugs index; Frequently discussed molecules 330 $aHuman Cytomegalovirus (CMV) - a member of the herpesvirus family - is an underrated health risk. A low public awareness results from the relatively mild symptoms it causes in otherwise healthy people whose immune systems are intact, with primary infection usually going unnoticed. During pregnancy, however, transmission from the mother to the fetus is currently the most frequent viral cause of birth defects with lifelong neurological sequelae, sensorineural hearing loss in particular. People at risk also include the growing number of immune compromised patients requiring either a solid organ gr 606 $aCytomegaloviruses 615 0$aCytomegaloviruses. 676 $a576.64 702 $aReddehase$b Matthias J. 702 $aLemmermann$b Niels 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910787657903321 996 $aCytomegaloviruses$93815216 997 $aUNINA