LEADER 02831nam 2200577 450 001 9910787592803321 005 20230803030544.0 010 $a1-78084-174-4 035 $a(CKB)2670000000391302 035 $a(EBL)1179667 035 $a(OCoLC)851970672 035 $a(SSID)ssj0001599988 035 $a(PQKBManifestationID)16306413 035 $a(PQKBTitleCode)TC0001599988 035 $a(PQKBWorkID)14892859 035 $a(PQKB)11460261 035 $a(MiAaPQ)EBC1179667 035 $a(Au-PeEL)EBL1179667 035 $a(EXLCZ)992670000000391302 100 $a20220517d2013 uy 0 101 0 $aeng 135 $aur|n|---||||| 181 $ctxt 182 $cc 183 $acr 200 00$aPolycystic kidney disease $efrom bench to bedside /$feditors, Vincent H. Gattone, Robert L. Bacall 205 $a1st ed. 210 1$aLondon, England :$cFuture Medicine Ltd.,$d[2013] 210 4$dİ2013 215 $a1 online resource (195 p.) 300 $aDescription based upon print version of record. 311 $a1-78084-176-0 327 $aTitle page; Copyright page; Contents; Foreword. Polycystic kidney disease: from bench to bedside; 1. Polycystic kidney disease: genes, prevalence and diagnosis; 2. Polycystins and the pathophysiology of autosomal dominant polycystic kidney disease; 3. Fibrocystin/polyductin and pathophysiology of autosomal recessive polycystic kidney disease; 4. Nephronophthisis; 5. Meckel syndrome; 6. The Bardet-Biedl and orofacial digital type I ciliopathies; 7. Pain and pain management in polycystic kidney disease; 8. Hypertension in autosomal dominant polycystic kidney disease 327 $a9. Complications of polycystic kidney disease10. End-stage renal disease in polycystic kidney disease; 11. Preclinical and clinical trials for identifying treatments for polycystic kidney disease; Index 330 $aRecent years have seen advances in our understanding the molecular cell biology, signaling and pathogenesis of one of the most common life-threatening genetic diseases - polycystic kidney disease (PKD). This multichapter work from international experts opens with chapters exploring the pathogenesis and pathophysiology of autosomal dominant and autosomal recessive PKD. 606 $aPolycystic kidney disease 606 $aPolycystic kidney disease$xDiagnosis 606 $aPolycystic kidney disease$xTreatment 615 0$aPolycystic kidney disease. 615 0$aPolycystic kidney disease$xDiagnosis. 615 0$aPolycystic kidney disease$xTreatment. 676 $a616.61042 702 $aGattone$b Vincent H. 702 $aBacall$b Robert L. 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910787592803321 996 $aPolycystic kidney disease$92859144 997 $aUNINA