LEADER 02463nam 2200565 a 450 001 9910787564603321 005 20200520144314.0 010 $a1-118-67079-5 010 $a1-118-67076-0 010 $a1-118-67078-7 035 $a(CKB)2670000000400575 035 $a(EBL)1315451 035 $a(OCoLC)853364577 035 $a(OCoLC)841199233 035 $a(MiAaPQ)EBC1315451 035 $a(DLC) 2013016647 035 $a(Au-PeEL)EBL1315451 035 $a(CaPaEBR)ebr10734633 035 $a(CaONFJC)MIL505106 035 $a(MiAaPQ)EBC7147319 035 $a(Au-PeEL)EBL7147319 035 $a(PPN)192309080 035 $a(EXLCZ)992670000000400575 100 $a20130805d2013 uy 0 101 0 $aeng 135 $aur|n|---||||| 181 $ctxt$2rdacontent 182 $cc$2rdamedia 183 $acr$2rdacarrier 200 10$aBiostatistics decoded$b[electronic resource]$fA. Gouveia Oliveira 205 $a1st ed. 210 $aChichester, England $cWiley$dc2013 215 $a1 online resource (347 p.) 300 $aDescription based upon print version of record. 311 $a1-299-73855-9 311 $a1-119-95337-5 320 $aIncludes bibliographical references and index. 327 $aBasic concepts -- Statistical inference -- Descriptive studies -- Analytical studies -- Statistical tests -- Issues with statistical tests -- Longitudinal studies -- Statistical modelling -- Measurement -- Experimental studies -- The analysis of experimental studies -- Meta-analysis of clinical trials. 330 $a Study design and statistical methodology are two important concerns for the clinical researcher. This book sets out to address both issues in a clear and concise manner. The presentation of statistical theory starts from basic concepts, such as the properties of means and variances, the properties of the Normal distribution and the Central Limit Theorem and leads to more advanced topics such as maximum likelihood estimation, inverse variance and stepwise regression as well as, time-to-event, and event-count methods. Furthermore, this book explores sampling methods, study design and statisti 606 $aBiometry 615 0$aBiometry. 676 $a610.72/7 700 $aOliveira$b A. Gouveia de$01571987 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910787564603321 996 $aBiostatistics decoded$93846569 997 $aUNINA