LEADER 05462nam 2200649 450 001 9910787503203321 005 20230803194952.0 010 $a1-4619-4819-3 010 $a1-61705-105-5 035 $a(CKB)2670000000428189 035 $a(EBL)1481032 035 $a(SSID)ssj0001035812 035 $a(PQKBManifestationID)12461498 035 $a(PQKBTitleCode)TC0001035812 035 $a(PQKBWorkID)11032947 035 $a(PQKB)11235245 035 $a(Au-PeEL)EBL1481032 035 $a(CaPaEBR)ebr10769586 035 $a(CaONFJC)MIL539926 035 $a(OCoLC)861559295 035 $a(MiAaPQ)EBC1481032 035 $a(EXLCZ)992670000000428189 100 $a20130524h20142014 uy 0 101 0 $aeng 135 $aur|n|---||||| 181 $ctxt 182 $cc 183 $acr 200 00$aCancers of the colon and rectum $ea multidisciplinary approach to diagnosis and management /$fedited by Al B. Benson [and three others] 210 1$aNew York :$cDemos Medical Publishing,$d[2014] 210 4$dİ2014 215 $a1 online resource (347 p.) 225 0$aCurrent multidisciplinary oncology 300 $aDescription based upon print version of record. 311 $a1-936287-58-7 320 $aIncludes bibliographical references and index. 327 $aCover; Title page; Copyright; Contents; Series Foreword; Preface; Contributors; 1. Importance of the Multidisciplinary Approach to Colorectal Cancer; 2. Prevention and Screening; Risk Factors, Screening, and Chemoprevention; Epidemiology; The Biology of CRC; Screening for CRC; Screening Recommendations; Chemoprevention in CRC; Clinical Evaluations to Date; The Future of CRC; Identification of High-Risk Patients: Familial and Environmental Factors; Family History of CRC Outside of Known Genetic Syndromes; Risk Conferred by Personal History of Noncolorectal Cancer; Risk Related to Ethnicity 327 $aHereditary Syndromes of CRCLynch Syndrome as a Model for Identification of Hereditary High-Risk Patients; Introduction; Family Considerations; LS Characteristics; Cancer Spectrum in LS; Management; Future Research Developments; Summary; Colorectal Cancer in Inf Lammatory Bowel Disease; Risk Factors for CRC in Chronic Colitis; Dysplasia as a Precursor for Cancer in IBD; Management of Dysplasia in Flat Mucosa; Management of Raised Dysplastic Lesions; References; 3. Navigation Programs in Colorectal Cancer Care; Rationale for Colorectal Navigation Services 327 $aOverview of the Role of Navigation as it Supports Multidisciplinary Care ModelsOverview of the Program; Nurse Navigator Placement-Location, Location, Location!; Navigation Role in Colorectal Quality Care; References; 4. Assessment and Management of Colorectal Polyps and Cancer Precursor Lesions; Introduction; Molecular Pathogenesis of CRC; Precancerous Colorectal Neoplasms; Screening for Polyps and Precursor Lesions; Polyp and Precursor Lesion Detection and Removal; References; 5. Preoperative Staging: Imaging and Endoscopic Approaches; Multimodality Imaging of Colorectal Cancer; Screening 327 $aLocal StagingEvaluation of Metastatic Disease; Endoscopic Approaches to Colon Cancer; Diagnostic Considerations for Colon Cancer: Colonoscopy; Endoscopic Management of Malignant Colon Polyps and Polyps with High Grade Dysplasia; Endoscopic Approaches to Rectal Cancer; References; 6. Pathology and Molecular Diagnostics; Pathology of Colon and Rectal Carcinoma; Pathology of Precursor Lesions and Conditions; Molecular Pathology of Colon and Rectal Carcinoma; Clinical-Pathologic Correlations with Molecular Pathways; Conclusions; References; 7. Management of Nonmetastatic Colon Cancer 327 $aSurgical ConsiderationsHistory of Surgery for Colon Cancer; Epidemiology of Colon Cancer; The Role of Chemotherapy; Introduction; Decrease in Mortality with Adjuvant Chemotherapy; Unrealized Promise: Failure in the Adjuvant Setting of Other Agents Approved for Stage IV Disease; Current Open Questions and Areas of Debate in Adjuvant Colon Cancer; How Much is Enough? the Idea Effort and Evidence for Shorter Duration of Chemotherapy; Personalized Medicine-Unrealized Promises in adjuvant Colon Cancer; Markers That are Not prognostic: K-Ras, Mss, and Loh at 18Q; Elderly Patients; Conclusions 327 $aReferences 330 $aOver the course of the last decade, the treatment of colorectal cancer has evolved quite rapidly. New scientific and clinical advances have modified the standard of care and led to improved patient outcomes. At the same time, the treatment of colorectal cancer has become increasingly complex, requiring the comprehensive review and assessment of multiple issues including genetics, radiology, surgery, molecular diagnostics, chemotherapy, and more. As a result the harmony and open communication between these specialties facilitated by a multidisciplinary team approach are crucial in providing the 410 0$aCurrent Multidisciplinary Oncology 606 $aColon (Anatomy)$xCancer$xDiagnosis 606 $aColon (Anatomy)$xCancer$xTreatment 615 0$aColon (Anatomy)$xCancer$xDiagnosis. 615 0$aColon (Anatomy)$xCancer$xTreatment. 676 $a616.99/4347 701 $aBenson$b Al B.$cIII.$01164883 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910787503203321 996 $aCancers of the colon and rectum$93773017 997 $aUNINA