LEADER 02781nam 2200601 450 001 9910787375803321 005 20230120002206.0 010 $a0-12-405176-6 035 $a(CKB)3710000000341468 035 $a(OCoLC)900781265 035 $a(CaPaEBR)ebrary11011293 035 $a(SSID)ssj0001433100 035 $a(PQKBManifestationID)11995088 035 $a(PQKBTitleCode)TC0001433100 035 $a(PQKBWorkID)11413383 035 $a(PQKB)11744611 035 $a(MiAaPQ)EBC1929994 035 $a(Au-PeEL)EBL1929994 035 $a(CaPaEBR)ebr11011293 035 $a(CaONFJC)MIL708926 035 $a(EXLCZ)993710000000341468 100 $a20150205h20152015 uy 0 101 0 $aeng 135 $aurcnu|||||||| 181 $ctxt 182 $cc 183 $acr 200 00$aClinical trial design challenges in mood disorders /$fedited by Mauricio Tohen [and three others] 210 1$aLondon, England :$cAcademic Press,$d2015. 210 4$dİ2015 215 $a1 online resource (192 p.) 300 $aBibliographic Level Mode of Issuance: Monograph 311 $a1-322-77644-X 311 $a0-12-405170-7 320 $aIncludes bibliographical references at the end of each chapters and index. 327 $aClinical trial design and maintenance treatments in bipolar disorder -- Meta-analysis of clinical trials in bipolar disorder -- Effectiveness trials in bipolar disorders -- Long-term treatment of mood disorders : follow-up of acute treatment phases studies versus continuation and maintenance phase studies, and enriched versus non-enriched designs -- The role of noninferiority designs in bipolar disorder clinical trials -- The use of mixed methods in drug discovery : integrating qualitative methods into clinical trials -- Sequential multiple assignment randomized treatment (SMART) : designs in bipolar disorder clinical trials -- Novel study designs for clinical trials in mood disorders -- Rating scales in bipolar disorder -- Clinical applicability of results from drug trials in bipolar disorder -- an attempt to shed light on a complex issue -- Clinical trials in developing countries : challenges in design, execution, and regulation. 606 $aAffective disorders 606 $aBipolar Disorder$xtherapy 606 $aMood Disorders$xtherapy 606 $aClinical Trials as Topic 615 0$aAffective disorders. 615 12$aBipolar Disorder$xtherapy. 615 22$aMood Disorders$xtherapy. 615 22$aClinical Trials as Topic. 676 $a616.8527 702 $aTohen$b Mauricio 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910787375803321 996 $aClinical trial design challenges in mood disorders$93746998 997 $aUNINA LEADER 01389aam 2200409I 450 001 9910711234803321 005 20251201184252.0 024 8 $aGOVPUB-C13-816b79e8768a4e9482477811affc795f 035 $a(CKB)5470000002481675 035 $a(OCoLC)929064693 035 $a(EXLCZ)995470000002481675 100 $a20151113d1976 ua 0 101 0 $aeng 181 $2rdacontent 182 $2rdamedia 183 $2rdacarrier 200 10$aEvaluation, revision and application of the NBS stylus /$fE. C. Teague 210 1$aGaithersburg, MD :$cU.S. Dept. of Commerce, National Institute of Standards and Technology,$d1976. 215 $a1 online resource 225 1 $aNBS technical note ;$v902 300 $a1976. 300 $aContributed record: Metadata reviewed, not verified. Some fields updated by batch processes. 300 $aTitle from PDF title page. 320 $aIncludes bibliographical references. 606 $aMinicomputers$xProgramming 606 $aSurfaces 615 0$aMinicomputers$xProgramming. 615 0$aSurfaces. 700 $aTeague$b E. C$g(Edgar Clayton),$f1941-$01399064 712 02$aUnited States.$bNational Bureau of Standards. 801 0$bNBS 801 1$bNBS 801 2$bGPO 906 $aBOOK 912 $a9910711234803321 996 $aEvaluation, revision and application of the NBS stylus$93463690 997 $aUNINA