LEADER 03514oam 2200649I 450 001 9910787342203321 005 20231101191057.0 010 $a0-429-17333-4 010 $a1-4987-1138-3 024 7 $a10.1201/b18111 035 $a(CKB)3710000000357817 035 $a(EBL)1758189 035 $a(SSID)ssj0001470742 035 $a(PQKBManifestationID)11865550 035 $a(PQKBTitleCode)TC0001470742 035 $a(PQKBWorkID)11433556 035 $a(PQKB)10352462 035 $a(MiAaPQ)EBC1758189 035 $a(OCoLC)899709578 035 $a(EXLCZ)993710000000357817 100 $a20180331h20152015 uy 0 101 0 $aeng 135 $aur|n|---||||| 181 $ctxt$2rdacontent 182 $cc$2rdamedia 183 $acr$2rdacarrier 200 10$aMuscular and skeletal anomalies in human trisomy in an evo-devo context $edescription of a T18 cyclopic fetus and comparison between Edwards (T18), Patau (T13) and Down (T21) syndromes using 3-D imaging and anatomical illustrations /$fChristopher M. Smith [et al.], editors 210 1$aBoca Raton :$cCRC Press :$cTaylor & Francis Group,$d[2015] 210 4$dİ2015 215 $a1 online resource (x, 212 pages) $cillustrations (some color) 300 $aA Science publishers book. 311 0 $a1-322-99937-6 311 0 $a1-4987-1137-5 320 $aIncludes bibliographical references. 327 $aFront Cover; Preface; Acknowledgements; Contents; Chapter 1 - Topics and Purpose of this Book; Chapter 2 - The Musculoskeletal System of a 28-week Human Trisomy 18 Cyclopia Fetus; Chapter 3 - Comparative Anatomy of Muscular Anomalies in Trisomies 13, 18, and 21; Chapter 4 - Cyclopia, Trisomic Anomalies, and Order versus Chaos in Development and Evolution; Chapter 5 - Digits and Muscles: Topology-Directed Muscle Attachment; Chapter 6 - Evolutionary Mechanisms and Mouse Models for Down Syndrome; Illustrations; References; Appendix A - Dissection Photographs of Trisomy 18 Human Cyclopia Fetus; Appendix B - 3-D Renders of Trisomy 18 Human Cyclopia Fetus CT Scan Data; About the Authors; Color Plate Section; Back Cover 330 $aThis book focuses on human anatomy and medicine and specifically on both muscular and skeletal birth defects in humans with trisomy. Moreover, this book also deals with Down syndrome, which is one of the most studied human syndromes and, due to its high incidence and the fact that individuals with this syndrome often live until adulthood, is of special interest to the scientific and medical community. This new line of inquiry is addressed to a wide audience, including medical researchers, physicians, surgeons, medical and dental students, pathologists, and pediatricians, among others 606 $aAbnormalities, Human$xGenetic aspects 606 $aHuman chromosome abnormalities 606 $aHuman anatomy 615 0$aAbnormalities, Human$xGenetic aspects. 615 0$aHuman chromosome abnormalities. 615 0$aHuman anatomy. 676 $a618.920042 702 $aSmith$b Christopher M 702 $aZiermann$b Janine M.$f1980- 702 $aSandone$b Corinne 702 $aBersu$b Edward T.$f1946- 702 $aMolnar$b Julia L. 702 $aGondre-Lewis$b Marjorie C. 702 $aAziz$b Ashraf 702 $aDiogo$b Rui 801 0$bFlBoTFG 801 1$bFlBoTFG 906 $aBOOK 912 $a9910787342203321 996 $aMuscular and skeletal anomalies in human trisomy in an evo-devo context$93726459 997 $aUNINA