LEADER 03677oam 2200661I 450 001 9910787333703321 005 20230803194837.0 010 $a0-429-09493-0 010 $a981-4411-60-4 024 7 $a10.1201/b15667 035 $a(CKB)2670000000394376 035 $a(EBL)1408057 035 $a(SSID)ssj0001034605 035 $a(PQKBManifestationID)11620428 035 $a(PQKBTitleCode)TC0001034605 035 $a(PQKBWorkID)11017308 035 $a(PQKB)10797125 035 $a(OCoLC)874179793 035 $a(MiAaPQ)EBC1408057 035 $a(OCoLC)870909189 035 $a(EXLCZ)992670000000394376 100 $a20180331h20142014 uy 0 101 0 $aeng 135 $aur|n|---||||| 181 $ctxt$2rdacontent 182 $cc$2rdamedia 183 $acr$2rdacarrier 200 00$aBiofunctional surface engineering /$fedited by Martin Scholz 210 1$aBoca Raton :$cPan Stanford Publishing,$d[2014] 210 4$d©2014 215 $a1 online resource (339 p.) 300 $aDescription based upon print version of record. 311 $a981-4411-61-2 320 $aIncludes bibliographical references at the end of each chapters. 327 $aFront Cover; Dedication; Contents; Preface; Acknowledgment; Chapter 1 - Regulatory Requirements for Medical Devices, Including Combinations with Biological Products or Drugs as an Integral Part; Chapter 2 - Terminal Radiation Sterilization of Combination Products; Chapter 3 - Polyelectrolyte Multilayers as Functional Coatings for Controlled Biomolecular Interactions; Chapter 4 - Polyelectrolyte Multilayers as Functional Coatings for Controlled Biomolecular Interactions; Chapter 5 - Surface Characteristics and Biofilms; Chapter 6 - Antimicrobial Implant Coating 327 $aChapter 7 - Small-Angle X-Ray Spectroscopy as a Method to Monitor the Three-Dimensional Structure of Immobilized Biomolecules on Medical Device Scaffolds during ProductionChapter 8 - Aptamers as Biomimetic Surface Coatings for Blood-Contacting Implants; Chapter 9 - Microneedles and Nanopatches for Transdermal Vaccination; Chapter 10 - Autoantibodies as Biomarkers for Disease Diagnosis; Chapter 11 - Biofunctionalized Wound Dressings for Advanced Wound Care; Chapter 12 - Circulating Tumor Cell: Trapping Devices 327 $aChapter 13 - Evidence Generation for Medical Devices: The Case of Cemented Joint Replacement Surgery in Arthroplasty RegistriesBack Cover 330 $aSuccessful biofunctional surface engineering will determine the future of medical devices such as orthopedic implants, stents, catheters, vaccine scaffolds, wound dressings, and extracorporeal circulation devices. Moreover, the biosensor and diagnostic chip technology will evolve rapidly due to the growing medical need for personalized medicine. A major drawback in these technologies is the need for terminally sterilized products. However, novel and safe technologies, including coupling, stabilization, and protection of effector molecules, enable terminal sterilization without functional lo 606 $aBioengineering 606 $aBiomedical engineering 606 $aBiomedical materials 606 $aBiologicals 606 $aSterilization 606 $aCoatings 615 0$aBioengineering. 615 0$aBiomedical engineering. 615 0$aBiomedical materials. 615 0$aBiologicals. 615 0$aSterilization. 615 0$aCoatings. 676 $a620.00420157419 702 $aScholz$b Martin$f1960- 801 0$bFlBoTFG 801 1$bFlBoTFG 906 $aBOOK 912 $a9910787333703321 996 $aBiofunctional surface engineering$93868770 997 $aUNINA LEADER 03905nam 22007335 450 001 9910495162603321 005 20260317162740.0 010 $a981-336-191-3 024 7 $a10.1007/978-981-33-6191-1 035 $a(CKB)4100000011994704 035 $a(MiAaPQ)EBC6689022 035 $a(Au-PeEL)EBL6689022 035 $a(PPN)260306460 035 $a(OCoLC)1262726517 035 $a(DE-He213)978-981-33-6191-1 035 $a(EXLCZ)994100000011994704 100 $a20210731d2021 u| 0 101 0 $aeng 135 $aurcnu|||||||| 181 $ctxt$2rdacontent 182 $cc$2rdamedia 183 $acr$2rdacarrier 200 10$aAdvances in Bioinformatics /$fedited by Vijai Singh, Ajay Kumar 205 $a1st ed. 2021. 210 1$aSingapore :$cSpringer Nature Singapore :$cImprint: Springer,$d2021. 215 $a1 online resource (446 pages) 225 1 $aComputer Science Series 311 08$a981-336-190-5 327 $a1 An Introduction to Bioinformatics -- 2 Bioinformatics tools and softwares -- 3 Role of Bioinformatics in Biological Sciences -- 4 Protein Analysis: from Sequence to Structure -- 5 Computational Evolutionary Biology -- 6 Web-based Bioinformatics Approach Towards Analysis of Regulatory Sequences -- 7 Bioinformatics for SNPs Analysis -- 8 Vaccine Design and Immunoinformatics -- 9 Advances in Structural Bioinformatics -- 10 Computer Added Drug Designing -- 11 Chemoinformatics and QSAR -- 12 Computational Genomics -- 13 A guide to RNA-seq Data Analysis using Bioinformatics Approaches -- 14 Computational Proteomics -- 15 Computational Metabolomics -- 16 Next Generation Sequencing -- 17 Bioinformatics in Personalized Medicine -- 18 Gene and Genome Annotation and Analysis -- 19 Bioinformatics for Human Microbiome -- 20 Neural Network Analysis -- 21 Role of Bioinformatics in MicroRNA Analysis -- 22 Bioinformatics for Image Processing -- 23 Big Data Analysis in Bioinformatics -- 24 Soft Computing in Bioinformatics.-25 Artificial Intelligence in Bioinformatics. . 330 $aThis book presents the latest developments in bioinformatics, highlighting the importance of bioinformatics in genomics, transcriptomics, metabolism and cheminformatics analysis, as well as in drug discovery and development. It covers tools, data mining and analysis, protein analysis, computational vaccine, and drug design. Covering cheminformatics, computational evolutionary biology and the role of next-generation sequencing and neural network analysis, it also discusses the use of bioinformatics tools in the development of precision medicine. This book offers a valuable source of information for not only beginners in bioinformatics, but also for students, researchers, scientists, clinicians, practitioners, policymakers, and stakeholders who are interested in harnessing the potential of bioinformatics in many areas. . 410 0$aComputer Science Series 606 $aBioinformatics 606 $aProteins 606 $aGenomics 606 $aCheminformatics 606 $aArtificial intelligence 606 $aBioinformatics 606 $aProteins 606 $aGenomics 606 $aCheminformatics 606 $aArtificial Intelligence 606 $aBioinformàtica$2thub 608 $aLlibres electrònics$2thub 615 0$aBioinformatics. 615 0$aProteins. 615 0$aGenomics. 615 0$aCheminformatics. 615 0$aArtificial intelligence. 615 14$aBioinformatics. 615 24$aProteins. 615 24$aGenomics. 615 24$aCheminformatics. 615 24$aArtificial Intelligence. 615 7$aBioinformàtica 676 $a570.285 702 $aSingh$b Vijai 702 $aKumar$b Ajay 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910495162603321 996 $aAdvances in bioinformatics$92112776 997 $aUNINA