LEADER 03225oam 2200613I 450 001 9910786836103321 005 20170821193846.0 010 $a0-429-07396-8 010 $a1-4665-9271-0 024 7 $a10.1201/b16839 035 $a(CKB)3710000000108098 035 $a(EBL)1550642 035 $a(SSID)ssj0001197071 035 $a(PQKBManifestationID)11731055 035 $a(PQKBTitleCode)TC0001197071 035 $a(PQKBWorkID)11176671 035 $a(PQKB)11138200 035 $a(OCoLC)879550869 035 $a(MiAaPQ)EBC1550642 035 $a(OCoLC)1350746522 035 $a(OCoLC-P)1350746522 035 $a(CaSebORM)9781466592698 035 $a(EXLCZ)993710000000108098 100 $a20180331h20142014 uy 0 101 0 $aeng 135 $aur|n|---||||| 181 $ctxt 182 $cc 183 $acr 200 10$aSynthetic gene network $emodeling, analysis, and robust design methods /$fBor-Sen Chen, Laboratory of Control and Systems Biology, Department of Electrical Engineering, National Tsing Hua University, Hsinchu, Taiwan and Yu-Chao Wang, Institute 205 $a[First edition]. 210 1$aBoca Raton :$cCRC Press/Taylor & Francis Group,$d[2014] 210 4$dİ2014 215 $a1 online resource (216 p.) 300 $aDescription based upon print version of record. 311 $a1-306-86807-6 311 $a1-4665-9269-9 320 $aIncludes bibliographical references and index. 327 $aFront Cover; Preface; Contents; Chapter 1: General Introduction; Chapter 2: Mathematical Models and Design Specifications in Synthetic Gene Networks; Chapter 3: Robust Synthetic Biology Designs based on System Dynamic Models; Chapter 4: Robust Synthetic Biology Designs based on Network Evolutionary Methods; Chapter 5: Construction of Promoter and Promoter-RBS Libraries for Synthesis of Gene Networks; Chapter 6: Robust Synthetic Gene Network Designs based on Library-search Method; Chapter 7: Robust Design of Synthetic Biological Filter and Transistor based on Promoter-RBS Libraries 327 $aChapter 8: Communication and Synchronization of a Population of Coupled Synthetic Gene NetworksColor Plate Section; Back Cover 330 $aThis book develops a rational design and systematic approach to construct a gene network with desired behaviors. In order to achieve this goal, the registry of standard biological parts and experimental techniques are introduced at first. Then these biological components are characterized by a standard modeling method and collected in the component libraries, which can be efficiently reused in engineering synthetic gene networks. Based on the system theory, some design specifications are provided to engineer the synthetic gene networks to robustly track the desired trajectory by employing t 606 $aGene regulatory networks 606 $aGenetic engineering 615 0$aGene regulatory networks. 615 0$aGenetic engineering. 676 $a576.5 700 $aChen$b Bor-Sen$0943906 702 $aWang$b Yu-Chao$f1981- 801 0$bFlBoTFG 801 1$bFlBoTFG 906 $aBOOK 912 $a9910786836103321 996 $aSynthetic gene network$93682197 997 $aUNINA