LEADER 03107oam 2200601I 450 001 9910786834803321 005 20170821193839.0 010 $a1-77463-334-5 010 $a0-429-15995-1 010 $a1-4822-4355-5 024 7 $a10.1201/b16844 035 $a(CKB)3710000000108108 035 $a(EBL)1570073 035 $a(SSID)ssj0001215633 035 $a(PQKBManifestationID)11738166 035 $a(PQKBTitleCode)TC0001215633 035 $a(PQKBWorkID)11177822 035 $a(PQKB)10981606 035 $a(OCoLC)880455960 035 $a(MiAaPQ)EBC1570073 035 $a(OCoLC)879550964 035 $a(EXLCZ)993710000000108108 100 $a20180331h20142014 uy 0 101 0 $aeng 135 $aur|n|---||||| 181 $ctxt 182 $cc 183 $acr 200 00$aComparative immunoglobulin genetics /$fedited by Azad K. Kaushik, DVM, DSc (Paris), and Yfke Pasman, PharmD, MSc, University of Guelph, Guelph, Ontario Canada 205 $aFirst edition. 210 1$aWaretown, N.J. :$cApple Academic Press, Inc.,$d[2014] 210 4$dİ2014 215 $a1 online resource (258 p.) 300 $aDescription based upon print version of record. 311 $a1-306-86637-5 311 $a1-77188-014-7 320 $aIncludes bibliographical references. 327 $aFront Cover; About The Editors; Contents; List Of Contributors; List Of Abbreviations; Preface; Chapter 1 Variable Lymphocyte Receptor-based Adaptive Immunity In The Agnathan Sea Lamprey; Chapter 2 Agnathan Sea Lamprey Tetrapods; Chapter 3 The Immunoglobulin Genes Of Bats; Chapter 4 Marsupial And Monotreme Immunoglobulin Genetics; Chapter 5 Organization Of The Immunoglobulin Heavy- And Light-chain Loci In The Rat; Chapter 6 Generation Of The Antibody Repertoire In Rabbits: Role Of Gut-associated Lymphoid Tissues; Chapter 7 The Immunoglobulin Genes Of Domestic Swine 327 $aChapter 8 Bovine Immunoglobulin Genetics: Novel Phylogenetic PerspectiveChapter 9 Informatic Tools For Immunoglobulin Gene Sequence Analysis; Back Cover 330 $aThis contemporary book covers significant new knowledge that has emerged during the last two decades and, thus, provides novel antibody phylogenetic perspectives relevant to development of new antibody-based therapeutics and vaccines. It fills a much-needed niche in the area of immunoglobulin genetics across species from a comparative perspective. New insights and perspectives from immunoglobulin genetics from species such as sea lamprey, cattle, marsupial, bat, rat, rabbit, and swine-other species than the traditional subjects of mice and humans-are relevant to antibody design and engineer 606 $aImmunoglobulins$xGenetics 606 $aImmunoglobulin genes$vCongresses 615 0$aImmunoglobulins$xGenetics. 615 0$aImmunoglobulin genes 676 $a616.07/98 702 $aKaushik$b Azad K. 702 $aPasman$b Yfke 801 0$bFlBoTFG 801 1$bFlBoTFG 906 $aBOOK 912 $a9910786834803321 996 $aComparative immunoglobulin genetics$93682184 997 $aUNINA