LEADER 04024oam 2200649I 450 001 9910786225803321 005 20230803025716.0 010 $a0-429-10692-0 010 $a1-4398-5527-7 024 7 $a10.1201/b14569 035 $a(CKB)2670000000342220 035 $a(EBL)1165868 035 $a(OCoLC)839863005 035 $a(SSID)ssj0000855864 035 $a(PQKBManifestationID)12458827 035 $a(PQKBTitleCode)TC0000855864 035 $a(PQKBWorkID)10807592 035 $a(PQKB)11234251 035 $a(MiAaPQ)EBC1165868 035 $a(Au-PeEL)EBL1165868 035 $a(CaPaEBR)ebr10684450 035 $a(CaONFJC)MIL502249 035 $a(EXLCZ)992670000000342220 100 $a20180331d2013 uy 0 101 0 $aeng 135 $aur|n|---||||| 181 $ctxt 182 $cc 183 $acr 200 00$aCarotenoids and vitamin A in translational medicine /$fedited by Olaf Sommerburg, Werner Siems, and Klaus Kraemer 210 1$aBoca Raton, Fla :$cCRC Press/Taylor & Francis Group,$d2013. 215 $a1 online resource (431 p.) 225 1 $aOxidative stress and disease 300 $aDescription based upon print version of record. 311 $a1-138-19947-8 311 $a1-4398-5526-9 320 $aIncludes bibliographical references. 327 $aFront Cover; Contents; Preface; Series Preface; Editors; Contributors; Chapter 1 - Hepatic Retinoid Metabolism: What Is Known and What Is Not; Chapter 2 - Metabolism of Vitamin A in White Adipose Tissue and Obesity; Chapter 3 - Retinoids in the Treatment of Psoriasis; Chapter 4 - Age-Related Macular Degeneration and Carotenoids; Chapter 5 - Lutein, Zeaxanthin, and Vision across the Life Span; Chapter 6 - Assuring Vitamin A Adequacy to Prevent Eye and Ear Disorders; Chapter 7 - Disturbed Accumulation and Abnormal Distribution of Macular Pigment in Retinal Disorders 327 $aChapter 8 - Retinol and Otitis MediaChapter 9 - Carotenoids and Mutagenesis; Chapter 10 - Carotenoids and Vitamin A in Lung Cancer Prevention; Chapter 11 - Is the Effect of ?-Carotene on Prostate Cancer Cells Dependent on Their Androgen Sensitivity?; Chapter 12 - Carotenoid Intake and Supplementation in Cancer: Pro and Con; Chapter 13 - Vitamin A in Lung Development and Function; Chapter 14 - Vitamin A and Carotenoids in Lung Diseases; Chapter 15 - Chemopreventive Effects of Astaxanthin on Inflammatory Bowel Disease and Inflammation-Related Colon Carcinogenesis 327 $aChapter 16 - Carotenoids in Laboratory MedicineChapter 17 - Supply of Vitamin A in Developing Countries; Chapter 18 - Vitamin A Intakes Are Below Recommendations in a Significant Proportion of the Population in the Western World; Chapter 19 - Critical Appraisal of Vitamin A Supplementation Program in India; Chapter 20 - Consequences of Common Genetic Variations on ?-Carotene Cleavage for Vitamin A Supply; Back Cover 330 $aVitamin A (retinol) is an essential dietary compound with myriad metabolic and regulatory functions. Deficiency can result in vision problems, compromised immune responses, and a host of other medical issues. More than 600 carotenoids have been identified in plants, algae, fungi, and bacteria, and around 50 carotenoids-including ß-carotene-can be converted into vitamin A. 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