LEADER 03652oam 2200625I 450 001 9910781746803321 005 20230725051239.0 010 $a0-429-13666-8 010 $a1-283-27446-9 010 $a9786613274465 010 $a1-4398-1994-7 024 7 $a10.1201/b10714 035 $a(CKB)2550000000048814 035 $a(EBL)773634 035 $a(OCoLC)754582408 035 $a(SSID)ssj0000517107 035 $a(PQKBManifestationID)11318529 035 $a(PQKBTitleCode)TC0000517107 035 $a(PQKBWorkID)10478681 035 $a(PQKB)11377437 035 $a(MiAaPQ)EBC773634 035 $a(Au-PeEL)EBL773634 035 $a(CaPaEBR)ebr10495986 035 $a(CaONFJC)MIL327446 035 $a(EXLCZ)992550000000048814 100 $a20180331d2011 uy 0 101 0 $aeng 135 $aur|n|---||||| 181 $ctxt 182 $cc 183 $acr 200 00$aHandbook of analysis of oligonucleotides and related products /$fedited by Jose V. Bonilla, G. Susan Srivatsa 210 1$aBoca Raton, Fla. :$cCRC Press,$d2011. 215 $a1 online resource (502 p.) 300 $aDescription based upon print version of record. 311 $a1-4398-1993-9 320 $aIncludes bibliographical references and index. 327 $aFront Cover; Contents; Preface; Editors; Contributors; Introduction; Chapter 1: Purity Analysis and Impurities Determination by Reversed-Phase High-Performance Liquid Chromatography; Chapter 2: Purity Analysis and Impurities Determination by AEX-HPLC; Chapter 3: Purity Analysis and Molecular Weight Determination by Size Exclusion HPLC; Chapter 4: Analysis of Oligonucleotides by Liquid Chromatography and Mass Spectrometry; Chapter 6: Tm Analysis of Oligonucleotides; Chapter 7: Purity and Content Analysis of Oligonucleotides by Capillary Gel Electrophoresis 327 $aChapter 8: Bioanalysis of Therapeutic Oligonucleotides Using Hybridization-Based Immunoassay TechniquesChapter 9: Oligonucleotide Assay and Potency; Chapter 10: Microbial Analysis : Endotoxin Testing; Chapter 11: Analysis of Residual Solvents by Head Space Gas Chromatography; Chapter 12: Determination of Extinction Coefficient; Chapter 13: Structural Determination by NMR; Chapter 14: Infrared Analysis of Oligonucleotides; Chapter 15: Stability Indicating Methods for Oligonucleotide Products; Chapter 16: Analysis by Hydrophilic Interaction Chromatography 327 $aChapter 17: Determination of Base CompositionChapter 19: Regulatory Considerations for the Development of Oligonucleotide Therapeutics; Back Cover 330 $aOligonucleotides represent one of the most significant pharmaceutical breakthroughs in recent years, showing great promise as diagnostic and therapeutic agents for malignant tumors, cardiovascular disease, diabetes, viral infections, and many other degenerative disorders. The Handbook of Analysis of Oligonucleotides and Related Products is an essential reference manual on the practical application of modern and emerging analytical techniques for the analysis of this unique class of compounds. A strong collaboration among thirty leading analytical scientists from around the 606 $aOligonucleotides$xAnalysis 606 $aBiochemistry 615 0$aOligonucleotides$xAnalysis. 615 0$aBiochemistry. 676 $a572.8/5 701 $aBonilla$b Jose V$01553678 701 $aSrivatsa$b Susan$01553679 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910781746803321 996 $aHandbook of analysis of oligonucleotides and related products$93814374 997 $aUNINA LEADER 04518nam 2200985 a 450 001 9910785340303321 005 20230725025638.0 010 $a1-282-91792-7 010 $a9786612917929 010 $a0-520-94802-5 024 7 $a10.1525/9780520948020 035 $a(CKB)2670000000059011 035 $a(EBL)613133 035 $a(OCoLC)697952920 035 $a(SSID)ssj0000437411 035 $a(PQKBManifestationID)11321662 035 $a(PQKBTitleCode)TC0000437411 035 $a(PQKBWorkID)10431775 035 $a(PQKB)10790673 035 $a(MiAaPQ)EBC613133 035 $a(DE-B1597)519606 035 $a(DE-B1597)9780520948020 035 $a(Au-PeEL)EBL613133 035 $a(CaPaEBR)ebr10432605 035 $a(CaONFJC)MIL291792 035 $a(EXLCZ)992670000000059011 100 $a20100222d2011 uy 0 101 0 $aeng 135 $aurcn||||||||| 181 $ctxt 182 $cc 183 $acr 200 14$aThe H.D. book$b[electronic resource] /$fRobert Duncan ; edited and with an introduction by Michael Boughn and Victor Coleman 210 $aBerkeley $cUniversity of California Press$d2011 215 $a1 online resource (693 p.) 225 0 $aThe collected writings of Robert Duncan ;$v1 300 $aA collection of 17 essays, composed from 1959 to 1964. 311 $a0-520-26075-9 320 $aIncludes bibliographical references and index. 327 $tFront matter --$tContents --$tIllustrations --$tAcknowledgments --$tIntroduction --$tBook 1. Beginnings --$tChapter 1 --$tChapter 2 --$tChapter 3 --$tChapter 4 --$tChapter 5 --$tChapter 6 --$tChapter 7 --$tChapter 8 --$tChapter 9 --$tChapter 10 --$tChapter 11 --$tAppendix 1. Preliminary Notes toward Book 3 of The H.D. Book --$tAppendix 2. Composition and Publication History of The H.D. Book --$tAppendix 3. A List of Works Cited by Robert Duncan in The H.D. Book --$tCredits --$tIndex 330 $aThis magisterial work, long awaited and long the subject of passionate speculation, is an unprecedented exploration of modern poetry and poetics by one of America's most acclaimed and influential postwar poets. What began in 1959 as a simple homage to the modernist poet H.D. developed into an expansive and unique quest to arrive at a poetics that would fuel Duncan's great work in the 1970's. A meditation on both the roots of modernism and its manifestation in the work of H.D., Ezra Pound, D.H. Lawrence, William Carlos Williams, Edith Sitwell, and many others, Duncan's wide-ranging book is especially notable for its illumination of the role women played in creation of literary modernism. Until now, The H.D. Book existed only in mostly out-of-print little magazines in which its chapters first appeared. Now, for the first time published in its entirety, as its author intended, this monumental work-at once an encyclopedia of modernism, a reinterpretation of its key players and texts, and a record of Duncan's quest toward a new poetics-is at last complete and available to a wide audience. 410 4$aThe Collected Writings of Robert Duncan 606 $aPoetry, Modern$y20th century$xHistory and criticism$xTheory, etc 610 $a20th century. 610 $aart and literature. 610 $acollected writings. 610 $adh lawrence. 610 $adiscussion books. 610 $aedith sitwell. 610 $aezra pound. 610 $afamous poets. 610 $ahd. 610 $alit scholars. 610 $alit studies. 610 $aliterary criticism. 610 $aliterary critics. 610 $aliterary figures. 610 $aliterary movements. 610 $aliterary theory. 610 $aliterary. 610 $amodern literature. 610 $amodern poetics. 610 $amodern poetry. 610 $amodernist poets. 610 $anonfiction. 610 $apostwar period. 610 $areference guide. 610 $aretrospective. 610 $arobert duncan. 610 $aroots of modernism. 610 $awilliam carlos williams. 610 $awriters. 615 0$aPoetry, Modern$xHistory and criticism$xTheory, etc. 676 $a814/.54 686 $a18.06$2bcl 700 $aDuncan$b Robert$f1919-1988.$0124018 701 $aBoughn$b Michael$01577322 701 $aColeman$b Victor$f1944-$01577323 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910785340303321 996 $aThe H.D. book$93855860 997 $aUNINA